{"canonical":"https://abierto.us/opportunities/panmra24p0000004380","key":"PANMRA24P0000004380","url":"https://abierto.us/opportunities/panmra24p0000004380","title":"Shank 2 Cryorecovery Support Services for the Medical Readiness System Biology (MRSB) at WRAIR","solicitation_number":"PANMRA24P0000-004380","notice_type":"s","open":false,"response_deadline":"2024-06-14T14:00:00Z","first_posted":"2024-05-31","last_posted":"2024-07-22","department":"DEPT OF DEFENSE","subagency":"DEFENSE HEALTH AGENCY (DHA)","office":"ARMY MED RES ACQ ACTIVITY","naics":"621511","psc":"AN12","set_aside":null,"place_state":"MD","place_county":"24031","place_county_name":"Montgomery County","place_city":"2472450","place_city_name":"Silver Spring","winner":null,"award_amount":null,"publications":[{"notice_id":"4077f1ecdd2042ccb21f2936a95fb041","title":"Shank 2 Cryorecovery Support Services for the Medical Readiness System Biology (MRSB) at WRAIR","solicitation_number":"PANMRA24P0000-004380","notice_type":"r","base_type":"r","posted":"2024-05-31","posted_at":null,"due_at":"2024-06-14T14:00:00Z","due_date":"2024-06-14","cancelled":null,"archived":null,"archive_date":"2024-08-15","award_number":null,"awardee_name":null,"amount":null,"link_sam":"https://sam.gov/workspace/contract/opp/4077f1ecdd2042ccb21f2936a95fb041/view","enriched":false,"history":[]},{"notice_id":"83eb70a6959c421b8ab867c01e4e4bba","title":"Shank 2 Cryorecovery Support Services for the Medical Readiness System Biology (MRSB) at WRAIR","solicitation_number":"PANMRA24P0000-004380","notice_type":"s","base_type":"r","posted":"2024-07-22","posted_at":null,"due_at":"2024-08-02T18:00:00Z","due_date":"2024-08-02","cancelled":null,"archived":null,"archive_date":"2024-09-15","award_number":null,"awardee_name":null,"amount":null,"link_sam":"https://sam.gov/workspace/contract/opp/83eb70a6959c421b8ab867c01e4e4bba/view","enriched":false,"history":[]}],"latest_notice_id":"83eb70a6959c421b8ab867c01e4e4bba","first_type":"r","notices":[{"dates":{"posted":"2024-05-31","response_deadline":{"raw":"2024-06-14T10:00:00-04:00","utc":"2024-06-14T14:00:00Z","date":"2024-06-14","time":"10:00:00","utc_offset_seconds":-14400}},"links":{"sam":"https://sam.gov/workspace/contract/opp/4077f1ecdd2042ccb21f2936a95fb041/view"},"naics":{"codes":["621511"],"primary":"621511"},"title":"Shank 2 Cryorecovery Support Services for the Medical Readiness System Biology (MRSB) at WRAIR","agency":{"office":{"code":"HT9425","name":"ARMY MED RES ACQ ACTIVITY"},"subtier":{"code":"97DH","name":"DEFENSE HEALTH AGENCY (DHA)"},"department":{"code":"097","name":"DEPT OF DEFENSE"},"office_address":{"zip":"21702","city":"FORT DETRICK","state":"MD","country":"USA"},"organization_type":"OFFICE"},"status":{"active":false,"archive_date":"2024-08-15","archive_type":"auto_custom"},"contacts":[{"name":"Brenda Mena","role":"primary","email":"brenda.i.mena.civ@health.mil"},{"name":"Jennifer Jackson","role":"secondary","email":"jennifer.c.jackson18.civ@health.mil"}],"base_type":{"code":"r","label":"Sources Sought"},"notice_id":"4077f1ecdd2042ccb21f2936a95fb041","provenance":{"extract":{"url":"https://s3.amazonaws.com/falextracts/Contract%20Opportunities/Archived%20Data/FY2024_archived_opportunities.csv","etag":"\"d582488fe153a9f11bf629913d176ffc-137\"","fetched_at":"2026-09-16T19:07:39.720164Z","row_sha256":"19d3bbf973ed2692e91c3d79ba74d1b5dd66229bed174210216ba43d202159af","last_modified":"2026-09-13T14:47:40Z"},"updated_at":"2026-09-16T19:07:39.720164Z","first_seen_at":"2026-09-16T19:07:39.720164Z"},"description":{"text":"Subject: Shank 2 Cryorecovery Support Services for the Medical Readiness System Biology (MRSB) at Walter Reed Army Institute of Research (WRAIR) THIS IS NOT A REQUEST FOR PROPOSALS (RFP) OR A REQUEST FOR QUOTATIONS (RFQ); IT IS STRICTLY A REQUEST FOR INFORMATION (RFI). NEITHER UNSOLICITED PROPOSALS NOR ANY OTHER KINDS OF OFFERS WILL BE CONSIDERED IN RESPONSE TO THIS RFI. NO CONTRACT WILL BE AWARDED PURSUANT TO THIS ANNOUNCEMENT. 