# HT942525P0045 Notice of Intent to Sole Source

Canonical: https://abierto.us/opportunities/ht942525r0028

- Solicitation number: HT942525P0045
- Notice type: Special notice
- Status: Awarded to Aptagen LLC for $582,660.00
- Department: Department of Defense
- Agency: Defense Health Agency (Dha)
- Contracting office: Defense Health Agency (Dha) (n-DEFENSEHEALTHAGENCYDHA)
- NAICS: 325413 In-Vitro Diagnostic Substance Manufacturing
- Product or service code: AN22 Health R&D Services; Health Research And Training; Applied Research
- Place of performance: Frederick, Maryland
- County: Frederick County (FIPS 24021). https://abierto.us/counties/frederick-county-md-24021
- City: Frederick. https://abierto.us/cities/frederick-md-2430325
- First posted: January 23, 2025
- Last posted: December 17, 2025
- SAM.gov: https://sam.gov/workspace/contract/opp/7372a4d602a8425ea92dc76d5f92cb24/view

## Description

The Defense Health Agency Contracting Activity (DHACA) intends to modify the existing contract for an increase in service on a sole source basis In Accordance With (IAW) Federal Acquisition Regulation (FAR) part 6 to Aptagen, LLC located at 250 N Main Street, Jacobus, PA 17407 as the only responsible source that can provide the United States Army Medical Research Institute of Infectious Diseases (USAMRIID) for services.

The Performance Work Statement has not changed other than to adjust the number of DNA aptamer generations being provided and adding an additional target of pseudoviruses. USAMRIID has a need to generate no less than one (1) but not to exceed four (4) DNA Aptamer Library Generation per year. These aptamer libraries will consist of ~1000 - ~10,000 targeted aptamers.

These libraries target specific pseudoviruses and/or alpha-conotoxins and/or palytoxins and should be capable of broad-spectrum interactions and libraries targeting four (4) to six (6) viral targets. This is a requirement that was originally identified to support USAMRIID’s project CB11484, Development of broad-spectrum DNA aptamers to neutralize toxins.

The requirement is crucial as it enables USAMRIID’s researchers to ultimately generate one (1) or more DNA aptamers capable of effectively binding and neutralizing specific toxins and viruses. This is an embryonic methodology with promising outlook for future use in the research field as this and similar strategies have not been employed at the institute previously. The services will performed in Frederick , Maryland 21702.

## Award on USAspending

- Recipient: Aptagen LLC (UEI HEK9BF17MKL3)
- Contract: HT942525P0045, purchase order
- Obligated: $194,220.00
- Competition: Not Competed Under SAP, 1 offers received
- Link: award number HT942525P0045 equals the contract number; same awarding office HT9425 (high confidence)
- Record: https://www.usaspending.gov/award/CONT_AWD_HT942525P0045_9700_-NONE-_-NONE-/


## Publications

- January 23, 2025: Special notice, due February 6, 2025 at 1:00 PM EST. Notice 93af703349d24ab4b39a9ea08f6a7311. https://sam.gov/workspace/contract/opp/93af703349d24ab4b39a9ea08f6a7311/view
- March 26, 2025: Award notice. Notice 1e3d04c442944d2491d618e89c730d9f. https://sam.gov/workspace/contract/opp/1e3d04c442944d2491d618e89c730d9f/view
- March 26, 2025: Justification. Notice b9269c59c9e3443fad8b9e81341721eb. https://sam.gov/workspace/contract/opp/b9269c59c9e3443fad8b9e81341721eb/view
- December 17, 2025: Special notice, due January 6, 2026 at 1:00 PM EST. Notice 7372a4d602a8425ea92dc76d5f92cb24. https://sam.gov/workspace/contract/opp/7372a4d602a8425ea92dc76d5f92cb24/view

## Points of contact

- Christina Lewis, christina.m.lewis14.civ@health.mil
- Jayme Fletcher, jayme.l.fletcher2.civ@health.mil

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Source: SAM.gov Contract Opportunities bulk extract and USAspending.gov award data. Confirm deadlines on SAM.gov before responding. Cite https://abierto.us/opportunities/ht942525r0028.