This is a Notice of Intent, not a request for proposal. The National Institute of Health, Clinical Center (NIH-CC) intends to negotiate on an other than full and open competition basis with the following vendor: Fisher Scientific.
\n\nAcquisition Description:
\n\nThe NIH Clinical Center, Department of Transfusion Medicine (DTM), Infectious Diseases Section requires acquisition of a 1) Real-Time PCR System, 2) an Automated Nucleic Acid Extractor and 3) a microvolume spectrophotometer to support clinical research and the development, optimization, and validation of diagnostic assays for hepatitis viruses and other transfusion-transmitted pathogens.
\n\nThe required system must support generation of high-quality quantification data from clinical specimens, including viral RNA/DNA and host-derived nucleic acids. The instrument must enable applications such as targeted genome amplification, work with a wider dynamic detection range, support the library prep for viral genome sequencing, and assay development workflows necessary for evaluating test performance and refining diagnostic methods prior to implementation in a clinical testing environment.
\n\nThe system must meet the following functional and operational requirements:
\n\nThe statutory authority for this sole source requirement is 41 U.S.C. 253(c) (1) as implemented by FAR 6.302-1 only one responsible source and no other supply of service will satisfy agency requirements. THIS IS NOT A REQUEST FOR PROPOSAL. All responsible sources that could provide the required may submit a capability statement that will be considered by email (subject line to reference NOI-OLAO-CC-27-000121) by 12:00 PM eastern standard time on 10/23/2026 to: valerie.gregorio@nih.gov.
\n\nAll responses received by the closing date of this synopsis will be considered by the Government. A determination not to compete this requirement, based upon responses to this notice, is solely within the discretion of the Government.
\n\n\n\n","text":"This is a Notice of Intent, not a request for proposal. The National Institute of Health, Clinical Center (NIH-CC) intends to negotiate on an other than full and open competition basis with the following vendor: Fisher Scientific.\n\nAcquisition Description:\n\nThe NIH Clinical Center, Department of Transfusion Medicine (DTM), Infectious Diseases Section requires acquisition of a 1) Real-Time PCR System, 2) an Automated Nucleic Acid Extractor and 3) a microvolume spectrophotometer to support clinical research and the development, optimization, and validation of diagnostic assays for hepatitis viruses and other transfusion-transmitted pathogens.\n\nThe required system must support generation of high-quality quantification data from clinical specimens, including viral RNA/DNA and host-derived nucleic acids. The instrument must enable applications such as targeted genome amplification, work with a wider dynamic detection range, support the library prep for viral genome sequencing, and assay development workflows necessary for evaluating test performance and refining diagnostic methods prior to implementation in a clinical testing environment.\n\nThe system must meet the following functional and operational requirements:\n\n• High data accuracy and reproducibility to ensure reliable detection of viral variants and evaluation of assay performance;\n\n• Low- to moderate-throughput capability appropriate for assay development, pilot studies, and validation activities involving smaller sample sets;\n\n• Rapid turnaround times to support iterative testing and optimization of clinical assays;\n\n• Flexible run configurations that allow efficient processing of varying sample volumes without excess capacity;\n\n• Cost-efficient operation, including the ability to minimize per-run and per-sample costs for pathogen detection;\n\n• Integrated and streamlined workflows, including nucleic acid extraction, amplification, quantification and data analysis within a platform from the same vendor to reduce complexity and variability;\n\n• Ease of use and standardized operation, supporting reproducibility and implementation in a clinical laboratory environment;\n\n• Compatibility with established nucleic acid preparation and amplification methods and existing laboratory workflows.\n\n• The flexibility to be using the systems in a CLIA certified environment.\n\nThe statutory authority for this sole source requirement is 41 U.S.C. 253(c) (1) as implemented by FAR 6.302-1 only one responsible source and no other supply of service will satisfy agency requirements. THIS IS NOT A REQUEST FOR PROPOSAL. All responsible sources that could provide the required may submit a capability statement that will be considered by email (subject line to reference NOI-OLAO-CC-27-000121) by 12:00 PM eastern standard time on 10/23/2026 to: valerie.gregorio@nih.gov.