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Combined synopsis and solicitation

Illumina DRAGEN Tier 3 Throughput License and v4 Server

75N98026Q01167

National Institutes of Health, National Institutes of Health NLM. Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology).

127 open like this View on SAM.gov Markdown

Response deadline

September 14, 2026 at 9:00 AM EDT

Closed 48 days ago. Posted September 10, 2026, first published September 9, 2026. Scheduled to archive September 29, 2026.

Get the next one like this from National Institutes of Health by email, the day it is posted.Find my opportunities

This one closed 48 days ago

127 like it are open now in research and development in the physical, engineering, and life sciences (except nanotechnology and biotechnology)

All 127 open in research and development in the physical, engineering, and life sciences (except nanotechnology and biotechnology)

Description

As published on SAM.gov.

The NHGRI Undiagnosed Diseases Program (UDP) requires both the Illumina DRAGEN 500,000Gb annual throughput license and the Illumina DRAGEN Server v4 to maintain secure, compliant, and high performance secondary analysis of next generation sequencing (NGS) data. DRAGEN serves as an essential computational supplement when UDP’s sequencing workload exceeds CIT High Performance Computing Center allocations, enabling timely processing of whole genome, whole exome, and transcriptome datasets for patients with rare and unresolved diseases.  The current DRAGEN server, procured in 2017, has reached end of support. Its CentOS 7 operating system lost vendor support and security updates on June 30, 2024, increasing operational risk. In addition, the legacy dual Intel Xeon processors, 512 Gb RAM, and first generation FPGA acceleration hardware cannot support updated DRAGEN pipelines, including pangenome references and improved germline/somatic variant calling workflows. These limitations reduce analytical accuracy, throughput, and system stability.  To prevent analysis delays, maintain compliance with NIH IT security requirements, and sustain mission critical genomic interpretation capacity, the UDP must acquire both the updated throughput license and the next generation DRAGEN Server v4.

Attachments

Files listed on SAM.gov. The ones we hold a copy of download from here; the rest open SAM's download, which needs no account.

Publications

Every notice SAM.gov issued under this solicitation number, oldest first. Each is a separate record on SAM.

  1. September 9, 2026

    Combined synopsis and solicitation

    Due September 11, 2026 at 3:00 PM EDT. SAM.gov, notice 2b9f1975c69948c99638f657791eb996

    4 revisions on SAM
    • September 10, 2026: publish, combined synopsis and solicitation
    • September 9, 2026: publish, combined synopsis and solicitation
    • September 9, 2026: publish, combined synopsis and solicitation
    • August 19, 2026: publish, sources sought

  2. September 9, 2026

    Combined synopsis and solicitation, originally sources sought

    Due September 11, 2026 at 3:00 PM EDT. SAM.gov, notice 6b98c12f393e4bff977b9287862a1355

    4 revisions on SAM
    • September 10, 2026: publish, combined synopsis and solicitation
    • September 9, 2026: publish, combined synopsis and solicitation
    • September 9, 2026: publish, combined synopsis and solicitation
    • August 19, 2026: publish, sources sought

  3. September 10, 2026

    Combined synopsis and solicitation

    Due September 14, 2026 at 9:00 AM EDT. SAM.gov, notice 6aea684c50ec4b30a97ec93f50bb2d70

    4 revisions on SAM
    • September 10, 2026: publish, combined synopsis and solicitation
    • September 9, 2026: publish, combined synopsis and solicitation
    • September 9, 2026: publish, combined synopsis and solicitation
    • August 19, 2026: publish, sources sought

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