1.0 DISCLAIMER: This RFI is issued solely for information and planning purposes and does not constitute a solicitation. Neither unsolicited proposals nor any other kind of offers will be considered in response to this RFI. Responses to this notice are not offers and will not be accepted by the Government to form a binding contract. Responders are solely responsible for all expenses associated with responding to this RFI. All information received in response to this RFI that is marked Proprietary will be handled accordingly. Responses to the RFI will not be returned. At this time, questions concerning the composition and requirements for a future RFQ will not be entertained. 2.0 SUBJECT: WRAIR is the largest and most diverse biomedical research laboratory in the Department of Defense (DoD). The main facility, the Daniel K. Inouye building, is located in Silver Spring, Maryland. Other laboratory and clinical facilities also carry out research studies in Asia, Africa, and Europe through cooperative partnerships with a host of other governments and militaries through the U.S. State Department. WRAIR’s greatest resources are the dedicated scientists, clinicians, and support personnel who make up the core of WRAIR today. By integrating basic research and advanced technology for the primary goal of protecting the Warfighter, WRAIR serves as the premier biomedical research organization within the DoD. 3.0 BACKGROUND: Medical Readiness Systems Biology (MRSB) - MRSB is a disease-agnostic program that utilizes high-throughput, multi-omics platforms supported by a suite of cutting edge, targeted assay tools and AI-driven analytical capabilities to identify diagnostic and prognostic biomarkers and generate a knowledge base about biological mechanisms and personalized care. MRSB is committed to developing a seamless, integrative module enabling to interrogate genome-to-phenome landscape to inform medical interventions and develop products to improve Warfighter health, performance, resilience, and readiness. The MRSB branch requires a specialized laboratory to perform Cryorecovery, custom breeding and cryopreservation on a specific genetic mouse line. MRSB currently has the sperm of this mouse line frozen and in storage. The contractor will be taking sperm and reviving the mouse line and then providing MRSB with mice of the specific genetic line as specifically requested. Additionally, the contractor will extract sperm and refreeze it down to allow this process to reoccur again in future research. 4.0 RESPONSE INSTRUCTIONS: Respondents should address the following in their capabilities statement: 1. Contractor must have genetically compatible female mice (C57BL/6J) to the cryopreserved sperm (strain Shank 2 Nestin-Cre) in possession by WRAIR. Any other will cause lengthy and costly delays in ongoing research at WRAIR. 2. Contractor must show they can create a mouse colony from cryopreserved sperm from 2 male Shank2 2 homozygous Nestin-Cre hemizygous mice provided by WRAIR. 3. See attachment 1 - Minimum Essential Characteristics (MECs) for more details. 5.0 CONTACT INFORMATION: All information regarding Capabilities Statements or any other proprietary information relative to this RFI shall be submitted via email to brenda.i.mena.civ@health.mil no later than 10:00 a.m. E.S.T. on 14 June 2024.","origin":"extract"},"notice_type":{"code":"r","label":"Sources Sought"},"schema_version":1,"solicitation_number":"PANMRA24P0000-004380","place_of_performance":{"zip":"20910","city":{"name":"Silver Spring"},"state":{"code":"MD"},"country":{"code":"USA"}},"product_service_code":"AN12"},{"dates":{"posted":"2024-07-22","response_deadline":{"raw":"2024-08-02T14:00:00-04:00","utc":"2024-08-02T18:00:00Z","date":"2024-08-02","time":"14:00:00","utc_offset_seconds":-14400}},"links":{"sam":"https://sam.gov/workspace/contract/opp/83eb70a6959c421b8ab867c01e4e4bba/view"},"naics":{"codes":["621511"],"primary":"621511"},"title":"Shank 