\n\nAll responses received by the closing date of this synopsis will be considered by the Government. A determination not to compete this requirement, based upon responses to this notice, is solely within the discretion of the Government.","origin":"detail"},"notice_type":{"code":"s","label":"Special Notice"},"schema_version":1,"solicitation_number":"NOI-OLAO-CC-27-000121","place_of_performance":{"zip":"20892","city":{"code":"7125","name":"Bethesda"},"state":{"code":"MD","name":"Maryland"},"country":{"code":"USA","name":"UNITED STATES"}},"product_service_code":"6640"},{"dates":{"posted":"2026-10-08","posted_at":"2026-10-08T14:03:30.272Z","created_at":"2026-10-08T14:03:16.392Z","modified_at":"2026-10-08T14:03:30.278Z","response_deadline":{"raw":"2026-10-23T12:00:00-04:00","utc":"2026-10-23T16:00:00Z","date":"2026-10-23","time":"12:00:00","timezone":"America/New_York","utc_offset_seconds":-14400}},"links":{"sam":"https://sam.gov/workspace/contract/opp/bf6b20798a274eb2936262d401e097a7/view"},"naics":{"codes":["334516"],"primary":"334516"},"title":"Intent to Sole Source - Medical/Scientific Instruments for the Department of Transfusion Medicine, NIH Clinical Center","agency":{"office":{"name":"NATIONAL INSTITUTES OF HEALTH"},"subtier":{"code":"7529","name":"NATIONAL INSTITUTES OF HEALTH"},"department":{"code":"075","name":"HEALTH AND HUMAN SERVICES, DEPARTMENT OF"},"office_address":{"zip":"20892","city":"Bethesda","state":"MD","country":"US"},"organization_id":"100019747","organization_type":"AGENCY"},"status":{"active":true,"latest":true,"deleted":false,"archived":false,"cancelled":false,"publication":"published","archive_date":"2026-11-07","archive_type":"auto15"},"history":[{"index":2,"title":"Intent to Sole Source - Medical/Scientific Instruments for the Department of Transfusion Medicine, NIH Clinical Center","action":"publish","latest":true,"deleted":false,"archived":false,"cancelled":false,"posted_at":"2026-10-08T14:03:30.272Z","notice_type":{"code":"s","label":"Special Notice"},"request_type":"modify","opportunity_id":"bf6b20798a274eb2936262d401e097a7","solicitation_number":"NOI-OLAO-CC-27-000121","parent_opportunity_id":"b95b5fc579dd4e7fa6b27d283a9049ff"},{"index":1,"title":"Intent to Sole Source - Medical/Scientific Instruments for the Department of Transfusion Medicine, NIH Clinical Center","action":"publish","latest":false,"deleted":false,"archived":false,"cancelled":false,"posted_at":"2026-10-08T14:02:57.050Z","notice_type":{"code":"s","label":"Special Notice"},"request_type":"submit","opportunity_id":"b95b5fc579dd4e7fa6b27d283a9049ff","solicitation_number":"NOI-OLAO-CC-27-000121"}],"base_type":{"code":"s","label":"Special Notice"},"notice_id":"bf6b20798a274eb2936262d401e097a7","lineage_id":"b95b5fc579dd4e7fa6b27d283a9049ff","provenance":{"detail":{"endpoints":["opportunity","resources","history"],"fetched_at":"2026-10-10T00:59:54.316963261Z"},"extract":{"url":"https://s3.amazonaws.com/falextracts/Contract%20Opportunities/datagov/ContractOpportunitiesFullCSV.csv","etag":"\"88a39a008f4c126e532dc85ce516a626-26\"","fetched_at":"2026-10-09T04:25:46.346911714Z","row_sha256":"a44586528f01e04006def74bd5645d17661baff36781725fed19cc15f0f2c0c1","last_modified":"2026-10-09T03:30:27Z"},"updated_at":"2026-10-10T00:59:54.316963261Z","first_seen_at":"2026-10-09T04:25:46.346911714Z"},"description":{"html":"This is a Notice of Intent, not a request for proposal. The National Institute of Health, Clinical Center (NIH-CC) intends to negotiate on an other than full and open competition basis with the following vendor: Fisher Scientific.
\n\nAcquisition Description:
\n\nThe NIH Clinical Center, Department of Transfusion Medicine (DTM), Infectious Diseases Section requires acquisition of a 1) Real-Time PCR System, 2) an Automated Nucleic Acid Extractor and 3) a microvolume spectrophotometer to support clinical research and the development, optimization, and validation of diagnostic assays for hepatitis viruses and other transfusion-transmitted pathogens.
\n\nThe required system must support generation of high-quality quantification data from clinical specimens, including viral RNA/DNA and host-derived nucleic acids. The instrument must enable applications such as targeted genome amplification, work with a wider dynamic detection range, support the library prep for viral genome sequencing, and assay development workflows necessary for evaluating test performance and refining diagnostic methods prior to implementation in a clinical testing environment.
