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Solicitation

FY2022-2026 DTRA Chemical / Biological Technologies Broad Agency Announcement

HDTRA122S0002

Defense Threat Reduction Agency, Defense Threat Reduction Agency. Scientific Research and Development Services.

Awarded

Signature Science LLC

$2,609,140.92 obligated so far on USAspending

Get the next one like this from Defense Threat Reduction Agency by email, the day it is posted.Find my opportunities

This one was awarded in 2022

4 like it are open now in scientific research and development services

All 4 open in scientific research and development services

Description

As published on SAM.gov.

UPDATED AUGUST 25, 2026: TOPIC CALL 7, QUESTIONS & ANSWERS (Q and A_Ph I) 

UPDATED JULY 8, 2026: TOPIC CALL 7

THE DEADLINE TO SUBMIT QUESTIONS RELATED TO THE TOPICS INCLUDED IN TOPIC CALL 7 IS JULY 22, 2026.

THE DEADLINE TO SUBMIT A PROPOSAL FOR THE TOPICS INCLUDED IN TOPIC CALL 7 IS SEPTEMBER 2, 2026 AT 2:00PM EDT.

UPDATED AUGUST 20, 2025: SECTIONS 4.8.2.3.1, 4.8.2.3.8, AND 9.0 OF THE BAA HAVE BEEN REVISED AND SECTION 4.8.2.3.17 HAS BEEN ADDED. ATTACHMENTS 6 AND 7 HAVE BEEN REVISED. 

UPDATED MARCH 11, 2025: TOPIC CALL 6, QUESTIONS & ANSWERS (Q and A_Ph I) 

UPDATED FEBRUARY 13, 2025: TOPIC CALL 6

THE DEADLINE TO SUBMIT QUESTIONS RELATED TO THE TOPICS INCLUDED IN TOPIC CALL 6 IS FEBRUARY 27, 2025.

THE DEADLINE TO SUBMIT A PROPOSAL FOR THE TOPICS INCLUDED IN TOPIC CALL 6 IS APRIL 10, 2025 AT 2:00PM EDT.

UPDATED AUGUST 30, 2024: TOPIC CALL 5, QUESTIONS & ANSWERS (Q and A_Ph II)

UPDATED AUGUST 30, 2024: TOPIC CALL 4, QUESTIONS & ANSWERS (Q and A_Ph II)

UPDATED JUNE 6, 2024: TOPIC CALL 5, QUESTIONS & ANSWERS (Q and A_PhI)

UPDATED MAY 10, 2024: TOPIC CALL 4, QUESTIONS & ANSWERS (Q and A_Ph I) 

UPDATED APRIL 30, 2024:  TOPIC CALL 5

THE DEADLINE TO SUBMIT QUESTIONS RELATED TO THE TOPIC INCLUDED IN TOPIC CALL 5 IS MAY 14, 2024.

THE DEADLINE TO SUBMIT A PROPOSAL FOR THE TOPIC INCLUDED IN TOPIC CALL 5 IS JUNE 25, 2024 AT 2:00PM EDT.

UPDATED APRIL 1, 2024:  TOPIC CALL 4

THE DEADLINE TO SUBMIT QUESTIONS RELATED TO TOPICS INCLUDED IN TOPIC CALL 4 IS APRIL 16, 2024.

THE DEADLINE TO SUBMIT A PROPOSAL FOR TOPICS INCLUDED IN TOPIC CALL 4 IS MAY 29, 2024 AT 2:00PM EDT.

UPDATED SEPTEMBER 29, 2023:  TOPIC CALL 3, QUESTIONS & ANSWERS (Q and A)

UPDATED SEPTEMBER 6, 2023: TOPIC CALL 3

THE DEADLINE TO SUBMIT QUESTIONS RELATED TO TOPICS INCLUDED IN TOPIC CALL 3 IS SEPTEMBER 18, 2023.

THE DEADLINE TO SUBMIT A PROPOSAL FOR TOPICS INCLUDED IN TOPIC CALL 3 IS OCTOBER 26, 2023 AT 2:00PM EDT. 

UPDATED AUGUST 14, 2023:  TOPIC CALL 2, QUESTIONS & ANSWERS (Q and A_Ph II)

UPDATED APRIL 24, 2023:  TOPIC CALL 2, QUESTIONS & ANSWERS (Q and A_Ph I) 

UPDATED MARCH 21, 2023:  TOPIC CALL 2

THE DEADLINE TO SUBMIT QUESTIONS RELATED TO TOPICS INCLUDED IN TOPIC CALL 2 IS MARCH 28, 2023.