2 Cryorecovery Support Services for the Medical Readiness System Biology (MRSB) at WRAIR","agency":{"office":{"code":"HT9425","name":"ARMY MED RES ACQ ACTIVITY"},"subtier":{"code":"97DH","name":"DEFENSE HEALTH AGENCY (DHA)"},"department":{"code":"097","name":"DEPT OF DEFENSE"},"office_address":{"zip":"21702","city":"FORT DETRICK","state":"MD","country":"USA"},"organization_type":"OFFICE"},"status":{"active":false,"archive_date":"2024-09-15","archive_type":"auto_custom"},"contacts":[{"name":"Brenda Mena","role":"primary","email":"brenda.i.mena.civ@health.mil"}],"base_type":{"code":"r","label":"Sources Sought"},"notice_id":"83eb70a6959c421b8ab867c01e4e4bba","provenance":{"extract":{"url":"https://s3.amazonaws.com/falextracts/Contract%20Opportunities/Archived%20Data/FY2024_archived_opportunities.csv","etag":"\"d582488fe153a9f11bf629913d176ffc-137\"","fetched_at":"2026-09-16T19:07:39.720164Z","row_sha256":"ac46739a6dec3ebc59155a36bb669e0cb1100ab4b66efccd2ba8024d3670d093","last_modified":"2026-09-13T14:47:40Z"},"updated_at":"2026-09-16T19:07:39.720164Z","first_seen_at":"2026-09-16T19:07:39.720164Z"},"description":{"text":"Synopses – Notice of Intent to Award Sole Source to Date: 22 July 2024 Year: FY2024 Contracting Office Zip Code: 21702-9232 Contracting Office Address – USA Medical Research Acquisition Activity, 820 Chandler Street, Fort Detrick, MD 21702-5014 Subject: Notice of Intent to Sole Source Award Shank 2 Cryorecovery Support for the Medical Readiness Systems Biology Branch (MRSB) for the Walter Reed Army Institute of Research (WRAIR) The United State Army Medical Research Acquisition activity intends to negotiate on a sole source basis, IWA FAR 6.302-1(b)(1)(i), with Jackson Laboratory located at 600 Main Street, Bar Harbor, Maine 04609.. The Medical Readiness Systems Biology Branch (MRSB) at the Walter Reed Army Institute of Research (WRAIR) conducts research in military psychiatry and neuroscience, as well as a continuum of research from basic science to applied field studies. The purpose of this requirement is to have a specialized laboratory to perform Cryorecovery, custom breeding and cryopreservation on a specific genetic mouse line. This will keep consistency with research studies. Objectives: The vendor’s services will support MRSB objectives, by taking the cryopreserved sperm line provided by MRSB and reviving the mouse line from a compatible and specific transgenic C57BL/6J (Stock 000664) female cohort (solely owned by the vendor). The vendor will then be providing MRSB with mice of the specific genetic line with the specified engineered mutation(s), existing transgene(s), and strain background as specifically requested. The laboratory cryorecovery, custom breeding, and cryopreservation will be conducted off-site, at the vendor’s laboratory. Minimum Essential Characteristics (MECs) include: Vendor will develop a mouse colony from cryopreserved sperm from 2 male Shank2 homozygous Nestin-Cre hemizygous mice provided by WRAIR. Supply WRAIR with the first shipment of 10 male Shank2 homozygous Nestin-Cre hemizygous mice at 6-8 weeks of age. After a minimum of two months after delivering shipment one, supply WRAIR with a second shipment of 30 male Shank2 homozygous Nestin-Cre hemizygous mice at 6-8 weeks of age. Provide a protocol about how to inject tamoxifen (dose etc.) to mice for inducible-CRE activation. Deliver the protocol to test the success of gene editing, e.g. PCR protocol, primer, and kit information. Provide a protocol outlining the methodology necessary for developing and maintaining a mouse colony. Isolated and ship cryopreserved sperm from 2 male Shank2 homozygous Nestin-Cre hemizygous mice to WRAIR for prolonged cryopreservation. THIS NOTICE OF INTENT IS NOT A REQUEST FOR COMPETITIVE