NOI - Acquisition of a Sonication Device for Amyloid Seeding Experiments

The National Heart, Lung, and Blood Institute (NHLBI) intends to award a sole source purchase order to Hologic Sales and Service, LLC for the acquisition of a sonication device to support amyloid seeding experiments. The required system must provide highly controlled, reproducible sonication of small-volume biological samples to enable standardized preparation of pre-formed fibrils (PFFs), which are critical for ongoing research into neurodegenerative diseases.

This notice of intent is not a request for competitive quotations; however, interested parties may submit a capability statement demonstrating their ability to meet all minimum technical requirements, including controlled cavitation, sealed-tube processing, continuous sample rotation, and validated reproducibility for PFF generation.