Award notice, total small business set-aside, first published as presolicitation
Evaluation and Conduct of Computational and Alternative Toxicological Methods for the National Institute of Environmental Health Sciences
75N96025R00004
National Institutes of Health, National Institute of Health Niehs. Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology).
Awarded
$79,295,984.98 on the award notice, August 25, 2026, contract 75N94026C00002
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This one was awarded in 2025
127 like it are open now in research and development in the physical, engineering, and life sciences (except nanotechnology and biotechnology)
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Description
As published on SAM.gov.
This R&D contract will facilitate the National Institute of Environmental Health Sciences (NIEHS) by conducting and evaluating toxicological testing using computational and/or alternative approaches, also referred to as New Approach Methodologies (NAMs). NAMs broadly refers to any technology, methodology, approach, and/or combination of the three than can provide information on chemical hazard and risk assessment without the use of animals, such as silico, in chemico, in vitro, and ex vivo approaches. The areas of focus for research include, but are not limited to, population variability, susceptibility, developmental neurotoxicity, carcinogenicity, ecotoxicity and acute toxicity.
Attachments
Files listed on SAM.gov. The ones we hold a copy of download from here; the rest open SAM's download, which needs no account.
- RFP 75N96025R00004.pdf2.0 MB, September 17, 2025
The contract, on USAspending
Federal procurement data the awarding office reported to FPDS, matched to this solicitation by its number.
- Recipient
- Sciome LLC
- UEI
- TALRGESRV6C8
- CAGE
- 651N8
- Vendor location
- Durham, NC
- Contract
- 75N94026C00002, definitive contract
- Obligated
- $5,463,756.54, potential $79,295,985
- Actions
- 2 between August 25, 2026 and September 11, 2026
- Competition
- Full and Open Competition After Exclusion of Sources, 6 offers received
- Set-aside reported
- Small Business Set Aside - Total
- Described as
- EO14398 Evaluation and Conduct of Computational and Alternative Toxicological Research for the National Institute of Environmental Health Sciences. Contractor Conducts and Evaluates Toxicological Testing Using Computational And/Or Alternative Approa
- Match
- award number 75N94026C00002 equals the contract number; same sub-agency 7529 (high confidence)
- Record
- USAspending award page
Publications
Every notice SAM.gov issued under this solicitation number, oldest first. Each is a separate record on SAM.
November 8, 2024
Presolicitation, originally sources sought
Support for Evaluating and Conducting Computational and Alternative Toxicological Methods for the National Institute of Environmental Health Sciences
Due November 24, 2024 at 5:00 PM EST. SAM.gov, notice bd543fdd316b4bad803ea2c70a0172e1
May 14, 2025
Presolicitation
Support for Evaluating and Conducting Computational and Alternative Toxicological Methods for the National Institute of Environmental Health Sciences
Due June 2, 2025 at 5:00 PM EDT. SAM.gov, notice b1aede92352c484990b2032c6801d113
May 14, 2025
Presolicitation
Support for Evaluating and Conducting Computational and Alternative Toxicological Methods for the National Institute of Environmental Health Sciences
Due June 2, 2025 at 5:00 PM EDT. SAM.gov, notice b67309904bc5457e829651b8b96b1674
September 17, 2025
Solicitation, originally presolicitation
Support for Evaluating and Conducting Computational and Alternative Toxicological Methods for the National Institute of Environmental Health Sciences
Due November 3, 2025 at 4:30 PM EST. SAM.gov, notice f267edcc4cca49f6a9d82f49917b4009
4 revisions on SAM
- November 25, 2025: publish, solicitation
- November 3, 2025: publish, solicitation
- September 2, 2025: publish, presolicitation
- September 17, 2025: publish, solicitation
November 3, 2025
Solicitation
Support for Evaluating and Conducting Computational and Alternative Toxicological Methods for the National Institute of Environmental Health Sciences
Due December 5, 2025 at 4:30 PM EST. SAM.gov, notice 0fcec10cc2bc488bbd226b914e4fe244
4 revisions on SAM
- November 25, 2025: publish, solicitation
- November 3, 2025: publish, solicitation
- September 2, 2025: publish, presolicitation
- September 17, 2025: publish, solicitation
November 25, 2025
Solicitation
Support for Evaluating and Conducting Computational and Alternative Toxicological Methods for the National Institute of Environmental Health Sciences
Due December 19, 2025 at 4:30 PM EST. SAM.gov, notice be133512f3414d77b20c63a69e819345
5 revisions on SAM
- August 27, 2026: publish, award notice
- November 25, 2025: publish, solicitation
- November 3, 2025: publish, solicitation
- September 2, 2025: publish, presolicitation
- September 17, 2025: publish, solicitation
August 27, 2026
Award notice, originally solicitation
Awarded to Sciome LLC for $79,295,985. SAM.gov, notice 4d90db3cbfbb4891888e60120c2a3747
2 revisions on SAM
- August 27, 2026: publish, award notice
- November 25, 2025: publish, solicitation
Points of contact
- Jason Williamsjason.williams2@nih.gov301-443-3877
- Lisa Schaupplisa.schaupp@nih.gov301-827-8135