# Illumina DRAGEN Tier 3 Throughput License and v4 Server

Canonical: https://abierto.us/opportunities/75n98026q01167

- Solicitation number: 75N98026Q01167
- Notice type: Combined synopsis and solicitation
- Status: Closed. Deadline was September 14, 2026 at 9:00 AM EDT
- Department: Department of Health and Human Services
- Agency: National Institutes of Health
- Contracting office: National Institutes of Health NLM (75N970)
- NAICS: 541715 Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
- Product or service code: AJ12 General Science And Technology R&D Services; General Science And Technology; Applied Research
- Place of performance: Bethesda, Maryland
- County: Montgomery County (FIPS 24031). https://abierto.us/counties/montgomery-county-md-24031
- City: Bethesda. https://abierto.us/cities/bethesda-md-2407125
- First posted: September 9, 2026
- Last posted: September 10, 2026
- SAM.gov: https://sam.gov/workspace/contract/opp/6aea684c50ec4b30a97ec93f50bb2d70/view

## Description

The NHGRI Undiagnosed Diseases Program (UDP) requires both the Illumina DRAGEN 500,000Gb annual throughput license and the Illumina DRAGEN Server v4 to maintain secure, compliant, and high performance secondary analysis of next generation sequencing (NGS) data. DRAGEN serves as an essential computational supplement when UDP’s sequencing workload exceeds CIT High Performance Computing Center allocations, enabling timely processing of whole genome, whole exome, and transcriptome datasets for patients with rare and unresolved diseases.  The current DRAGEN server, procured in 2017, has reached end of support. Its CentOS 7 operating system lost vendor support and security updates on June 30, 2024, increasing operational risk. In addition, the legacy dual Intel Xeon processors, 512 Gb RAM, and first generation FPGA acceleration hardware cannot support updated DRAGEN pipelines, including pangenome references and improved germline/somatic variant calling workflows. These limitations reduce analytical accuracy, throughput, and system stability.  To prevent analysis delays, maintain compliance with NIH IT security requirements, and sustain mission critical genomic interpretation capacity, the UDP must acquire both the updated throughput license and the next generation DRAGEN Server v4.

## Attachments

- [DRAGEN_Combined_SOW.pdf](https://sam.gov/api/prod/opps/v3/opportunities/resources/files/502544a496be4ada9714a9a4cf91c63a/download)

## Publications

- September 9, 2026: Combined synopsis and solicitation, due September 11, 2026 at 3:00 PM EDT. Notice 2b9f1975c69948c99638f657791eb996. https://sam.gov/workspace/contract/opp/2b9f1975c69948c99638f657791eb996/view
- September 9, 2026: Combined synopsis and solicitation, due September 11, 2026 at 3:00 PM EDT. Notice 6b98c12f393e4bff977b9287862a1355. https://sam.gov/workspace/contract/opp/6b98c12f393e4bff977b9287862a1355/view
- September 10, 2026: Combined synopsis and solicitation, due September 14, 2026 at 9:00 AM EDT. Notice 6aea684c50ec4b30a97ec93f50bb2d70. https://sam.gov/workspace/contract/opp/6aea684c50ec4b30a97ec93f50bb2d70/view

## Points of contact

- Sandra Daniels, Sandra.Daniels@nih.gov
- Shirley Ruiz-Lundgren, Shirley.ruiz-lundgren@nih.gov, 3018277529

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Source: SAM.gov Contract Opportunities bulk extract. Confirm deadlines on SAM.gov before responding. Cite https://abierto.us/opportunities/75n98026q01167.