THE DEADLINE TO SUBMIT A PHASE I PROPOSAL FOR TOPICS INCLUDED IN TOPIC CALL 2 IS MAY 10, 2023 AT 2:00PM EDT. 

UPDATED NOV 10, 2022: TOPIC CALL 1, QUESTIONS & ANSWERS (Q and A_Ph II)

The purpose of this BAA is to serve as a five-year (60-month) open continuous vehicle through which topics will be released as individual calls as they become available during the BAA open period. This BAA will remain open for five years from the date of release.

The scope of this BAA is limited to projects that meet Technology Readiness Level (TRL) definitions in the TRL range of 3-6 (see ATTACHMENT 1 for TRL definitions). Upon completion of the proposed development efforts, solutions should strive to meet a TRL in the range of 4-6. Proposals that address technologies at TRL 4 or greater should also be aware of the Manufacturing Readiness Level (MRL) considerations.

The DTRA RD-CB mission was established by the Department of Defense (DoD) to provide state-of-the-art defense capabilities to allow military forces of the United States to operate and to successfully complete their missions in chemical and biological warfare environments. The scope of mission efforts and the priorities assigned to specific projects are influenced by changes in military and civilian Chemical and Biological Defense (CBD) science and technology, advanced developments, operational requirements, military threat assessments, and national defense strategies. To keep pace with defense capability requirements, the CBD Program (CBDP), as part of its mission, routinely promulgates chemical and biological research. The comprehensive research program encompasses both intramural and extramural sources, and the role of each is vital to the fulfillment of the CBDP objectives.

DTRA is seeking optimum approaches to meet technology objectives with a goal to identify and select science and technology projects that can be transitioned to joint acquisition programs.

Attachments

Files listed on SAM.gov. The ones we hold a copy of download from here; the rest open SAM's download, which needs no account.

The contract, on USAspending

Federal procurement data the awarding office reported to FPDS, matched to this solicitation by its number.

UEI
GMK2EG5EDNL7
CAGE
1TE69
Vendor location
Austin, TX
Contract
HDTRA124C0039, definitive contract
Obligated
$2,609,140.92, current value $2,709,141, potential $4,647,687
Actions
8 between September 23, 2024 and June 4, 2026
Competition
Full and Open Competition, 1 offer received
Set-aside reported
No Set Aside Used.
Described as
Functional Exploitation and Analysis of Threats (Feat)
Match
solicitation number HDTRA122S0002 equals the FPDS solicitation identifier; same awarding office HDTRA1 (high confidence)
UEI
JAXJSTJJSP74
CAGE
3U6L5
Vendor location
Cambridge, MA
Contract
HDTRA125C0002, definitive contract
Obligated
$3,554,029.10, current value $3,954,029, potential $4,930,264
Actions
7 between October 9, 2024 and April 14, 2026
Competition
Full and Open Competition, 1 offer received
Set-aside reported
No Set Aside Used.
Described as
Real-Time Analysis of Biosecurity Threats from Sequencing (Rabits)
Match
solicitation number HDTRA122S0002 equals the FPDS solicitation identifier; same awarding office HDTRA1 (high confidence)
UEI
SN7KD2UK7GC5
CAGE
1WEZ6
Vendor location
Winston Salem, NC
Contract
HDTRA125C0003, definitive contract
Obligated
$1,040,378.45, current value $1,241,378, potential $1,787,805
Actions
5 between February 18, 2025 and March 19, 2026
Competition
Full and Open Competition, 1 offer received
Set-aside reported
No Set Aside Used.
Described as
Identification of Tear Biomarkers as Broad-Spectrum Readouts of Chemical Injury
Match
solicitation number HDTRA122S0002 equals the FPDS solicitation identifier; same awarding office HDTRA1 (high confidence)
Recipient
Aeris LLC
UEI
TNMKZL4WJL79
CAGE
7C7P2
Vendor location
Louisville, CO
Contract
HDTRA125C0004, definitive contract
Obligated
$2,839,876.00, potential $5,596,490
Actions
6 between February 5, 2025 and May 12, 2026
Competition
Full and Open Competition, 1 offer received
Set-aside reported
No Set Aside Used.
Described as
Next Generation Multi-Scale Chemical and Biological Hazard Transport and Dispersion Model
Match
solicitation number HDTRA122S0002 equals the FPDS solicitation identifier; same awarding office HDTRA1 (high confidence)
Recipient
Aeris LLC
UEI
TNMKZL4WJL79
CAGE
7C7P2
Vendor location
Louisville, CO
Contract
HDTRA125C0005, definitive contract
Obligated
$3,161,369.00, potential $4,348,990
Actions
9 between December 3, 2024 and May 12, 2026
Competition
Full and Open Competition After Exclusion of Sources, 7 offers received
Set-aside reported
Small Business Set Aside - Total
Described as
Multi Echelon Tactical Operational Response (Mentor)
Match
solicitation number HDTRA122S0002 equals the FPDS solicitation identifier; same awarding office HDTRA1 (high confidence)
Recipient
Aeris LLC
UEI
TNMKZL4WJL79
CAGE
7C7P2
Vendor location
Louisville, CO
Contract
HDTRA125CE006, definitive contract
Obligated
$2,175,989.10, potential $11,600,923
Actions
4 between September 30, 2025 and May 6, 2026
Competition
Full and Open Competition, 3 offers received
Set-aside reported
No Set Aside Used.
Described as
Develop a Digital Twin System for Chemical and Biological Sensors That Will Enhance Training, Situational Awareness, Operational Efficiency, and Comprehensive Understanding and Assessment in Cb-Contested Environments.
Match
solicitation number HDTRA122S0002 equals the FPDS solicitation identifier; same awarding office HDTRA1 (high confidence)
UEI
LTMGBJ76B9D8
CAGE
9R446
Vendor location
Albuquerque, NM
Contract
HDTRA125CE014, definitive contract
Obligated
$1,272,712.00, potential $7,960,961
Actions
3 between September 30, 2025 and May 6, 2026
Competition
Full and Open Competition, 3 offers received
Set-aside reported
No Set Aside Used.
Described as
Digital Twin for Chemical and Biological Sensors - from Proof-Of-Concept to Operational Twins
Match
solicitation number HDTRA122S0002 equals the FPDS solicitation identifier; same awarding office HDTRA1 (high confidence)
Recipient
Netrias, LLC
UEI
HC4YMJZ9X9P3
CAGE
7CAF6
Vendor location
Annapolis, MD
Contract
HDTRA126C0003, definitive contract
Obligated
$1,300,000.00, current value $3,548,292, potential $9,549,878
Actions
1 between June 2, 2026 and June 2, 2026
Competition
Full and Open Competition, 10 offers received
Set-aside reported
No Set Aside Used.
Described as
Pathogen Agnostic Platform for Harmonizing and Evaluating Multi-Omics Knowledge
Match
solicitation number HDTRA122S0002 equals the FPDS solicitation identifier; same awarding office HDTRA1 (high confidence)

