DNA and RNA Extraction

CUSTOM DNA Extraction from mouse whole blood (white cell pellets) CUSTOM DNA and RNA Extraction from mouse organs (lung, spleen, heart, kidney, brain, liver) + Agilent RNA QC would introduce unavoidable differences in extraction chemistry, instrumentation, workflow, and QC thresholds, generating batch effects that would distort methylation signatures, gene expression profiles, and sequencing quality. These discrepancies cannot be corrected computationally and would render the new data scientifically incompatible with the previously generated dataset, undermining the validity of the combined analysis and jeopardizing both the submitted manuscript and the continuation study