QUOTATIONS. Responsible, interested parties may identify their interest by submitting capability information, in writing, by 2:00 p.m. EST, Friday 2 August 2024 to Ms. Brenda Mena at brenda.i.mena.civ@health.mil . Supporting evidence must be furnished in sufficient detail to demonstrate the firm’s ability to provide the stated capability. Responses will be evaluated; however, a determination by the Government not to compete the proposed procurement based upon responses to this notice is solely within the discretion of the Government. If no responses are received, USAMRAA will proceed with the sole source contract.","origin":"extract"},"notice_type":{"code":"s","label":"Special Notice"},"schema_version":1,"solicitation_number":"PANMRA24P0000-004380","place_of_performance":{"zip":"20910","city":{"name":"Silver Spring"},"state":{"code":"MD"},"country":{"code":"USA"}},"product_service_code":"AN12"}],"due_at":"2024-06-14T14:00:00Z","due_date":"2024-06-14","closes_at":"2024-06-14T14:00:00Z","awardable":false,"dept_key":"d-097","dept_name":"DEPT OF DEFENSE","sub_key":"s-97DH","sub_name":"DEFENSE HEALTH AGENCY (DHA)","office_key":"o-HT9425","office_name":"ARMY MED RES ACQ ACTIVITY","state":"MD","county":"24031","county_name":"Montgomery County","city":"2472450","city_name":"Silver Spring","country":"USA","winner_key":null,"amount":null,"linked_awards":0,"cancelled":false,"archived":false,"updated_at":"2026-09-16T21:18:12.857524Z","principal_notice_id":"83eb70a6959c421b8ab867c01e4e4bba","description":{"text":"Synopses – Notice of Intent to Award Sole Source to Date: 22 July 2024 Year: FY2024 Contracting Office Zip Code: 21702-9232 Contracting Office Address – USA Medical Research Acquisition Activity, 820 Chandler Street, Fort Detrick, MD 21702-5014 Subject: Notice of Intent to Sole Source Award Shank 2 Cryorecovery Support for the Medical Readiness Systems Biology Branch (MRSB) for the Walter Reed Army Institute of Research (WRAIR) The United State Army Medical Research Acquisition activity intends to negotiate on a sole source basis, IWA FAR 6.302-1(b)(1)(i), with Jackson Laboratory located at 600 Main Street, Bar Harbor, Maine 04609.. The Medical Readiness Systems Biology Branch (MRSB) at the Walter Reed Army Institute of Research (WRAIR) conducts research in military psychiatry and neuroscience, as well as a continuum of research from basic science to applied field studies. The purpose of this requirement is to have a specialized laboratory to perform Cryorecovery, custom breeding and cryopreservation on a specific genetic mouse line. This will keep consistency with research studies. Objectives: The vendor’s services will support MRSB objectives, by taking the cryopreserved sperm line provided by MRSB and reviving the mouse line from a compatible and specific transgenic C57BL/6J (Stock 000664) female cohort (solely owned by the vendor). The vendor will then be providing MRSB with mice of the specific genetic line with the specified engineered mutation(s), existing transgene(s), and strain background as specifically requested. The laboratory cryorecovery, custom breeding, and cryopreservation will be conducted off-site, at the vendor’s laboratory. Minimum Essential Characteristics (MECs) include: Vendor will develop a mouse colony from cryopreserved sperm from 2 male Shank2 homozygous Nestin-Cre hemizygous mice provided by WRAIR. Supply WRAIR with the first shipment of 10 male Shank2 homozygous Nestin-Cre hemizygous mice at 6-8 weeks of age. After a minimum of two months after delivering shipment one, supply WRAIR with a second shipment of 30 male Shank2 homozygous Nestin-Cre hemizygous mice at 6-8 weeks of age. Provide a protocol about how to inject tamoxifen (dose etc.) to mice for inducible-CRE activation. Deliver the protocol to test the success of gene editing, e.g. PCR protocol, primer, and kit information. Provide a protocol outlining the methodology necessary