Solicitation
Resilient Systems Office (RSO) Mission Office Innovative Solutions Opening (ISO)
ARPA-H-SOL-24-103
National Institutes of Health, Advanced Research Projects Agency for Health (Arpa-H). Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology).
Offers due
March 5, 2029 at 11:59 PM EST
901 days from now. Posted January 8, 2026, first published March 14, 2024.
Description
As published on SAM.gov.
This ISO seeks solution summary and proposal submissions for projects that fall within the scope of the ARPA-H mission Resilient Systems Office (RSO). RSO’s interest areas will address systemic challenges across the healthcare and public health landscape by investing in cutting-edge technologies that address long-standing gaps in the quality, efficacy, and consistent availability of care. Solution summary submissions must be submitted to:
https://solutions.arpa-h.gov Questions must be submitted to:
https://solutions.arpa-h.gov/Ask-A-Question/ Proposal submission should be submitted to:
https://solutions.arpa-h.gov/Submit-Proposal/ Amendment 3 is effective immediately; however, if an entity has previously submitted a solution summary and/or a proposal, the prior solicitation(s) will be followed for those submissions. If a solution summary is submitted; however, a proposal has not been submitted yet, the proposal will be evaluated in accordance with this amendment. The following updates were made to the proposal documents:
1) Administrative & National Policy Requirements Document Updated the instructions and references within the “Organizational Conflicts of Interest (OCI) Affirmations and Disclosure” section. Updated questions, instructions, and content within the “Research Security Disclosure” section. Updated the instructions and intellectual property data assertions charts within the “IP” section.
This included providing definitions of rights categories (unlimited, government purpose, limited, and specially negotiated/other) and consolidating two data assertions charts into one to assist proposers more efficiently complete the document. Specifically, the “Non-Commercial” and “Commercial” tables were removed and replaced with the “Background IP and Data Assertions” table. Eliminated the “Software Component Standards” section. Updated the Human Subjects Research (HSR) table within the “HSR” section. Updated the Animal Subjects Research (ASR) table within the “ASR” section. Updated the questions and instructions within the “Biosecurity” section.
2) Cost Proposal Document (Word document) Updated the instructions within the “Level of Effort and Labor Costs” section. Added definitions for “burdened labor rate” and “fully burdened labor rate” to provide clarity for proposers when completing the document. Also added a statement to clarify that fully burdened labor rates are not used in the Cost Proposal Workbooks. Increased the threshold for proposers to provide supporting documentation with their proposal for planned materials and equipment purchases based on unit cost. The unit cost threshold was increased from $5,000 to $10,000.
3) Cost Proposal Workbooks (Excel spreadsheets) Updated instructions to clarify that ARPA-H will assume profit/fee is not applicable for proposals if proposers do not include profit/fee in the workbook. Updated the instructions for supporting documentation associated with planned materials and equipment purchases (based on the unit cost threshold increasing from $5,000 to $10,000). Completed administrative update to a tab
Publications
Every notice SAM.gov issued under this solicitation number, oldest first. Each is a separate record on SAM.
March 14, 2024
Solicitation
Office-Wide Innovative Solutions Opening for Resilient Systems Office (RSO)
Due March 15, 2025 at 5:00 PM EDT. SAM.gov, notice 76679cd8810f40229694c60c0a593302
May 2, 2024
Solicitation
Office-Wide Innovative Solutions Opening for Resilient Systems Office (RSO)
Due March 15, 2025 at 5:00 PM EDT. SAM.gov, notice 12060296542746d5a0845f26c43487bc
September 25, 2024
Solicitation
Office-Wide Innovative Solutions Opening for Resilient Systems Office (RSO)
Due March 3, 2029 at 11:59 PM EST. SAM.gov, notice 3b131b790c8f4607b3c7214b93156018
September 25, 2024
Solicitation
Office-Wide Innovative Solutions Opening for Resilient Systems Office (RSO)
Due March 3, 2029 at 11:59 PM EST. SAM.gov, notice ecbf2716b6e648e69dd2eec1a79ab027
June 6, 2025
Solicitation
Due March 5, 2029 at 11:59 PM EST. SAM.gov, notice c575f73500844322be760e0d98c233ac
October 14, 2025
Solicitation
Due March 5, 2029 at 11:59 PM EST. SAM.gov, notice 2fe82425541c4b6f92713d9812721be4
October 14, 2025
Solicitation
Due March 5, 2029 at 11:59 PM EST. SAM.gov, notice 36eb58892e1f49f897c81d87ff7a95fe
November 13, 2025
Solicitation
Due March 5, 2029 at 11:59 PM EST. SAM.gov, notice afb42f0cb40041baa180f7413ba2f7b1
January 8, 2026
Solicitation
Due March 5, 2029 at 11:59 PM EST. SAM.gov, notice 2d1209273c284cb48ea9898939f7c3f8
Points of contact
- SEE DESCRIPTION SECTIONdo_NOT_use_THIS_email_ADDRESS@arpa-h.gov
Also open from this buyer
- Advanced Research Projects Agency for Health (ARPA-H) Small Business Innovation Research (SBIR)/Small Business Technology Transfer (STTR) ProgramPresolicitationSmall businessNAICS 541715Washington, DC7599226SN106Closes in 14 daysOct 1
- Restorative and health-Enhancing Sleep Time (REST)SolicitationNAICS 541715ARPA-H-SOL-26-159Closes in 26 daysOct 13
- Fast Assessment of Solutions, Therapeutics, Pharmaceuticals, and SupplieS (FASTPASS) Innovative Solutions OpeningSolicitationNAICS 541715District of ColumbiaARPA-H-SOL-26-160Closes in 54 daysNov 10
- Technology InteGrator and AcceleratoR (TIGAR)SolicitationNAICS 541715Washington, DCARPA-H-SOL-26-144Closes in 82 daysDec 8
- ARPA-H Emerging Health Innovators (EHI) Initiative Proposers DaySolicitationNAICS 541714District of ColumbiaARPA-H-SOL-26-150Closes in 146 daysFeb 10, 2027