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Solicitation

BIOmolecular Grammar for protein Aggregation Modulation and Intervention (BIOGAMI)

ARPA-H-SOL-26-149

National Institutes of Health, Advanced Research Projects Agency for Health (Arpa-H). Research and Development in Biotechnology (except Nanobiotechnology).

Response deadline

April 15, 2026 at 12:00 PM EDT

Closed 200 days ago. Posted March 24, 2026, first published January 30, 2026. Scheduled to archive April 30, 2026.

Get the next one like this from National Institutes of Health by email, the day it is posted.Find my opportunities

This one closed in 2026

18 like it are open now in research and development in biotechnology (except nanobiotechnology)

All 18 open in research and development in biotechnology (except nanobiotechnology)

Description

As published on SAM.gov.

24 March 2026 Update: This update replaces the original cost proposal spreadsheet (Appendix F) with one that incorporates the ISO's multi-party teaming terminology.

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All questions submitted to the ISO will be compiled and addressed. All answers will be posted to the BIOGAMI Frequently Asked Questions (FAQ) page. Potential proposers are encouraged to monitor the FAQs page regularly for the latest information and updates: https://arpa-h.gov/explore-funding/programs/biogami/faqs

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The Advanced Research Projects Agency for Health (ARPA-H) is posting this Innovative Solutions Opening (ISO) in support of the BIOmolecular Grammar for protein Aggregation Modulation and Intervention (BIOGAMI) Program. ARPA-H anticipates that multiple Other Transaction (OT) Agreements will result from this announcement.

Interested parties are invited to review the attached BIOGAMI_ISO_ARPA-H-SOL-26-149 and its Appendices A - J.

Additionally, proposers are encouraged to review the separate Special Notice, ARPA-H-SN-26-147, for information regarding the BIOGAMI Proposers’ Day. Special Notice, ARPA-H-SN-26-147, is an independent announcement and is not attached to this ISO announcement.

Attachments

Files listed on SAM.gov. The ones we hold a copy of download from here; the rest open SAM's download, which needs no account.

Publications

Every notice SAM.gov issued under this solicitation number, oldest first. Each is a separate record on SAM.

  1. January 30, 2026

    Solicitation

    Due April 15, 2026 at 12:00 PM EDT. SAM.gov, notice 23802b14ac3d4c79bd67c6cac7e06db5

    3 revisions on SAM
    • March 24, 2026: publish, solicitation
    • February 18, 2026: publish, solicitation
    • January 30, 2026: publish, solicitation
  2. February 18, 2026

    Solicitation

    Due April 15, 2026 at 12:00 PM EDT. SAM.gov, notice 5af8f100073345458dbdb604e4f9632c

    3 revisions on SAM
    • March 24, 2026: publish, solicitation
    • February 18, 2026: publish, solicitation
    • January 30, 2026: publish, solicitation
  3. March 24, 2026

    Solicitation

    Due April 15, 2026 at 12:00 PM EDT. SAM.gov, notice 8b366d45d6214eb891f7a4f018791f39

    3 revisions on SAM
    • March 24, 2026: publish, solicitation
    • February 18, 2026: publish, solicitation
    • January 30, 2026: publish, solicitation

Points of contact