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Solicitation

Technology InteGrator and AcceleratoR (TIGAR)

ARPA-H-SOL-26-144

National Institutes of Health, Advanced Research Projects Agency for Health (Arpa-H). Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology).

Offers due

December 8, 2026 at 5:00 PM EST

37 days from now. Posted July 13, 2026, first published April 22, 2026.

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Similar, open now

All 126 open in research and development in the physical, engineering, and life sciences (except nanotechnology and biotechnology)

Description

As published on SAM.gov.

Amendment 4

The ISO was updated to extend the Solution Video submission deadline to August 12, 2026 and the Full Proposal submission deadline to September 17, 2026 for intake Group 1. See page 3 of the full text ISO for more information.

Amendment 3

(1) Appendix B was updated to remove track changes

(2) Appendix C4 was updated to remove an erroneous comment. 

Amendment 2

(1) Instructions on how to submit a Solution Video were added to the ISO (see pages 7-8).

(2) Information related to the Video Captions file was added to Appendix B.0 (Solution Video Format and Instructions). 

(3) The instructions in Appendix B.1 (Template for Supplemental Slides) were simplified, and a Cost Summary slide was added (see Slide 7).  

(4) Appendix C.3 was updated to reference "Phase" rather than "Year" for clarity. 

(5) The Administation and National Policy document in Appendix C.4 was replaced with an updated document. 

Amendment 1

The ISO was updated with the new webinar and webinar registration dates. 

Effort Description:

TIGAR Exploratory Topic will forge entirely new paths to stabilizing regenerative tissues and organs by seeding the development of enabling technologies that can unlock temperature-flexible storage in increasingly larger and more complex biological systems. Solutions may involve any combination of new materials, artificial intelligence/machine learning, high-throughput screening methods, biological interventions, devices, processing methods, analytical technology, and packaging approaches that can overcome current roadblocks and yield a leap in the ability to store and distribute complex biologics, without introducing high cost or complexity. Strategies that reduce reliance on strictly controlled temperature zones and can ensure safe storage in a range of environmental conditions are preferred. While long-term temperature-flexible storage is ideal, any advance that removes logistical hurdles or establishes shelf-life stability at easy to maintain temperatures (preferably non-cryogenic) will be considered. Innovations at the cellular level without a strategy for deployment in thick tissues will not be considered. 

Please ensure to follow this opportunity for any updates.

For more information on the TIGAR Exploratory Topic visit: https://arpa-h.gov/explore-funding/initiatives-and-sprints/tigar

For information on Proposer's Day details and registration information, please see Special Notice ARPA-H-SN-26-142

Attachments

Files listed on SAM.gov. The ones we hold a copy of download from here; the rest open SAM's download, which needs no account.

Publications

Every notice SAM.gov issued under this solicitation number, oldest first. Each is a separate record on SAM.

  1. April 22, 2026

    Solicitation

    Due June 8, 2026 at 5:00 PM EDT. SAM.gov, notice 1f00659d66004c7d8d3027793e60ff28

    8 revisions on SAM
    • July 13, 2026: publish, solicitation
    • July 6, 2026: publish, solicitation
    • July 6, 2026: publish, solicitation
    • June 1, 2026: publish, solicitation
    • May 14, 2026: publish, solicitation
    • April 24, 2026: publish, solicitation
    • April 22, 2026: publish, special notice
    • April 22, 2026: publish, solicitation
  2. April 24, 2026

    Solicitation

    Due June 8, 2026 at 5:00 PM EDT. SAM.gov, notice 267fe8f6358f495c9454135b19b2083e

    7 revisions on SAM
    • July 13, 2026: publish, solicitation
    • July 6, 2026: publish, solicitation
    • July 6, 2026: publish, solicitation
    • June 1, 2026: publish, solicitation
    • May 14, 2026: publish, solicitation
    • April 24, 2026: publish, solicitation
    • April 22, 2026: publish, solicitation
  3. May 14, 2026

    Solicitation

    Due June 8, 2026 at 5:00 PM EDT. SAM.gov, notice 64878caa585841f88945f36e44ea75e3

    7 revisions on SAM
    • July 13, 2026: publish, solicitation
    • July 6, 2026: publish, solicitation
    • July 6, 2026: publish, solicitation
    • June 1, 2026: publish, solicitation
    • May 14, 2026: publish, solicitation
    • April 24, 2026: publish, solicitation
    • April 22, 2026: publish, solicitation
  4. June 1, 2026

    Solicitation

    Due June 8, 2026 at 5:00 PM EDT. SAM.gov, notice c662d00ba2ff43afab13be078d3e42d0

    7 revisions on SAM
    • July 13, 2026: publish, solicitation
    • July 6, 2026: publish, solicitation
    • July 6, 2026: publish, solicitation
    • June 1, 2026: publish, solicitation
    • May 14, 2026: publish, solicitation
    • April 24, 2026: publish, solicitation
    • April 22, 2026: publish, solicitation
  5. July 6, 2026

    Solicitation

    Due December 8, 2026 at 5:00 PM EST. SAM.gov, notice 56326303c136466388706de839ffc00e

    7 revisions on SAM
    • July 13, 2026: publish, solicitation
    • July 6, 2026: publish, solicitation
    • July 6, 2026: publish, solicitation
    • June 1, 2026: publish, solicitation
    • May 14, 2026: publish, solicitation
    • April 24, 2026: publish, solicitation
    • April 22, 2026: publish, solicitation
  6. July 6, 2026

    Solicitation

    Due June 8, 2026 at 5:00 PM EDT. SAM.gov, notice 7979a7b2edbd42638c9927f88d4be448

    7 revisions on SAM
    • July 13, 2026: publish, solicitation
    • July 6, 2026: publish, solicitation
    • July 6, 2026: publish, solicitation
    • June 1, 2026: publish, solicitation
    • May 14, 2026: publish, solicitation
    • April 24, 2026: publish, solicitation
    • April 22, 2026: publish, solicitation
  7. July 13, 2026

    Solicitation

    Due December 8, 2026 at 5:00 PM EST. SAM.gov, notice 88bdb5f63faa47358ff4dc563c766bf4

    7 revisions on SAM
    • July 13, 2026: publish, solicitation
    • July 6, 2026: publish, solicitation
    • July 6, 2026: publish, solicitation
    • June 1, 2026: publish, solicitation
    • May 14, 2026: publish, solicitation
    • April 24, 2026: publish, solicitation
    • April 22, 2026: publish, solicitation

Points of contact