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Combined synopsis and solicitation

DNA Methylation & Genome Wide Association assays for evaluating changes in Epigenetic Aging for Veterans with HIV who participated in a Telehealth-delivered High-Intensity Exercise Program

36C24E24Q0139

Department of Veterans Affairs, Rpo East. Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology).

Awarded

Tempus Ai, Inc.

$66,869.00 obligated so far on USAspending

Description

As published on SAM.gov.

Amendment 1 Answer Vendor Questions for Solicitation 36C24E24Q0139.

Question 1: We are performing independent research on the Combined Synopsis/Solicitation (36C24E24Q0139). We would like to know if this is a brand new contract OR if there is (was) an incumbent performing these services. If not brand new, could you please provide the current / previous contract number? Appreciate any insight you can provide.

Answer to Question 1: This is new and there is no incumbent performing these services for the Requesting Activity for VA Portland Health Care System. Questions 2-8 were sent in together* Question 2: We utilize a custom EPIC V2 array with additional information. Would that array be appropriate to use for this project or would the standard EPIC V2 array be more appropriate?

Answer to Question 2: The standard version of EPIC V2 array is what is planned for use.

Question 3: Are the 102 samples to be used for GWAS a subset of the 191 or a separate cohort? In either case, can you help me better understand the expectation for sample processing in Item Number 4?

Answer to Question 3: The 102 is a subset of the 191. The sample processing is any required processing to do the required assays only.

Question 4: Is there an expectation to use genotyping arrays for the GWAS? If so, is there a preference or would one of the arrays we use for MVP be appropriate?

Answer to Question 4: The GWAS array genotyping is part of the study. The MVP array is fine, as well as the Illumina GSA array.

Question 5: Would PacBio long read sequencing be considered for the GWAS?

Answer to Question 5: No, only the GWAS array for genotyping. See (3) above.

Question 6: What should be the disposition of the samples once the assays are finished?

Answer to Question 6: If possible, would be best to return to us.

Question 7: Is there an expectation for data analysis beyond providing the raw data?

Answer to Question 7: No data analysis needed.

Question 8: What are the requirements for data delivery?

Answer Question 8: Encrypted and sent via secure FTP. Upon award this will be facilitated.

The contract, on USAspending

Federal procurement data the awarding office reported to FPDS, matched to this solicitation by its number.

UEI
PW4TQZ3KDLU3
CAGE
7WPH7
Vendor location
Chicago, IL
Contract
36C24E24P0114, purchase order
Obligated
$66,869.00
Actions
2 between September 30, 2024 and February 10, 2026
Competition
Competed Under SAP, 5 offers received
Set-aside reported
No Set Aside Used.
Described as
Dna Methylation Services for Teleconferencing Exercise Study in Hiv + Patients
Match
solicitation number 36C24E24Q0139 equals the FPDS solicitation identifier; same awarding office 36C24E (high confidence)

Publications

Every notice SAM.gov issued under this solicitation number, oldest first. Each is a separate record on SAM.

  1. September 24, 2024

    Combined synopsis and solicitation

    DNA Methylation & Genome Wide Association assays for evaluating changes in Epigenetic Aging for Veterans with HIV who participated in a Telehealth-delivered High-Intensity Exercise Programs

    Due September 27, 2024 at 9:00 AM EDT. SAM.gov, notice 2b48a0f630c04f00a74853156812939a

  2. September 26, 2024

    Combined synopsis and solicitation

    Due September 27, 2024 at 9:00 AM EDT. SAM.gov, notice 647c45933e9e403b989b3f9042c2952a

Points of contact