Scientific Management and Support to the National Institute of Mental Health (NIMH) Repository and Genomics Resource (NRGR)

SEE ATTACHED AMENDMENT TWO TO EXTEND THE PROPOSAL DUE DATE AND PROVIDE ANSWERS TO QUESTIONS. SEE ATTACHED AMENDMENT ONE TO EXTEND THE PROPOSAL DUE DATE. The National Institute of Mental Health Repository and Genomics Resource (NRGR) is a centralized national biorepository funded by the National Institutes of Health (NIH). NRGR provides to the research community DNA, RNA, cell lines, and other biospecimens from large collections of individuals with psychiatric illness along with neurotypical controls.

NRGR provides basic demographic and diagnostic data for all biospecimens and genotype, DNA sequence, and gene expression data associated with a subset of biospecimens. The purpose of this acquisition is to obtain services to sustain, enhance, and enrich NRGR for genetic and cellular studies of psychiatric disorders to facilitate and accelerate the scientific understanding of the genetic risk architecture and basic biology underlying mental disorders.

This effort is expected to involve a functionally integrated, multi-disciplinary team that will continue to manage broad sharing of biospecimens and data resources through a single, centralized, national resource to advance basic and translational research in the genetics of mental disorders.