Publications

Every notice SAM.gov issued under this solicitation number, oldest first. Each is a separate record on SAM.

  1. April 1, 2024

    Solicitation

    Due August 16, 2022 at 2:00 PM EDT. SAM.gov, notice b4682a86a0ae4faa91d7e2c16b06cd57

    20 revisions on SAM
    • August 25, 2026: publish, solicitation
    • July 8, 2026: publish, solicitation
    • August 20, 2025: publish, solicitation
    • March 11, 2025: publish, solicitation
    • February 13, 2025: publish, solicitation
    • August 30, 2024: publish, solicitation
    • June 6, 2024: publish, solicitation
    • May 10, 2024: publish, solicitation
    • April 30, 2024: publish, solicitation
    • April 1, 2024: publish, solicitation
    • September 29, 2023: publish, solicitation
    • September 6, 2023: publish, solicitation
    • September 6, 2023: publish, solicitation
    • September 6, 2023: publish, solicitation
    • August 14, 2023: publish, solicitation
    • April 24, 2023: publish, solicitation
    • March 21, 2023: publish, solicitation
    • November 10, 2022: publish, solicitation
    • May 9, 2022: publish, presolicitation
    • June 22, 2022: publish, solicitation
  2. April 30, 2024

    Solicitation

    Due August 16, 2022 at 2:00 PM EDT. SAM.gov, notice ae3915eeb0fd42d5ba41380faa8b2f40

    20 revisions on SAM
    • August 25, 2026: publish, solicitation
    • July 8, 2026: publish, solicitation
    • August 20, 2025: publish, solicitation
    • March 11, 2025: publish, solicitation
    • February 13, 2025: publish, solicitation
    • August 30, 2024: publish, solicitation
    • June 6, 2024: publish, solicitation
    • May 10, 2024: publish, solicitation
    • April 30, 2024: publish, solicitation
    • April 1, 2024: publish, solicitation
    • September 29, 2023: publish, solicitation
    • September 6, 2023: publish, solicitation
    • September 6, 2023: publish, solicitation
    • September 6, 2023: publish, solicitation
    • August 14, 2023: publish, solicitation
    • April 24, 2023: publish, solicitation
    • March 21, 2023: publish, solicitation
    • November 10, 2022: publish, solicitation
    • May 9, 2022: publish, presolicitation
    • June 22, 2022: publish, solicitation
  3. May 10, 2024

