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Award notice, total small business set-aside, first published as presolicitation

Evaluation and Conduct of Computational and Alternative Toxicological Methods for the National Institute of Environmental Health Sciences

75N96025R00004

National Institutes of Health, National Institute of Health Niehs. Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology).

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Awarded

Sciome LLC

$79,295,984.98 on the award notice, August 25, 2026, contract 75N94026C00002

Description

As published on SAM.gov.

This R&D contract will facilitate the National Institute of Environmental Health Sciences (NIEHS) by conducting and evaluating toxicological testing using computational and/or alternative approaches, also referred to as New Approach Methodologies (NAMs). NAMs broadly refers to any technology, methodology, approach, and/or combination of the three than can provide information on chemical hazard and risk assessment without the use of animals, such as silico, in chemico, in vitro, and ex vivo approaches. The areas of focus for research include, but are not limited to, population variability, susceptibility, developmental neurotoxicity, carcinogenicity, ecotoxicity and acute toxicity.

The contract, on USAspending

Federal procurement data the awarding office reported to FPDS, matched to this solicitation by its number.

Recipient
Sciome LLC
UEI
TALRGESRV6C8
CAGE
651N8
Vendor location
Durham, NC
Contract
75N94026C00002, definitive contract
Obligated
$5,463,756.54, potential $79,295,985
Actions
2 between August 25, 2026 and September 11, 2026
Competition
Full and Open Competition After Exclusion of Sources, 6 offers received
Set-aside reported
Small Business Set Aside - Total
Described as
EO14398 Evaluation and Conduct of Computational and Alternative Toxicological Research for the National Institute of Environmental Health Sciences. Contractor Conducts and Evaluates Toxicological Testing Using Computational And/Or Alternative Approa
Match
award number 75N94026C00002 equals the contract number; same sub-agency 7529 (high confidence)
Record
USAspending award page

Publications

Every notice SAM.gov issued under this solicitation number, oldest first. Each is a separate record on SAM.

  1. November 8, 2024

    Presolicitation, originally sources sought

    Support for Evaluating and Conducting Computational and Alternative Toxicological Methods for the National Institute of Environmental Health Sciences

    Due November 24, 2024 at 5:00 PM EST. SAM.gov, notice bd543fdd316b4bad803ea2c70a0172e1

  2. May 14, 2025

    Presolicitation

    Support for Evaluating and Conducting Computational and Alternative Toxicological Methods for the National Institute of Environmental Health Sciences

    Due June 2, 2025 at 5:00 PM EDT. SAM.gov, notice b1aede92352c484990b2032c6801d113

  3. May 14, 2025

    Presolicitation

    Support for Evaluating and Conducting Computational and Alternative Toxicological Methods for the National Institute of Environmental Health Sciences

    Due June 2, 2025 at 5:00 PM EDT. SAM.gov, notice b67309904bc5457e829651b8b96b1674

  4. September 17, 2025

    Solicitation, originally presolicitation

    Support for Evaluating and Conducting Computational and Alternative Toxicological Methods for the National Institute of Environmental Health Sciences

    Due November 3, 2025 at 4:30 PM EST. SAM.gov, notice f267edcc4cca49f6a9d82f49917b4009

  5. November 3, 2025

    Solicitation

    Support for Evaluating and Conducting Computational and Alternative Toxicological Methods for the National Institute of Environmental Health Sciences

    Due December 5, 2025 at 4:30 PM EST. SAM.gov, notice 0fcec10cc2bc488bbd226b914e4fe244

  6. November 25, 2025

    Solicitation

    Support for Evaluating and Conducting Computational and Alternative Toxicological Methods for the National Institute of Environmental Health Sciences

    Due December 19, 2025 at 4:30 PM EST. SAM.gov, notice be133512f3414d77b20c63a69e819345

  7. August 27, 2026

    Award notice, originally solicitation

    Awarded to SCIOME LLC Durham for $79,295,985. SAM.gov, notice 4d90db3cbfbb4891888e60120c2a3747

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