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Presolicitation

Whole Exome Analysis of NIAAA Clinical Center pATIENTS

75N98026Q00677

National Institutes of Health, National Institutes of Health Olao. Biological Product (except Diagnostic) Manufacturing.

1 open like this View on SAM.gov Markdown

Response deadline

July 2, 2026 at 9:00 AM EDT

Closed 121 days ago. Posted June 22, 2026. Scheduled to archive July 3, 2026.

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This one closed in 2026

1 like it is open now in biological product (except diagnostic) manufacturing

Description

As published on SAM.gov.

The NIAAA Clinical Center patient cohort has been analyzed patients for sequence variant differences, and changes in response to treatment over the course of many years as part of an effort to identify underlying causes of alcohol related disorders. Analysis has previously been performed on over 2000 patients using the AmpliSeq Exome enrichment system and sequenced on the ION sequencing platform because it provides the capability of cost-effective high throughput whole-exome genome-wide analysis. The use of a single enrichment and sequencing platform with consistent information content is essential for analysis of samples screened at different times and it is therefore imperative for analytical integrity that all samples in the study are processed on the same sequencing platform, as each platform has a unique pattern of error

Attachments

Files listed on SAM.gov. The ones we hold a copy of download from here; the rest open SAM's download, which needs no account.

Publications

Every notice SAM.gov issued under this solicitation number, oldest first. Each is a separate record on SAM.

  1. June 22, 2026

    Presolicitation

    Due July 2, 2026 at 9:00 AM EDT. SAM.gov, notice aa04d360a0034c6cbe4e2bae2a6f17c2

    1 revisions on SAM
    • June 22, 2026: publish, presolicitation

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