for developing and maintaining a mouse colony. Isolated and ship cryopreserved sperm from 2 male Shank2 homozygous Nestin-Cre hemizygous mice to WRAIR for prolonged cryopreservation. THIS NOTICE OF INTENT IS NOT A REQUEST FOR COMPETITIVE QUOTATIONS. Responsible, interested parties may identify their interest by submitting capability information, in writing, by 2:00 p.m. EST, Friday 2 August 2024 to Ms. Brenda Mena at brenda.i.mena.civ@health.mil . Supporting evidence must be furnished in sufficient detail to demonstrate the firm’s ability to provide the stated capability. Responses will be evaluated; however, a determination by the Government not to compete the proposed procurement based upon responses to this notice is solely within the discretion of the Government. If no responses are received, USAMRAA will proceed with the sole source contract.","html":null,"origin":"extract"},"contacts":[{"name":"Brenda Mena","role":"primary","email":"brenda.i.mena.civ@health.mil"}],"place_of_performance":{"zip":"20910","city":{"name":"Silver Spring"},"state":{"code":"MD"},"country":{"code":"USA"}},"office_address":{"zip":"21702","city":"FORT DETRICK","state":"MD","country":"USA"},"naics_codes":["621511"],"award":null,"attachments":[],"awards":[],"related":[{"key":"HT942526RE004","latest_notice_id":"d2b355b9ba3f4796b4639c7664f17bfa","title":"Women, Infant, Children Overseas Contract","solicitation_number":"HT9425-26-R-E004","notice_type":"o","first_type":"o","first_posted":"2026-08-18","last_posted":"2026-08-27","notices":3,"due_at":"2026-09-18T14:00:00Z","due_date":"2026-09-18","closes_at":"2026-09-18T14:00:00Z","awardable":true,"open":true,"dept_key":"d-097","dept_name":"DEPT OF DEFENSE","sub_key":"s-97DH","sub_name":"DEFENSE HEALTH AGENCY (DHA)","office_key":"o-HT9425","office_name":"ARMY MED RES ACQ ACTIVITY","naics":"541611","psc":"R408","set_aside":"8A","state":"VA","county":"51610","county_name":"City of Falls Church","city":"5127200","city_name":"Falls Church","country":"USA","winner":null,"winner_key":null,"amount":null,"linked_awards":0,"cancelled":false,"archived":false,"updated_at":"2026-09-16T21:18:12.857524Z"},{"key":"HT942626QE031","latest_notice_id":"2c4d09774d794c22961a3aaec353e88e","title":"Blanket Purchase Agreement for Medical Gases and Dry Ice","solicitation_number":"HT942626QE031","notice_type":"k","first_type":"k","first_posted":"2026-06-12","last_posted":"2026-08-26","notices":6,"due_at":"2026-10-01T15:00:00Z","due_date":"2026-10-01","closes_at":"2026-10-01T15:00:00Z","awardable":true,"open":true,"dept_key":"d-097","dept_name":"DEPT OF DEFENSE","sub_key":"s-97DH","sub_name":"DEFENSE HEALTH AGENCY (DHA)","office_key":"o-HT9425","office_name":"ARMY MED RES ACQ ACTIVITY","naics":"325120","psc":"6830","set_aside":"SBA","state":"MD","county":"24031","county_name":"Montgomery County","city":"2472450","city_name":"Silver Spring","country":"USA","winner":null,"winner_key":null,"amount":null,"linked_awards":0,"cancelled":false,"archived":false,"updated_at":"2026-09-16T21:18:12.857524Z"},{"key":"HT942726RE015","latest_notice_id":"3f41946e77904b6c9444a053683c4bfa","title":"COMBINED SYNOPSIS/SOLICITATION for Regulated Medical Waste services","solicitation_number":"HT942726RE015","notice_type":"k","first_type":"k","first_posted":"2026-08-27","last_posted":"2026-09-14","notices":3,"due_at":"2026-10-05T18:00:00Z","due_date":"2026-10-05","closes_at":"2026-10-05T18:00:00Z","awardable":true,"open":true,"dept_key":"d-097","dept_name":"DEPT OF DEFENSE","sub_key":"s-97DH","sub_name":"DEFENSE HEALTH AGENCY (DHA)","office_key":"o-HT9425","office_name":"ARMY MED RES ACQ ACTIVITY","naics":"562211","psc":"S222","set_aside":"SBA","state":null,"county":null,"county_name":null,"city":null,"city_name":null,"country":null,"winner":null,"winner_key":null,"amount":null,"linked_awards":0,"cancelled":false,"archived":false,"updated_at":"2026-09-16T21:18:12.857524Z"}]}