\n\nThe system must meet the following functional and operational requirements:
\n\nThe statutory authority for this sole source requirement is 41 U.S.C. 253(c) (1) as implemented by FAR 6.302-1 only one responsible source and no other supply of service will satisfy agency requirements. THIS IS NOT A REQUEST FOR PROPOSAL. All responsible sources that could provide the required may submit a capability statement that will be considered by email (subject line to reference NOI-OLAO-CC-27-000121) by 12:00 PM eastern standard time on 10/23/2026 to: valerie.gregorio@nih.gov.
\n\nAll responses received by the closing date of this synopsis will be considered by the Government. A determination not to compete this requirement, based upon responses to this notice, is solely within the discretion of the Government.
\n\n\n\n","text":"This is a Notice of Intent, not a request for proposal. The National Institute of Health, Clinical Center (NIH-CC) intends to negotiate on an other than full and open competition basis with the following vendor: Fisher Scientific.\n\nAcquisition Description:\n\nThe NIH Clinical Center, Department of Transfusion Medicine (DTM), Infectious Diseases Section requires acquisition of a 1) Real-Time PCR System, 2) an Automated Nucleic Acid Extractor and 3) a microvolume spectrophotometer to support clinical research and the development, optimization, and validation of diagnostic assays for hepatitis viruses and other transfusion-transmitted pathogens.\n\nThe required system must support generation of high-quality quantification data from clinical specimens, including viral RNA/DNA and host-derived nucleic acids. The instrument must enable applications such as targeted genome amplification, work with a wider dynamic detection range, support the library prep for viral genome sequencing, and assay development workflows necessary for evaluating test performance and refining diagnostic methods prior to implementation in a clinical testing environment.\n\nThe system must meet the following functional and operational requirements:\n\n• High data accuracy and reproducibility to ensure reliable detection of viral variants and evaluation of assay performance;\n\n• Low- to moderate-throughput capability appropriate for assay development, pilot studies, and validation activities involving smaller sample sets;\n\n• Rapid turnaround times to support iterative testing and optimization of clinical assays;\n\n• Flexible run configurations that allow efficient processing of varying sample volumes without excess capacity;\n\n• Cost-efficient operation, including the ability to minimize per-run and per-sample costs for pathogen detection;\n\n• Integrated and streamlined workflows, including nucleic acid extraction, amplification, quantification and data analysis within a platform from the same vendor to reduce complexity and variability;\n\n• Ease of use and standardized operation, supporting reproducibility and implementation in a clinical laboratory environment;\n\n• Compatibility with established nucleic acid preparation and amplification methods and existing laboratory workflows.\n\n• The flexibility to be using the systems in a CLIA certified environment.\n\nThe statutory authority for this sole source requirement is 41 U.S.C. 253(c) (1) as implemented by FAR 6.302-1 only one responsible source and no other supply of service will satisfy agency requirements. THIS IS NOT A REQUEST FOR PROPOSAL. All responsible sources that could provide the required may submit a capability statement that will be considered by email (subject line to reference NOI-OLAO-CC-27-000121) by 12:00 PM eastern standard time on 10/23/2026 to: valerie.gregorio@nih.gov.\n\nAll responses received by the closing date of this synopsis will be considered by the Government. A determination not to compete this requirement, based upon responses to this notice, is solely within the discretion of the Government.","origin":"detail"},"notice_type":{"code":"s","label":"Special Notice"},"schema_version":1,"solicitation_number":"NOI-OLAO-CC-27-000121","place_of_performance":{"zip":"20892","city":{"code":"7125","name":"Bethesda"},"state":{"code":"MD","name":"Maryland"},"country":{"code":"USA","name":"UNITED STATES"}},"product_service_code":"6640"}],"due_at":"2026-10-23T16:00:00Z","due_date":"2026-10-23","closes_at":"2026-10-23T16:00:00Z","awardable":false,"dept_key":"d-075","dept_name":"HEALTH AND HUMAN SERVICES, DEPARTMENT OF","sub_key":"s-7529","sub_name":"NATIONAL INSTITUTES OF HEALTH","office_key":"o-n-NATIONALINSTITUTESOFHEALTH","office_name":"NATIONAL INSTITUTES OF HEALTH","state":"MD","county":"24031","county_name":"Montgomery County","city":"2407125","city_name":"Bethesda","country":"USA","state_source":null,"state_evidence":null,"site_key":null,"winner_key":null,"amount":null,"linked_awards":0,"cancelled":false,"archived":false,"updated_at":"2026-10-09T04:30:03.659222Z","principal_notice_id":"bf6b20798a274eb2936262d401e097a7","description":{"text":"This is a Notice of Intent, not a request for proposal. The National Institute of Health, Clinical Center (NIH-CC) intends to negotiate on an other than full and open competition basis with the following vendor: Fisher Scientific.