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Special notice, total small business set-aside, first published as sources sought

The Therapeutic Role of Soluble Adenylyl Cyclase Inhibition in Ameliorating Inflammatory Vascular Remodeling in Pulmonary Arterial Hypertension

75N98026R00085

National Institutes of Health, National Institute of Health NIH-OD. Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology).

127 open like this View on SAM.gov Markdown

Awarded

Arbor Research, LLC

$770,906.97 obligated so far on USAspending

Get the next one like this from National Institutes of Health by email, the day it is posted.Find my opportunities

This one was awarded in 2026

127 like it are open now in research and development in the physical, engineering, and life sciences (except nanotechnology and biotechnology)

All 127 open in research and development in the physical, engineering, and life sciences (except nanotechnology and biotechnology)

Description

As published on SAM.gov.

The National Institutes of Health (NIH) intends to negotiate on a sole-source basis with the University of Illinois at Chicago (UIC) for preclinical animal research services to evaluate the therapeutic effects of soluble adenylyl cyclase (sAC) inhibition on pulmonary arterial hypertension (PAH) using an established endothelial cell-specific Cav1 knockout (EC-Cav1 KO) murine model and corresponding wild-type controls.

The Government intends to solicit from a single source pursuant to FAR 13.106-1(b)(1). UIC currently maintains the established EC-Cav1 KO mouse colony required for this study, and the model is not known to be maintained by another laboratory.

This notice of intent is not a request for competitive quotations. However, all responsible sources that believe they can satisfy the Government's requirements may submit a capability statement and/or quotation for consideration by the Government.

Please see the attached Notice of Intent to Sole Source for the complete description of the requirement, basis for the intended sole-source acquisition, response instructions, and applicable response deadline.

Attachments

Files listed on SAM.gov. The ones we hold a copy of download from here; the rest open SAM's download, which needs no account.

The contract, on USAspending

Federal procurement data the awarding office reported to FPDS, matched to this solicitation by its number.

Recipient
Arbor Research, LLC
UEI
DVSNRG76MU54
CAGE
99AG7
Vendor location
Ann Arbor, MI
Contract
75N98026F00459 under 47QRAA24D00BA, delivery order
Obligated
$770,906.97, potential $2,997,347
Actions
1 between September 29, 2026 and September 29, 2026
Competition
Full and Open Competition, 7 offers received
Described as
Nhlbi Innovation and Commercialization Ecosystem: Product Development Support and Program Evaluation
Match
solicitation number 75N98026R00085 equals the FPDS solicitation identifier; same sub-agency 7529 (high confidence)
Record
USAspending award page

Publications

Every notice SAM.gov issued under this solicitation number, oldest first. Each is a separate record on SAM.

  1. June 4, 2026

    Sources sought

    NHLBI Innovation and Commercialization Ecosystem: Product Development Support and Program Evaluation

    Due June 18, 2026 at 4:00 PM EDT. SAM.gov, notice adfd909f33094919925b63daff11cf84

    1 revisions on SAM
    • June 4, 2026: publish, sources sought

  2. September 14, 2026

    Special notice

    Due September 21, 2026 at 12:00 PM EDT. SAM.gov, notice 955c40f8d97c42e081a4c82c09bdb80c

    1 revisions on SAM
    • September 14, 2026: publish, special notice

Points of contact