Maintenance/Repair service agreement for Amnis CellStream Flow Cytometry System

This is a Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding the availability and capability of all qualified sources to perform a potential requirement.

This notice is issued to help determine the availability of qualified companies technically capable of meeting the Government requirement, to determine the method of acquisition, and availability of domestic sources manufactured in the United States in sufficient and reasonably available commercial quantities and of a satisfactory quality. It is not to be construed as a commitment by the Government to issue a solicitation or ultimately award a contract. Responses will not be considered as proposals or quotes.

No award will be made as a result of this notice. The Government will NOT be responsible for any costs incurred by the respondents to this notice. This notice is strictly for research and information purposes only. Small businesses are encouraged to respond. For equipment/supply requirements, responses must include the place of manufacturing (i.e. address if supply/equipment is a domestic end product and include country of manufacture).

For equipment/supply requirements, small businesses must also address the size status of the manufacturer under the applicable NAICS code (i.e. address Non-Manufacturer Rule).

Background: The National Institutes of Health (NIH) is an agency of the Department of Health and Human Services and the Federal focal point for health research. Its mission is to seek fundamental knowledge about the nature and behavior of living systems and apply that knowledge to enhance health, lengthen life, and reduce illness and disability.

The National Institute of Neurological Disorders and Stroke (NINDS) is a part of the National Institutes of Health (NIH), The Inherited Movement Disorders Unit (IMDU) focuses on mitochondrial dysfunction in genetic forms of Parkinson’s disease. To date, the IMDU researchers have investigated the roles of specific mitochondrial proteins (including Parkin, PINK1, CHCHD2, and CHCHD10) which cause neurodegeneration when mutated.

This is for a service contract to keep operational a benchtop flow cytometer with a high sensitivity detector that allows analysis of aspect ratio, size, and fluorescent intensity of cells and isolated mitochondria in a 96 well format, at a high flow rate (up to 20,000 events/s) in order to determine the effect of Parkinson’s disease-causing genes on mitochondrial function, consistent with the mission of the Inherited Movement Disorders Unit.