GENETIC MEDICINES AND INDIVIDUALIZED MANUFACTURING FOR EVERYONE (GIVE)

October 03, 2025:

1. Special Notice (ARPA-H-SN-26-140) posted to SAM.GOV.
2. GIVE ISO (ARPA-H-SOL-25-129) Amendment 01 posted.
   For details, please see the Summary of Changes (pg 2) in the attached (GIVE_ISO_Amend_01_ 20251003).

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September 25, 2025:

The Advanced Research Projects Agency for Health (ARPA-H) Genetic Medicines And Individualized Manufacturing For Everyone (GIVE) Program aims to accelerate biomanufacturing equipment and process innovation, digital transformation, next generation therapies, and commercial adoption all at once focused on accelerating innovation in the manufacture, testing, and release of RNA-containing modalities. GIVE seeks to harness human-machine collaboration, eliminate scale-up costs, and drive toward a fundamentally different future state – a state where biomanufacturing is localized, accessible, and individualized.

Interested parties are invited to review the attached GIVE Innovative Solutions Opening (ISO) ARPA-H -SOL-25-129. 

Solution summaries are due December 19, 2025, 5:00 PM ET.
A solution summary must be submitted to submit a proposal. Submissions must be made to:

• Solution Summary Submission Site: https://solutions.arpa-h.gov/Submit-Solution/

Please ensure to follow this opportunity for any updates.
For more information on the GIVE program visit: https://arpa-h.gov/explore-funding/programs/give