Notice to Intent Sole Source - PromethION 2 Integrated

This is a Notice of Intent, not a request for proposal. The National Institute of Health, Clinical Center (NIH-CC) intends to negotiate on an other than full and open competition basis with the following vendor: Government Scientific Source. The purpose of this procurement is to secure the instrument and reagents for the Oxford Nanopore PromethION 2 Integrated long read sequencing assay for testing samples from patient.

Oxford Nanopore PromethION 2 Integrated instrument and assay are used to perform long read genomic DNA sequencing of patient samples to detect DNA mutations, DNA structural abnormalities (e.g., deletions, insertions, and inversions, etc.), and DNA methylation that are often undetected by commonly used DNA sequencing techniques. Government Scientific Source is a third-party distributor of Oxford Nanopore products.

It is therefore deemed to be in the best interest of clinical research and patient care and in Government’s best interest that this agreement is approved. The statutory authority for this sole source requirement is 41 U.S.C. 253(c) (1) as implemented by FAR 6.302-1 only one responsible source and no other supply of service will satisfy agency requirements. THIS IS NOT A REQUEST FOR PROPOSAL.

All responsible sources that could provide the required may submit a capability statement that will be considered by email (subject line to reference NOI-CC-256-002719) by 12:00 PM eastern standard time on 02/21/2026 to:

valerie.gregorio@nih.gov. All responses received by the closing date of this synopsis will be considered by the Government. A determination not to compete this requirement, based upon responses to this notice, is solely within the discretion of the Government.