# MSD TOTAL SERVICE PACKAGE SILVER FOR CCD CAMERA Canonical: https://abierto.us/opportunities/noiniaid252257361 - Solicitation number: NOI-NIAID-25-2257361 - Notice type: Combined synopsis and solicitation - Status: Closed. Deadline was May 1, 2025 at 12:00 PM EDT - Department: Department of Health and Human Services - Agency: National Institutes of Health - Contracting office: National Institutes of Health Niaid (75N930) - NAICS: 811210 Electronic and Precision Equipment Repair and Maintenance - Product or service code: J066 Maintenance, Repair and Rebuilding of Equipment: Instruments and Laboratory Equipment - Place of performance: Bethesda, Maryland - County: Montgomery County (FIPS 24031). https://abierto.us/counties/montgomery-county-md-24031 - City: Bethesda. https://abierto.us/cities/bethesda-md-2407125 - First posted: April 21, 2025 - Last posted: April 21, 2025 - SAM.gov: https://sam.gov/workspace/contract/opp/98ef428cceec4fa9a5fe29e701911de7/view ## Description This is a Notice of Intent, not a request for proposal. The National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health (NIH) intends to negotiate an other than full and open competition basis with Meso Scale Diagnostics for a Total Service Package Silver for CCD Camera. The B Cell Immunology Section aids the Vaccine Research Center (VRC) by supporting the development of monoclonal antibodies and vaccines for infectious diseases such as HIV, Influenza, Ebola, and more recently SARS-CoV-2 Coronavirus. Support is through the state-of-the-art laboratory performing Phase 1 and Phase 3 clinical end point testing to inform further study designs, research questions and vaccine modification and design. As part of a broader strategy to accelerate the development of monoclonal antibodies as therapy for targeting SARS CoV-2 spike and its newly emerging variants, VIP has identified the electrochemiluminescent (ECL) assay format as the most reliable and sensitive assay system that offers high dynamic range in the detection of antibodies isolated specific to SARS-CoV-2 spike (S2P). Specifically, the VIP is in the process of developing an assay for detection of binding antibodies to subdomains of the spike such as RBD, NTD, S1 and S2, which offers high throughput measurement of immune responses elicited by infections. As the threat of COVID-19 continues in the international community with new variants emerging every week, the need for a safe and efficacious monoclonal antibody therapy at an accelerated timeline is a health care priority. To assist in this effort, the VRC-VIP will use the electrochemiluminescent (ECL) assay format which they have recently developed for a SARS CoV-2 specific assay for the detection of specific antibodies directed towards SARS CoV-2 S-2P and RBD (or other stabilized version of this same protein), variants and subvariants (B.1.1.529, B.1.351, B.1.617). Spike proteins are 'printed' or 'spotted' in a single well of a MSD 96- well microtiter plate. The VRC-VIP identified the ECL assay as the most reliable and sensitive assay system over the last 10 years, that offers high dynamic range in the detection of specific serum antibodies generate towards a variety of viral proteins. The platform offers extremely high throughput for the simultaneous measurement of antibodies to their epitopes. Capabilities statements must address the capability of providing a priority response equal to a direct contract/service agreement with the manufacturer. The statutory authority for this sole source requirement is 41 U.S.C. 1901 (a) (1) as implemented by FAR 13.106-1 only one responsible source and no other supply of service will satisfy agency requirements. THIS IS NOT A REQUEST FOR PROPOSAL. All responsible sources that could provide comparable services may submit a capabilities statement that will be considered. The documents must be submitted via the NIAID electronic Simplified Acquisition Submission System (eSASS) website at https://esass.nih.gov, (subject line to reference NOI-NIAID-25-2257361 by May 1, 2025, by 12:00 pm eastern standard time. All vendors must register in the eSASS system to submit a capabilities statement. Instructions on how to register / submit quotes are included on the website. Late submissions shall be treated in accordance with the solicitation provision at FAR 52.212-1(f). All responsible sources may submit a capabilities statement that will be considered by this Agency. ## Publications - April 21, 2025: Combined synopsis and solicitation, due May 1, 2025 at 12:00 PM EDT. Notice 98ef428cceec4fa9a5fe29e701911de7. https://sam.gov/workspace/contract/opp/98ef428cceec4fa9a5fe29e701911de7/view ## Points of contact - Maliaka Pinkney, maliaka.pinkney@nih.gov, 2406695308 - Jesse Weidow, weidowjd@niaid.nih.gov, 4063759783 --- Source: SAM.gov Contract Opportunities bulk extract. Confirm deadlines on SAM.gov before responding. Cite https://abierto.us/opportunities/noiniaid252257361.