{"canonical":"https://abierto.us/opportunities/ht942525r0028","key":"HT942525R0028","url":"https://abierto.us/opportunities/ht942525r0028","title":"HT942525P0045 Notice of Intent to Sole Source","solicitation_number":"HT942525P0045","notice_type":"s","open":false,"response_deadline":"2026-01-06T18:00:00Z","first_posted":"2025-01-23","last_posted":"2025-12-17","department":"DEPT OF DEFENSE","subagency":"DEFENSE HEALTH AGENCY (DHA)","office":"DEFENSE HEALTH AGENCY (DHA)","naics":"325413","psc":"AN22","set_aside":null,"place_state":"MD","place_county":"24021","place_county_name":"Frederick County","place_city":"2430325","place_city_name":"Frederick","winner":"APTAGEN LLC","award_amount":"582660.00","publications":[{"notice_id":"93af703349d24ab4b39a9ea08f6a7311","title":"Notice of Intent to Sole Source - Aptamer Library Generation Services for USAMRIID","solicitation_number":"HT942525R0028","notice_type":"s","base_type":"s","posted":"2025-01-23","posted_at":null,"due_at":"2025-02-06T18:00:00Z","due_date":"2025-02-06","cancelled":null,"archived":null,"archive_date":"2025-03-06","award_number":null,"awardee_name":null,"amount":null,"link_sam":"https://sam.gov/workspace/contract/opp/93af703349d24ab4b39a9ea08f6a7311/view","enriched":false,"history":[]},{"notice_id":"1e3d04c442944d2491d618e89c730d9f","title":"Aptamer Library Generation Services for USAMRIID","solicitation_number":"HT942525P0045","notice_type":"a","base_type":"s","posted":"2025-03-26","posted_at":null,"due_at":null,"due_date":null,"cancelled":null,"archived":null,"archive_date":"2025-04-09","award_number":"HT942525P0045","awardee_name":"APTAGEN LLC Jacobus","amount":"582660.00","link_sam":"https://sam.gov/workspace/contract/opp/1e3d04c442944d2491d618e89c730d9f/view","enriched":false,"history":[]},{"notice_id":"b9269c59c9e3443fad8b9e81341721eb","title":"Aptamer Library Generation Services for USAMRIID","solicitation_number":"HT942525P0045Justification","notice_type":"u","base_type":"a","posted":"2025-03-26","posted_at":null,"due_at":null,"due_date":null,"cancelled":null,"archived":null,"archive_date":"2025-04-25","award_number":"HT942525P0045","awardee_name":null,"amount":null,"link_sam":"https://sam.gov/workspace/contract/opp/b9269c59c9e3443fad8b9e81341721eb/view","enriched":false,"history":[]},{"notice_id":"7372a4d602a8425ea92dc76d5f92cb24","title":"HT942525P0045 Notice of Intent to Sole Source","solicitation_number":"HT942525P0045","notice_type":"s","base_type":"s","posted":"2025-12-17","posted_at":null,"due_at":"2026-01-06T18:00:00Z","due_date":"2026-01-06","cancelled":null,"archived":null,"archive_date":"2026-01-21","award_number":null,"awardee_name":null,"amount":null,"link_sam":"https://sam.gov/workspace/contract/opp/7372a4d602a8425ea92dc76d5f92cb24/view","enriched":false,"history":[]}],"latest_notice_id":"7372a4d602a8425ea92dc76d5f92cb24","first_type":"s","notices":[{"dates":{"posted":"2025-01-23","response_deadline":{"raw":"2025-02-06T13:00:00-05:00","utc":"2025-02-06T18:00:00Z","date":"2025-02-06","time":"13:00:00","utc_offset_seconds":-18000}},"links":{"sam":"https://sam.gov/workspace/contract/opp/93af703349d24ab4b39a9ea08f6a7311/view"},"naics":{"codes":["325413"],"primary":"325413"},"title":"Notice of Intent to Sole Source - Aptamer Library Generation Services for USAMRIID","agency":{"office":{"code":"HT9425","name":"ARMY MED RES ACQ ACTIVITY"},"subtier":{"code":"97DH","name":"DEFENSE HEALTH AGENCY (DHA)"},"department":{"code":"097","name":"DEPT OF DEFENSE"},"office_address":{"zip":"21702","city":"FORT DETRICK","state":"MD","country":"USA"},"organization_type":"OFFICE"},"status":{"active":false,"archive_date":"2025-03-06","archive_type":"auto_custom"},"contacts":[{"name":"Christina Lewis","role":"primary","email":"christina.m.lewis14.civ@health.mil"},{"name":"Jayme