    Solicitation

    Due August 16, 2022 at 2:00 PM EDT. SAM.gov, notice 83294ea428b547d58c081359fa192c9d

    20 revisions on SAM
    • August 25, 2026: publish, solicitation
    • July 8, 2026: publish, solicitation
    • August 20, 2025: publish, solicitation
    • March 11, 2025: publish, solicitation
    • February 13, 2025: publish, solicitation
    • August 30, 2024: publish, solicitation
    • June 6, 2024: publish, solicitation
    • May 10, 2024: publish, solicitation
    • April 30, 2024: publish, solicitation
    • April 1, 2024: publish, solicitation
    • September 29, 2023: publish, solicitation
    • September 6, 2023: publish, solicitation
    • September 6, 2023: publish, solicitation
    • September 6, 2023: publish, solicitation
    • August 14, 2023: publish, solicitation
    • April 24, 2023: publish, solicitation
    • March 21, 2023: publish, solicitation
    • November 10, 2022: publish, solicitation
    • May 9, 2022: publish, presolicitation
    • June 22, 2022: publish, solicitation
  4. June 6, 2024

    Solicitation

    Due August 16, 2022 at 2:00 PM EDT. SAM.gov, notice e55fc2d014b24061ac3d5db74f627b33

    20 revisions on SAM
    • August 25, 2026: publish, solicitation
    • July 8, 2026: publish, solicitation
    • August 20, 2025: publish, solicitation
    • March 11, 2025: publish, solicitation
    • February 13, 2025: publish, solicitation
    • August 30, 2024: publish, solicitation
    • June 6, 2024: publish, solicitation
    • May 10, 2024: publish, solicitation
    • April 30, 2024: publish, solicitation
    • April 1, 2024: publish, solicitation
    • September 29, 2023: publish, solicitation
    • September 6, 2023: publish, solicitation
    • September 6, 2023: publish, solicitation
    • September 6, 2023: publish, solicitation
    • August 14, 2023: publish, solicitation
    • April 24, 2023: publish, solicitation
    • March 21, 2023: publish, solicitation
    • November 10, 2022: publish, solicitation
    • May 9, 2022: publish, presolicitation
    • June 22, 2022: publish, solicitation
  5. August 30, 2024

    Solicitation

    Due August 16, 2022 at 2:00 PM EDT. SAM.gov, notice 6308648904b64524b0cf37259396e38e

    20 revisions on SAM
    • August 25, 2026: publish, solicitation
    • July 8, 2026: publish, solicitation
    • August 20, 2025: publish, solicitation
    • March 11, 2025: publish, solicitation
    • February 13, 2025: publish, solicitation
    • August 30, 2024: publish, solicitation
    • June 6, 2024: publish, solicitation
    • May 10, 2024: publish, solicitation
    • April 30, 2024: publish, solicitation
    • April 1, 2024: publish, solicitation
    • September 29, 2023: publish, solicitation
    • September 6, 2023: publish, solicitation
    • September 6, 2023: publish, solicitation
    • September 6, 2023: publish, solicitation
    • August 14, 2023: publish, solicitation
    • April 24, 2023: publish, solicitation
    • March 21, 2023: publish, solicitation
    • November 10, 2022: publish, solicitation
    • May 9, 2022: publish, presolicitation
    • June 22, 2022: publish, solicitation
  6. February 13, 2025

    Solicitation

    Due August 16, 2022 at 2:00 PM EDT. SAM.gov, notice a6906d657a0e4e9e829be4b82c1acb4a

    20 revisions on SAM
    • August 25, 2026: publish, solicitation
    • July 8, 2026: publish, solicitation
    • August 20, 2025: publish, solicitation
    • March 11, 2025: publish, solicitation
    • February 13, 2025: publish, solicitation
    • August 30, 2024: publish, solicitation
    • June 6, 2024: publish, solicitation
    • May 10, 2024: publish, solicitation
    • April 30, 2024: publish, solicitation
    • April 1, 2024: publish, solicitation
    • September 29, 2023: publish, solicitation
    • September 6, 2023: publish, solicitation
    • September 6, 2023: publish, solicitation
    • September 6, 2023: publish, solicitation
    • August 14, 2023: publish, solicitation
    • April 24, 2023: publish, solicitation
    • March 21, 2023: publish, solicitation
    • November 10, 2022: publish, solicitation
    • May 9, 2022: publish, presolicitation
    • June 22, 2022: publish, solicitation
  7. March 11, 2025

