# Sprague-Dawley rats (Charles River)

Canonical: https://abierto.us/opportunities/fda130321

- Solicitation number: FDA-130321
- Notice type: Special notice
- Status: Closed. Deadline was July 18, 2025 at 3:00 PM EDT
- Department: Department of Health and Human Services
- Agency: Food and Drug Administration
- Contracting office: FDA Office of Acq Grant SVCS (75F401)
- NAICS: 112930 Fur-Bearing Animal and Rabbit Production
- Product or service code: 8820 Live Animals, Not Raised for Food
- First posted: July 14, 2025
- Last posted: July 14, 2025
- SAM.gov: https://sam.gov/workspace/contract/opp/35f9b14ce93b44a1b327bb62ee2599e5/view

## Description

See attached Notice of Intent to Sole Source requirement for Sprague Dawley rats for protocols: E07877.01 and E07876.01 to access the toxicity of tobacco derived nicotine after repeated inhalation. Both studies will provide robust scientific data that will be used to identify and assess potential public health concerns related to nicotine inhalation exposures.

This acquisition is restricted to Charles River Laboratories as these same rats were provided by Charles River for the methods development for the aforementioned approved protocols and it is imperative the lab continues using this specific strain from Charles River to ensure all behavioral testing and scientific data interpretation can be compared in ongoing research.

A change in strain and supplier would result in invalidation of the studies of which any initial efforts will essentially be uninformative, unpublishable, nor can the results be used to support regulatory activities.

## Publications

- July 14, 2025: Special notice, due July 18, 2025 at 3:00 PM EDT. Notice 35f9b14ce93b44a1b327bb62ee2599e5. https://sam.gov/workspace/contract/opp/35f9b14ce93b44a1b327bb62ee2599e5/view

## Points of contact

- Suzanne Martella, suzanne.martella@fda.hhs.gov, 8705437540

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Source: SAM.gov Contract Opportunities bulk extract. Confirm deadlines on SAM.gov before responding. Cite https://abierto.us/opportunities/fda130321.