\n\nAcquisition Description:\n\nThe NIH Clinical Center, Department of Transfusion Medicine (DTM), Infectious Diseases Section requires acquisition of a 1) Real-Time PCR System, 2) an Automated Nucleic Acid Extractor and 3) a microvolume spectrophotometer to support clinical research and the development, optimization, and validation of diagnostic assays for hepatitis viruses and other transfusion-transmitted pathogens.\n\nThe required system must support generation of high-quality quantification data from clinical specimens, including viral RNA/DNA and host-derived nucleic acids. The instrument must enable applications such as targeted genome amplification, work with a wider dynamic detection range, support the library prep for viral genome sequencing, and assay development workflows necessary for evaluating test performance and refining diagnostic methods prior to implementation in a clinical testing environment.\n\nThe system must meet the following functional and operational requirements:\n\n• High data accuracy and reproducibility to ensure reliable detection of viral variants and evaluation of assay performance;\n\n• Low- to moderate-throughput capability appropriate for assay development, pilot studies, and validation activities involving smaller sample sets;\n\n• Rapid turnaround times to support iterative testing and optimization of clinical assays;\n\n• Flexible run configurations that allow efficient processing of varying sample volumes without excess capacity;\n\n• Cost-efficient operation, including the ability to minimize per-run and per-sample costs for pathogen detection;\n\n• Integrated and streamlined workflows, including nucleic acid extraction, amplification, quantification and data analysis within a platform from the same vendor to reduce complexity and variability;\n\n• Ease of use and standardized operation, supporting reproducibility and implementation in a clinical laboratory environment;\n\n• Compatibility with established nucleic acid preparation and amplification methods and existing laboratory workflows.\n\n• The flexibility to be using the systems in a CLIA certified environment.\n\nThe statutory authority for this sole source requirement is 41 U.S.C. 253(c) (1) as implemented by FAR 6.302-1 only one responsible source and no other supply of service will satisfy agency requirements. THIS IS NOT A REQUEST FOR PROPOSAL. All responsible sources that could provide the required may submit a capability statement that will be considered by email (subject line to reference NOI-OLAO-CC-27-000121) by 12:00 PM eastern standard time on 10/23/2026 to: valerie.gregorio@nih.gov.\n\nAll responses received by the closing date of this synopsis will be considered by the Government. A determination not to compete this requirement, based upon responses to this notice, is solely within the discretion of the Government.","html":"This is a Notice of Intent, not a request for proposal. The National Institute of Health, Clinical Center (NIH-CC) intends to negotiate on an other than full and open competition basis with the following vendor: Fisher Scientific.
\n\nAcquisition Description:
\n\nThe NIH Clinical Center, Department of Transfusion Medicine (DTM), Infectious Diseases Section requires acquisition of a 1) Real-Time PCR System, 2) an Automated Nucleic Acid Extractor and 3) a microvolume spectrophotometer to support clinical research and the development, optimization, and validation of diagnostic assays for hepatitis viruses and other transfusion-transmitted pathogens.
\n\nThe required system must support generation of high-quality quantification data from clinical specimens, including viral RNA/DNA and host-derived nucleic acids. The instrument must enable applications such as targeted genome amplification, work with a wider dynamic detection range, support the library prep for viral genome sequencing, and assay development workflows necessary for evaluating test performance and refining diagnostic methods prior to implementation in a clinical testing environment.
\n\nThe system must meet the following functional and operational requirements:
\n\nThe statutory authority for this sole source requirement is 41 U.S.C. 253(c) (1) as implemented by FAR 6.302-1 only one responsible source and no other supply of service will satisfy agency requirements. THIS IS NOT A REQUEST FOR PROPOSAL. All responsible sources that could provide the required may submit a capability statement that will be considered by email (subject line to reference NOI-OLAO-CC-27-000121) by 12:00 PM eastern standard time on 10/23/2026 to: valerie.gregorio@nih.gov.
\n\nAll responses received by the closing date of this synopsis will be considered by the Government. A determination not to compete this requirement, based upon responses to this notice, is solely within the discretion of the Government.