Fletcher","role":"secondary","email":"jayme.l.fletcher2.civ@health.mil"}],"base_type":{"code":"s","label":"Special Notice"},"notice_id":"93af703349d24ab4b39a9ea08f6a7311","provenance":{"extract":{"url":"https://s3.amazonaws.com/falextracts/Contract%20Opportunities/Archived%20Data/FY2025_archived_opportunities.csv","etag":"\"d47226e3d2c6545974b252e103f82b34-139\"","fetched_at":"2026-09-16T17:45:50.850439Z","row_sha256":"ca6d828ec98990fe2bf8e02b440c0b667d2c7214fca780eca93bcd7771338b63","last_modified":"2026-09-13T14:49:20Z"},"updated_at":"2026-09-16T17:45:50.850439Z","first_seen_at":"2026-09-16T17:45:50.850439Z"},"description":{"text":"The U.S. Army Medical Research Acquisition Activity (USAMRAA) intends to award a Firm Fixed Price, sole source, contract on behalf of the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID) to Aptagen, LLC located at 250 N Main Street, Jacobus, PA 17407, under the authority as prescribed in FAR 13.501 (a) (1) ( ii), sole source (including brand name) under the authority of simplified procedures for certain commercial items. This new requirement is for the need to generate two (2) Deoxyribonucleic Acid (DNA) Aptamer Library Generation per anticipated projects per year. These aptamer libraries will consist of ~1000 - ~10,000 targeted aptamers. These libraries will target specific alpha-conotoxins and palytoxins and should be capable of broad-spectrum interactions and libraries targeting four (4) to six (6) viral targets. This new requirement was identified to support USAMRIID’s project NB38075, Development of broad-spectrum DNA aptamers to neutralize toxins. Aptagen LLC is the only vendor capable of providing reagents that can be used on site to initiate the process, train in their use, and then synthesize and characterize the aptamers that are promising candidates. Aptagen, LLC is a leader in aptamer library generation. Aptagen owns its proprietary processes of aptamer development. They are the only company to provide aptamer library kits along with library characterization services. Further, Aptagen LLC provides the ability for USAMRIID to leverage its expertise while retaining possession of the select agent in accordance with USAMRIID’s strict and rigorous access and control protocols, allowing for the production of the libraries within said containment parameters. This notice of intent is NOT a request for quotations (RFQ) and no solicitation document exists for the requirement; however, if a vendor challenges the basis for this requirement, please submit a capability statement that includes sufficient detail and with convincing evidence that clearly demonstrates the capability to provide these services. A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. A request for documentation or additional information or submissions that only ask questions will not be considered as an affirmative response. A determination by the Government not to compete based on responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement or to proceed with a sole source procurement. Capability statements are due no later than 1300 Eastern Time, 06 February 2025. Capability statements shall be submitted, via email ONLY, as a Microsoft Word or Adobe PDF attachment to the following email addresses christina.m.lewis14.civ@health.mil and jayme.l.fletcher2.civ@health.mil. No phone calls will be accepted.","origin":"extract"},"notice_type":{"code":"s","label":"Special Notice"},"schema_version":1,"solicitation_number":"HT942525R0028","place_of_performance":{"zip":"21702","state":{"code":"MD"},"country":{"code":"USA"}},"product_service_code":"AN22"},{"award":{"date":"2025-03-25","amount":"582660.00","number":"HT942525P0045","awardee":{"raw":"APTAGEN LLC Jacobus PA 17407 USA","name":"APTAGEN LLC