# DNA Methylation & Genome Wide Association assays for evaluating changes in Epigenetic Aging for Veterans with HIV who participated in a Telehealth-delivered High-Intensity Exercise Program

Canonical: https://abierto.us/opportunities/36c24e24q0139

- Solicitation number: 36C24E24Q0139
- Notice type: Combined synopsis and solicitation
- Status: Awarded to Tempus Ai, Inc.
- Department: Department of Veterans Affairs
- Contracting office: Rpo East (36C24E)
- NAICS: 541715 Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
- Product or service code: AN12 Health R&D Services; Health Care Services; Applied Research
- County: Cook County (FIPS 17031). https://abierto.us/counties/cook-county-il-17031
- City: Chicago. https://abierto.us/cities/chicago-il-1714000
- First posted: September 24, 2024
- Last posted: September 26, 2024
- SAM.gov: https://sam.gov/workspace/contract/opp/647c45933e9e403b989b3f9042c2952a/view

## Description

Amendment 1 Answer Vendor Questions for Solicitation 36C24E24Q0139.

**Question 1:** We are performing independent research on the Combined Synopsis/Solicitation (36C24E24Q0139). We would like to know if this is a brand new contract OR if there is (was) an incumbent performing these services. If not brand new, could you please provide the current / previous contract number? Appreciate any insight you can provide.

**Answer to Question 1:** This is new and there is no incumbent performing these services for the Requesting Activity for VA Portland Health Care System. Questions 2-8 were sent in together* Question 2: We utilize a custom EPIC V2 array with additional information. Would that array be appropriate to use for this project or would the standard EPIC V2 array be more appropriate?

**Answer to Question 2:** The standard version of EPIC V2 array is what is planned for use.

**Question 3:** Are the 102 samples to be used for GWAS a subset of the 191 or a separate cohort? In either case, can you help me better understand the expectation for sample processing in Item Number 4?

**Answer to Question 3:** The 102 is a subset of the 191. The sample processing is any required processing to do the required assays only.

**Question 4:** Is there an expectation to use genotyping arrays for the GWAS? If so, is there a preference or would one of the arrays we use for MVP be appropriate?

**Answer to Question 4:** The GWAS array genotyping is part of the study. The MVP array is fine, as well as the Illumina GSA array.

**Question 5:** Would PacBio long read sequencing be considered for the GWAS?

**Answer to Question 5:** No, only the GWAS array for genotyping. See (3) above.

**Question 6:** What should be the disposition of the samples once the assays are finished?

**Answer to Question 6:** If possible, would be best to return to us.

**Question 7:** Is there an expectation for data analysis beyond providing the raw data?

**Answer to Question 7:** No data analysis needed.

**Question 8:** What are the requirements for data delivery?

**Answer Question 8:** Encrypted and sent via secure FTP. Upon award this will be facilitated.

## Award on USAspending

- Recipient: Tempus Ai, Inc. (UEI PW4TQZ3KDLU3)
- Contract: 36C24E24P0114, purchase order
- Obligated: $66,869.00
- Competition: Competed Under SAP, 5 offers received
- Link: solicitation number 36C24E24Q0139 equals the FPDS solicitation identifier; same awarding office 36C24E (high confidence)
- Record: https://www.usaspending.gov/award/CONT_AWD_36C24E24P0114_3600_-NONE-_-NONE-/


## Publications

- September 24, 2024: Combined synopsis and solicitation, due September 27, 2024 at 9:00 AM EDT. Notice 2b48a0f630c04f00a74853156812939a. https://sam.gov/workspace/contract/opp/2b48a0f630c04f00a74853156812939a/view
- September 26, 2024: Combined synopsis and solicitation, due September 27, 2024 at 9:00 AM EDT. Notice 647c45933e9e403b989b3f9042c2952a. https://sam.gov/workspace/contract/opp/647c45933e9e403b989b3f9042c2952a/view

## Points of contact

- Karly Gabrysiak, Contract Specialist, Karly.gabrysiak@va.gov, E-Mail only

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Source: SAM.gov Contract Opportunities bulk extract and USAspending.gov award data. Confirm deadlines on SAM.gov before responding. Cite https://abierto.us/opportunities/36c24e24q0139.