\n\n\n\n","origin":"detail"},"contacts":null,"place_of_performance":{"zip":"20892","city":{"code":"7125","name":"Bethesda"},"state":{"code":"MD","name":"Maryland"},"country":{"code":"USA","name":"UNITED STATES"}},"office_address":{"zip":"20892","city":"Bethesda","state":"MD","country":"US"},"naics_codes":["334516"],"award":null,"attachments":[{"resource_id":"231aaae4b1de4214af471110e5f3fcac","name":"2-SOW_ThermoFisher_07202026.docx","kind":"file","mime_type":".docx","size_bytes":39394,"posted_at":"2026-10-08T14:02:57.050Z","export_controlled":false,"sha256":null,"url":"https://sam.gov/api/prod/opps/v3/opportunities/resources/files/231aaae4b1de4214af471110e5f3fcac/download","mirrored":false}],"awards":[],"related":[],"similar_open":[{"key":"NISTMMLFY27SS01","latest_notice_id":"850a8fc718dc434d89f77ecfcb0c4251","title":"Graphite Furnace Atomic Absorption Spectrometer","solicitation_number":"NIST-MML-FY27-SS01","notice_type":"r","first_type":"r","first_posted":"2026-10-28","last_posted":"2026-10-28","notices":1,"due_at":"2026-11-28T19:00:00Z","due_date":"2026-11-28","closes_at":"2026-11-28T19:00:00Z","awardable":true,"open":true,"removed":false,"dept_key":"d-013","dept_name":"COMMERCE, DEPARTMENT OF","sub_key":"s-1341","sub_name":"NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY","office_key":"o-1333ND","office_name":"DEPT OF COMMERCE NIST","naics":"334516","psc":"6640","set_aside":null,"state":"MD","county":"24031","county_name":"Montgomery County","city":"2431175","city_name":"Gaithersburg","country":"USA","place_scope":"nationwide","state_source":null,"state_evidence":null,"site":null,"site_key":null,"winner":null,"winner_key":null,"amount":null,"linked_awards":0,"cancelled":false,"archived":false,"removed_at":null,"updated_at":"2026-10-29T04:15:54.363094Z"},{"key":"NISTSS26CHIPS13","latest_notice_id":"0124b2bd52b742b8a14350289fc0626d","title":"Sources Sought Notice for Mid-IR Optical Frequency Comb","solicitation_number":"NIST-SS26-CHIPS-13","notice_type":"r","first_type":"r","first_posted":"2025-11-19","last_posted":"2025-11-19","notices":1,"due_at":"2026-12-03T22:00:00Z","due_date":"2026-12-03","closes_at":"2026-12-03T22:00:00Z","awardable":true,"open":true,"removed":false,"dept_key":"d-013","dept_name":"COMMERCE, DEPARTMENT OF","sub_key":"s-1341","sub_name":"NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY","office_key":"o-1333ND","office_name":"DEPT OF COMMERCE NIST","naics":"334516","psc":"6640","set_aside":null,"state":"MD","county":"24031","county_name":"Montgomery County","city":"2431175","city_name":"Gaithersburg","country":"USA","place_scope":"nationwide","state_source":null,"state_evidence":null,"site":null,"site_key":null,"winner":null,"winner_key":null,"amount":null,"linked_awards":0,"cancelled":false,"archived":false,"removed_at":null,"updated_at":"2026-09-24T03:25:58.922164Z"},{"key":"NISTSS26CHIPS16","latest_notice_id":"f06db812fc2549fc995d22d26b2dbc5c","title":"Sources Sought Notice for Continuous Wave Parametric Oscillator (CW OPO) Laser System","solicitation_number":"NIST-SS26-CHIPS-16","notice_type":"r","first_type":"r","first_posted":"2025-11-20","last_posted":"2025-11-20","notices":1,"due_at":"2026-12-05T16:00:00Z","due_date":"2026-12-05","closes_at":"2026-12-05T16:00:00Z","awardable":true,"open":true,"removed":false,"dept_key":"d-013","dept_name":"COMMERCE, DEPARTMENT OF","sub_key":"s-1341","sub_name":"NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY","office_key":"o-1333ND","office_name":"DEPT OF COMMERCE NIST","naics":"334516","psc":"6640","set_aside":null,"state":"MD","county":"24031","county_name":"Montgomery County","city":"2431175","city_name":"Gaithersburg","country":"USA","place_scope":"nationwide","state_source":null,"state_evidence":null,"site":null,"site_key":null,"winner":null,"winner_key":null,"amount":null,"linked_awards":0,"cancelled":false,"archived":false,"removed_at":null,"updated_at":"2026-09-24T03:25:58.922164Z"}],"similar_open_total":39}