    Solicitation

    Due August 16, 2022 at 2:00 PM EDT. SAM.gov, notice 44c79599f5fb4efa8f75742f4a752438

    21 revisions on SAM
    • August 25, 2026: publish, solicitation
    • July 8, 2026: publish, solicitation
    • August 20, 2025: publish, solicitation
    • May 27, 2025: publish, award notice
    • March 11, 2025: publish, solicitation
    • February 13, 2025: publish, solicitation
    • August 30, 2024: publish, solicitation
    • June 6, 2024: publish, solicitation
    • May 10, 2024: publish, solicitation
    • April 30, 2024: publish, solicitation
    • April 1, 2024: publish, solicitation
    • September 29, 2023: publish, solicitation
    • September 6, 2023: publish, solicitation
    • September 6, 2023: publish, solicitation
    • September 6, 2023: publish, solicitation
    • August 14, 2023: publish, solicitation
    • April 24, 2023: publish, solicitation
    • March 21, 2023: publish, solicitation
    • November 10, 2022: publish, solicitation
    • May 9, 2022: publish, presolicitation
    • June 22, 2022: publish, solicitation
  8. August 20, 2025

    Solicitation

    Due August 16, 2022 at 2:00 PM EDT. SAM.gov, notice 52e119b3ee594efc9565d5baac30fcbb

    23 revisions on SAM
    • August 25, 2026: publish, solicitation
    • July 8, 2026: publish, solicitation
    • June 3, 2026: publish, award notice
    • September 30, 2025: publish, award notice
    • October 2, 2025: publish, award notice
    • August 20, 2025: publish, solicitation
    • March 11, 2025: publish, solicitation
    • February 13, 2025: publish, solicitation
    • August 30, 2024: publish, solicitation
    • June 6, 2024: publish, solicitation
    • May 10, 2024: publish, solicitation
    • April 30, 2024: publish, solicitation
    • April 1, 2024: publish, solicitation
    • September 29, 2023: publish, solicitation
    • September 6, 2023: publish, solicitation
    • September 6, 2023: publish, solicitation
    • September 6, 2023: publish, solicitation
    • August 14, 2023: publish, solicitation
    • April 24, 2023: publish, solicitation
    • March 21, 2023: publish, solicitation
    • November 10, 2022: publish, solicitation
    • May 9, 2022: publish, presolicitation
    • June 22, 2022: publish, solicitation
  9. July 8, 2026

    Solicitation

    Due August 16, 2022 at 2:00 PM EDT. SAM.gov, notice b7efc074f8814d3ab3e85ac5dc989603

    20 revisions on SAM
    • August 25, 2026: publish, solicitation
    • July 8, 2026: publish, solicitation
    • August 20, 2025: publish, solicitation
    • March 11, 2025: publish, solicitation
    • February 13, 2025: publish, solicitation
    • August 30, 2024: publish, solicitation
    • June 6, 2024: publish, solicitation
    • May 10, 2024: publish, solicitation
    • April 30, 2024: publish, solicitation
    • April 1, 2024: publish, solicitation
    • September 29, 2023: publish, solicitation
    • September 6, 2023: publish, solicitation
    • September 6, 2023: publish, solicitation
    • September 6, 2023: publish, solicitation
    • August 14, 2023: publish, solicitation
    • April 24, 2023: publish, solicitation
    • March 21, 2023: publish, solicitation
    • November 10, 2022: publish, solicitation
    • May 9, 2022: publish, presolicitation
    • June 22, 2022: publish, solicitation
  10. August 25, 2026

    Solicitation

    Due August 16, 2022 at 2:00 PM EDT. SAM.gov, notice cd4bccea69604861bb4953fc582bc24a

    20 revisions on SAM
    • August 25, 2026: publish, solicitation
    • July 8, 2026: publish, solicitation
    • August 20, 2025: publish, solicitation
    • March 11, 2025: publish, solicitation
    • February 13, 2025: publish, solicitation
    • August 30, 2024: publish, solicitation
    • June 6, 2024: publish, solicitation
    • May 10, 2024: publish, solicitation
    • April 30, 2024: publish, solicitation
    • April 1, 2024: publish, solicitation
    • September 29, 2023: publish, solicitation
    • September 6, 2023: publish, solicitation
    • September 6, 2023: publish, solicitation
    • September 6, 2023: publish, solicitation
    • August 14, 2023: publish, solicitation
    • April 24, 2023: publish, solicitation
    • March 21, 2023: publish, solicitation
    • November 10, 2022: publish, solicitation
    • May 9, 2022: publish, presolicitation
    • June 22, 2022: publish, solicitation

Points of contact