Jacobus","location":{"zip":"17407","state":{"code":"PA"},"country":{"code":"USA"}}}},"dates":{"posted":"2025-03-26","award_date":"2025-03-25"},"links":{"sam":"https://sam.gov/workspace/contract/opp/1e3d04c442944d2491d618e89c730d9f/view"},"naics":{"codes":["325413"],"primary":"325413"},"title":"Aptamer Library Generation Services for USAMRIID","agency":{"office":{"code":"HT9425","name":"ARMY MED RES ACQ ACTIVITY"},"subtier":{"code":"97DH","name":"DEFENSE HEALTH AGENCY (DHA)"},"department":{"code":"097","name":"DEPT OF DEFENSE"},"office_address":{"zip":"21702","city":"FORT DETRICK","state":"MD","country":"USA"},"organization_type":"OFFICE"},"status":{"active":false,"archive_date":"2025-04-09","archive_type":"auto15"},"contacts":[{"name":"Christina Lewis","role":"primary","email":"christina.m.lewis14.civ@health.mil"},{"name":"Jayme Fletcher","role":"secondary","email":"jayme.l.fletcher2.civ@health.mil"}],"base_type":{"code":"s","label":"Special Notice"},"notice_id":"1e3d04c442944d2491d618e89c730d9f","provenance":{"extract":{"url":"https://s3.amazonaws.com/falextracts/Contract%20Opportunities/Archived%20Data/FY2025_archived_opportunities.csv","etag":"\"d47226e3d2c6545974b252e103f82b34-139\"","fetched_at":"2026-09-16T17:45:50.850439Z","row_sha256":"55f925b29a6fcccdd0ded850c5c1c5ff4293d045cbbea0bc8604062356432d0b","last_modified":"2026-09-13T14:49:20Z"},"updated_at":"2026-09-16T17:45:50.850439Z","first_seen_at":"2026-09-16T17:45:50.850439Z"},"description":{"text":"Aptagen LLC received a firm fixed price contract, as a result of a sole source procurement, for Aptamer Library Generation of two (2) Deoxyribonucleic Acids (DNA) per anticipated projects, per year. The award was issued in accordance with FAR 15.501(a)(1)(ii) -- source (including brand name) under the authority of simplified procedures for certain commercial items, as Aptagen LLC was identified as the only company able to provide aptamer library kits along with library characterization services, while also providing the ability for USAMRIID to leverage its expertise while retaining possession of the select agents in accordance with USAMRIID's strict and rigorous access and control protocols, allowing for the productiopn of the libraries within said containment parameters.","origin":"extract"},"notice_type":{"code":"a","label":"Award Notice"},"schema_version":1,"solicitation_number":"HT942525P0045","place_of_performance":{"zip":"17407","state":{"code":"PA"},"country":{"code":"USA"}},"product_service_code":"AN22"},{"award":{"date":"2025-03-25","number":"HT942525P0045"},"dates":{"posted":"2025-03-26","award_date":"2025-03-25"},"links":{"sam":"https://sam.gov/workspace/contract/opp/b9269c59c9e3443fad8b9e81341721eb/view"},"naics":{"codes":["325413"],"primary":"325413"},"title":"Aptamer Library Generation Services for USAMRIID","agency":{"office":{"code":"HT9425","name":"ARMY MED RES ACQ ACTIVITY"},"subtier":{"code":"97DH","name":"DEFENSE HEALTH AGENCY (DHA)"},"department":{"code":"097","name":"DEPT OF DEFENSE"},"office_address":{"zip":"21702","city":"FORT DETRICK","state":"MD","country":"USA"},"organization_type":"OFFICE"},"status":{"active":false,"archive_date":"2025-04-25","archive_type":"auto30"},"contacts":[{"name":"Christina Lewis","role":"primary","email":"christina.m.lewis14.civ@health.mil"},{"name":"Jayme Fletcher","role":"secondary","email":"jayme.l.fletcher2.civ@health.mil"}],"base_type":{"code":"a","label":"Award Notice"},"notice_id":"b9269c59c9e3443fad8b9e81341721eb","provenance":{"extract":{"url":"https://s3.amazonaws.com/falextracts/Contract%20Opportunities/Archived%20Data/FY2025_archived_opportunities.csv","etag":"\"d47226e3d2c6545974b252e103f82b34-139\"","fetched_at":"2026-09-16T17:45:50.850439Z","row_sha256":"8dce885e8a431a6bd4c817c03778daa7ae678c942f2a1e65b8491c4b95ffdad3","last_modified":"2026-09-13T14:49:20Z"},"updated_at":"2026-09-16T17:45:50.850439Z","first_seen_at":"2026-09-16T17:45:50.850439Z"},"description":{"text":"Sole