# CoasterChase

Canonical: https://abierto.us/opportunities/hr001125s0014

- Solicitation number: HR001125S0014
- Notice type: Solicitation
- Status: Closed. Deadline was August 28, 2025
- Department: Department of Defense
- Agency: Defense Advanced Research Projects Agency
- Contracting office: Def Advanced Research Projects Agcy (HR0011)
- NAICS: 541714 Research and Development in Biotechnology (except Nanobiotechnology)
- Product or service code: AC12 National Defense R&D Services; Department Of Defense - Military; Applied Research
- First posted: June 26, 2025
- Last posted: August 12, 2025
- SAM.gov: https://sam.gov/workspace/contract/opp/b240a74798c5464681b765ab851b1c28/view

## Description

The Defense Advanced Research Projects Agency (DARPA) is soliciting innovative proposals that leverage a novel understanding of the enteric nervous system as well as emerging neuromodulation technologies to selectively target neurons in the small intestine and alter the body’s stress response. The CoasterChase program aims to develop a multimodal, ingestible, sensing and stimulation platform for use in monitoring and modulating biomarkers of acute stress from within the small intestine.

Proposed research should investigate innovative approaches that enable revolutionary advances in enteric neuromodulation and sensing, ingestible electronics, and modulation of the stress response. Specifically excluded is research that primarily results in evolutionary improvements to the existing state of practice.

## Publications

- June 26, 2025: Solicitation, due August 28, 2025. Notice 82431f9c8fb14f73bfd8202a06391a03. https://sam.gov/workspace/contract/opp/82431f9c8fb14f73bfd8202a06391a03/view
- August 12, 2025: Solicitation, due August 28, 2025. Notice b240a74798c5464681b765ab851b1c28. https://sam.gov/workspace/contract/opp/b240a74798c5464681b765ab851b1c28/view

## Points of contact

- Pedro Irazoqui, CoasterChase@darpa.mil

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Source: SAM.gov Contract Opportunities bulk extract. Confirm deadlines on SAM.gov before responding. Cite https://abierto.us/opportunities/hr001125s0014.