Solicitation
ARPA-H Comprehensive Organ System Modeling in Outer Space (COSMOS) Innovative Solutions Opening
ARPA-H-SOL-26-165
National Institutes of Health, Advanced Research Projects Agency for Health (Arpa-H). Research and Development in Biotechnology (except Nanobiotechnology).
Offers due
October 7, 2026 at 2:00 PM EDT
20 days from now. Posted September 16, 2026.
Description
As published on SAM.gov.
The Advanced Research Projects Agency for Health (ARPA-H) Comprehensive Organ System Modeling in Outer Space (COSMOS) Initiative aims to definitively prove or disprove if exposure to microgravity in Low Earth Orbit (LEO) truly accelerates tissue aging across brain, cardiac, uterine, and kidney tissue types and across several adult age brackets. Provided Tissue Aging Rate in Space (TARIS) exceeds Tissue Aging Rate on Earth (TAROE) at a rate that exceeds the on Earth breakeven cost for new drug R&D, COSMOS will create a first-in-class platform for fully autonomous, high-throughput drug screening in LEO that would be more cost effective and faster than new drug R&D on Earth.
ARPA-H anticipates multiple Other Transaction awards resulting from this announcement.
Interested parties are invited to download and review the attached COSMOS Innovative Solutions Opening (ISO) ARPA-H-SOL-26-165
Attachments
Files listed on SAM.gov. The ones we hold a copy of download from here; the rest open SAM's download, which needs no account.
- ARPA-H-SOL-26-165_COSMOS_ISO.docx892 KB, September 16, 2026
Publications
Every notice SAM.gov issued under this solicitation number, oldest first. Each is a separate record on SAM.
September 16, 2026
Solicitation
Due October 7, 2026 at 2:00 PM EDT. SAM.gov, notice f7ed4368bf8c48e39ca45d3204830c25
1 revisions on SAM
- September 16, 2026: publish, solicitation
Points of contact
- COSMOS TeamCOSMOS@ARPA-H.GOV
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