Source Justification to support award of HT942525P0045 to Aptagen LLC in accordance with FAR 153.501(a)(1)(ii) -- sole source (including brand name) under the authority of simplified procedures for certain commercial items. This requirement is for the generation of two (2) Deoxyribonucleic Acid (DNA) Aptamer Libraries, per anticipated project, per year in support of USAMRIID.","origin":"extract"},"notice_type":{"code":"u","label":"Justification"},"schema_version":1,"solicitation_number":"HT942525P0045Justification","place_of_performance":{"zip":"17407","state":{"code":"PA"},"country":{"code":"USA"}},"product_service_code":"AN22"},{"dates":{"posted":"2025-12-17","response_deadline":{"raw":"2026-01-06T13:00:00-05:00","utc":"2026-01-06T18:00:00Z","date":"2026-01-06","time":"13:00:00","utc_offset_seconds":-18000}},"links":{"sam":"https://sam.gov/workspace/contract/opp/7372a4d602a8425ea92dc76d5f92cb24/view"},"naics":{"codes":["325413"],"primary":"325413"},"title":"HT942525P0045 Notice of Intent to Sole Source","agency":{"office":{"name":"DEFENSE HEALTH AGENCY (DHA)"},"subtier":{"code":"97DH","name":"DEFENSE HEALTH AGENCY (DHA)"},"department":{"code":"097","name":"DEPT OF DEFENSE"},"organization_type":"AGENCY"},"status":{"active":false,"archive_date":"2026-01-21","archive_type":"auto15"},"contacts":[{"name":"Christina Lewis","role":"primary","email":"christina.m.lewis14.civ@health.mil"},{"name":"Jayme Fletcher","role":"secondary","email":"jayme.l.fletcher2.civ@health.mil"}],"base_type":{"code":"s","label":"Special Notice"},"notice_id":"7372a4d602a8425ea92dc76d5f92cb24","provenance":{"extract":{"url":"https://s3.amazonaws.com/falextracts/Contract%20Opportunities/Archived%20Data/FY2026_archived_opportunities.csv","etag":"\"d9374b90a938e9923d910594731b7b57-106\"","fetched_at":"2026-09-16T17:48:36.003679Z","row_sha256":"3ddf8a56e3325e3f4f74d4547be8fa6053c637b08d3ec264f7eed9ccb8cec1f2","last_modified":"2026-09-13T14:50:39Z"},"updated_at":"2026-09-16T17:48:36.003679Z","first_seen_at":"2026-09-16T17:48:36.003679Z"},"description":{"text":"The Defense Health Agency Contracting Activity (DHACA) intends to modify the existing contract for an increase in service on a sole source basis In Accordance With (IAW) Federal Acquisition Regulation (FAR) part 6 to Aptagen, LLC located at 250 N Main Street, Jacobus, PA 17407 as the only responsible source that can provide the United States Army Medical Research Institute of Infectious Diseases (USAMRIID) for services. The Performance Work Statement has not changed other than to adjust the number of DNA aptamer generations being provided and adding an additional target of pseudoviruses. USAMRIID has a need to generate no less than one (1) but not to exceed four (4) DNA Aptamer Library Generation per year. These aptamer libraries will consist of ~1000 - ~10,000 targeted aptamers. These libraries target specific pseudoviruses and/or alpha-conotoxins and/or palytoxins and should be capable of broad-spectrum interactions and libraries targeting four (4) to six (6) viral targets. This is a requirement that was originally identified to support USAMRIID’s project CB11484, Development of broad-spectrum DNA aptamers to neutralize toxins. The requirement is crucial as it enables USAMRIID’s researchers to ultimately generate one (1) or more DNA aptamers capable of effectively binding and neutralizing specific toxins and viruses. This is an embryonic methodology with promising outlook for future use in the research field as this and similar strategies have not been employed at the institute previously. The services will performed in Frederick , Maryland 21702.","origin":"extract"},"notice_type":{"code":"s","label":"Special