# DNA and RNA Extraction

Canonical: https://abierto.us/opportunities/pcania02375

- Solicitation number: PCA-NIA-02375
- Notice type: Special notice
- Status: Closed. Deadline was March 30, 2026 at 6:00 AM EDT
- Department: Department of Health and Human Services
- Agency: National Institutes of Health
- Contracting office: National Institutes of Health Olao (75N980)
- NAICS: 541714 Research and Development in Biotechnology (except Nanobiotechnology)
- Product or service code: R499 Other Professional Services
- Place of performance: Bethesda, Maryland
- County: Montgomery County (FIPS 24031). https://abierto.us/counties/montgomery-county-md-24031
- City: Bethesda. https://abierto.us/cities/bethesda-md-2407125
- First posted: March 23, 2026
- Last posted: March 23, 2026
- SAM.gov: https://sam.gov/workspace/contract/opp/e718b7e348624613be7ec226f4bc09eb/view

## Description

CUSTOM DNA Extraction from mouse whole blood (white cell pellets) CUSTOM DNA and RNA Extraction from mouse organs (lung, spleen, heart, kidney, brain, liver) + Agilent RNA QC would introduce unavoidable differences in extraction chemistry, instrumentation, workflow, and QC thresholds, generating batch effects that would distort methylation signatures, gene expression profiles, and sequencing quality. These discrepancies cannot be corrected computationally and would render the new data scientifically incompatible with the previously generated dataset, undermining the validity of the combined analysis and jeopardizing both the submitted manuscript and the continuation study

## Publications

- March 23, 2026: Special notice. Notice 2869bf3e393744fbaacdf4e450e1c0a0. https://sam.gov/workspace/contract/opp/2869bf3e393744fbaacdf4e450e1c0a0/view
- March 23, 2026: Special notice, due March 30, 2026 at 6:00 AM EDT. Notice e718b7e348624613be7ec226f4bc09eb. https://sam.gov/workspace/contract/opp/e718b7e348624613be7ec226f4bc09eb/view

## Points of contact

- Cifford Lounsbury, clifford.lounsbury@nih.gov, 3014808827

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Source: SAM.gov Contract Opportunities bulk extract. Confirm deadlines on SAM.gov before responding. Cite https://abierto.us/opportunities/pcania02375.