# Evaluation and Conduct of Computational and Alternative Toxicological Methods for the National Institute of Environmental Health Sciences

Canonical: https://abierto.us/opportunities/75n96025r00004

- Solicitation number: 75N96025R00004
- Notice type: Award notice (first published as presolicitation)
- Status: Awarded to Sciome LLC for $79,295,984.98
- Department: Department of Health and Human Services
- Agency: National Institutes of Health
- Contracting office: National Institute of Health Niehs (75N960)
- NAICS: 541715 Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
- Product or service code: AJ11 General Science And Technology R&D Services; General Science And Technology; Basic Research
- Set-aside: Total small business set-aside
- County: Durham County (FIPS 37063). https://abierto.us/counties/durham-county-nc-37063
- City: Durham. https://abierto.us/cities/durham-nc-3719000
- First posted: November 8, 2024
- Last posted: August 27, 2026
- SAM.gov: https://sam.gov/workspace/contract/opp/4d90db3cbfbb4891888e60120c2a3747/view

## Description

This R&D contract will facilitate the National Institute of Environmental Health Sciences (NIEHS) by conducting and evaluating toxicological testing using computational and/or alternative approaches, also referred to as New Approach Methodologies (NAMs). NAMs broadly refers to any technology, methodology, approach, and/or combination of the three than can provide information on chemical hazard and risk assessment without the use of animals, such as silico, in chemico, in vitro, and ex vivo approaches. The areas of focus for research include, but are not limited to, population variability, susceptibility, developmental neurotoxicity, carcinogenicity, ecotoxicity and acute toxicity.

## Award on USAspending

- Recipient: Sciome LLC (UEI TALRGESRV6C8)
- Contract: 75N94026C00002, definitive contract
- Obligated: $5,463,756.54
- Competition: Full and Open Competition After Exclusion of Sources, 6 offers received
- Link: award number 75N94026C00002 equals the contract number; same sub-agency 7529 (high confidence)
- Record: https://www.usaspending.gov/award/CONT_AWD_75N94026C00002_7529_-NONE-_-NONE-/


## Publications

- November 8, 2024: Presolicitation, due November 24, 2024 at 5:00 PM EST. Notice bd543fdd316b4bad803ea2c70a0172e1. https://sam.gov/workspace/contract/opp/bd543fdd316b4bad803ea2c70a0172e1/view
- May 14, 2025: Presolicitation, due June 2, 2025 at 5:00 PM EDT. Notice b1aede92352c484990b2032c6801d113. https://sam.gov/workspace/contract/opp/b1aede92352c484990b2032c6801d113/view
- May 14, 2025: Presolicitation, due June 2, 2025 at 5:00 PM EDT. Notice b67309904bc5457e829651b8b96b1674. https://sam.gov/workspace/contract/opp/b67309904bc5457e829651b8b96b1674/view
- September 17, 2025: Solicitation, due November 3, 2025 at 4:30 PM EST. Notice f267edcc4cca49f6a9d82f49917b4009. https://sam.gov/workspace/contract/opp/f267edcc4cca49f6a9d82f49917b4009/view
- November 3, 2025: Solicitation, due December 5, 2025 at 4:30 PM EST. Notice 0fcec10cc2bc488bbd226b914e4fe244. https://sam.gov/workspace/contract/opp/0fcec10cc2bc488bbd226b914e4fe244/view
- November 25, 2025: Solicitation, due December 19, 2025 at 4:30 PM EST. Notice be133512f3414d77b20c63a69e819345. https://sam.gov/workspace/contract/opp/be133512f3414d77b20c63a69e819345/view
- August 27, 2026: Award notice. Notice 4d90db3cbfbb4891888e60120c2a3747. https://sam.gov/workspace/contract/opp/4d90db3cbfbb4891888e60120c2a3747/view

## Points of contact

- Jason Williams, jason.williams2@nih.gov, 301-443-3877
- Lisa Schaupp, lisa.schaupp@nih.gov, 301-827-8135

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Source: SAM.gov Contract Opportunities bulk extract and USAspending.gov award data. Confirm deadlines on SAM.gov before responding. Cite https://abierto.us/opportunities/75n96025r00004.