Notice"},"schema_version":1,"solicitation_number":"HT942525P0045","place_of_performance":{"zip":"21702","city":{"name":"Frederick"},"state":{"code":"MD"},"country":{"code":"USA"}},"product_service_code":"AN22"}],"due_at":"2026-01-06T18:00:00Z","due_date":"2026-01-06","closes_at":"2026-01-06T18:00:00Z","awardable":false,"dept_key":"d-097","dept_name":"DEPT OF DEFENSE","sub_key":"s-97DH","sub_name":"DEFENSE HEALTH AGENCY (DHA)","office_key":"o-n-DEFENSEHEALTHAGENCYDHA","office_name":"DEFENSE HEALTH AGENCY (DHA)","state":"MD","county":"24021","county_name":"Frederick County","city":"2430325","city_name":"Frederick","country":"USA","winner_key":"HEK9BF17MKL3","amount":"582660.00","linked_awards":4,"cancelled":false,"archived":false,"updated_at":"2026-09-16T21:18:12.857524Z","principal_notice_id":"7372a4d602a8425ea92dc76d5f92cb24","description":{"text":"The Defense Health Agency Contracting Activity (DHACA) intends to modify the existing contract for an increase in service on a sole source basis In Accordance With (IAW) Federal Acquisition Regulation (FAR) part 6 to Aptagen, LLC located at 250 N Main Street, Jacobus, PA 17407 as the only responsible source that can provide the United States Army Medical Research Institute of Infectious Diseases (USAMRIID) for services. The Performance Work Statement has not changed other than to adjust the number of DNA aptamer generations being provided and adding an additional target of pseudoviruses. USAMRIID has a need to generate no less than one (1) but not to exceed four (4) DNA Aptamer Library Generation per year. These aptamer libraries will consist of ~1000 - ~10,000 targeted aptamers. These libraries target specific pseudoviruses and/or alpha-conotoxins and/or palytoxins and should be capable of broad-spectrum interactions and libraries targeting four (4) to six (6) viral targets. This is a requirement that was originally identified to support USAMRIID’s project CB11484, Development of broad-spectrum DNA aptamers to neutralize toxins. The requirement is crucial as it enables USAMRIID’s researchers to ultimately generate one (1) or more DNA aptamers capable of effectively binding and neutralizing specific toxins and viruses. This is an embryonic methodology with promising outlook for future use in the research field as this and similar strategies have not been employed at the institute previously. The services will performed in Frederick , Maryland 21702.","html":null,"origin":"extract"},"contacts":[{"name":"Christina Lewis","role":"primary","email":"christina.m.lewis14.civ@health.mil"},{"name":"Jayme Fletcher","role":"secondary","email":"jayme.l.fletcher2.civ@health.mil"}],"place_of_performance":{"zip":"21702","city":{"name":"Frederick"},"state":{"code":"MD"},"country":{"code":"USA"}},"office_address":null,"naics_codes":["325413"],"award":null,"attachments":[],"awards":[{"award_key":"CONT_AWD_HT942525P0045_9700_-NONE-_-NONE-","permalink":"https://www.usaspending.gov/award/CONT_AWD_HT942525P0045_9700_-NONE-_-NONE-/","piid":"HT942525P0045","parent_piid":null,"award_type":"PURCHASE ORDER","vendor_key":"HEK9BF17MKL3","recipient_name":"APTAGEN LLC","recipient_uei":"HEK9BF17MKL3","recipient_cage":"436H7","recipient_city":"JACOBUS","recipient_state":"PA","sub_name":"Defense Health Agency","office_name":"ARMY MED RES ACQ ACTIVITY","office_key":"o-HT9425","first_action_date":"2025-03-25","last_action_date":"2025-06-26","actions":3,"obligated":"194220.00","current_total_value":"194220.00","potential_total_value":"582660.00","naics":"325413","psc":"AN22","extent_competed":"NOT COMPETED UNDER SAP","set_aside":"NO SET ASIDE USED.","offers_received":1,"description":"DEOXYRIBONUCLEIC ACID (DNA) APTAMER LIBRARY GENERATION SERVICES","method":"piid","confidence":"high","evidence":["award number HT942525P0045 equals the contract number","same awarding office HT9425"],"opportunity_key":null,"opportunity_title":null}],"related":[]}