# BARDA DRIVe EZ-BAA (EZBAA - 22-100-SOL-00003) Canonical: https://abierto.us/opportunities/driveezbaa22100sol00003 - Solicitation number: DRIVeEZBAA22100SOL00003 - Notice type: Solicitation - Status: Open. Offers due October 18, 2027 at 4:30 PM EDT - Department: Department of Health and Human Services - Agency: Office of Assistant Secretary for Preparedness and Response - Contracting office: Barda - Aspr / Daappo / Barda DCMA (75A501) - NAICS: 541714 Research and Development in Biotechnology (except Nanobiotechnology) - Product or service code: AN13 Health R&D Services; Health Care Services; Experimental Development - First posted: January 4, 2024 - Last posted: April 22, 2025 - SAM.gov: https://sam.gov/workspace/contract/opp/e9c36b10ee634987ae95d8918a728e37/view ## Description This announcement serves as a reissuance of the BARDA DRIVe EZ-BAA, now known as EZ-BAA-22-100-SOL-00003. This announcement hereby supersedes and replaces prior iterations of the BARDA DRIVe EZ-BAA (e.g. BAA-20-100-SOL-0002). Please reference the attached announcement and applicable amendments for specifics. Additionally, please visit https://drive.hhs.gov/. **Amendment 001:** This amendment to the EZBAA hereby opens the following research areas of interest ("AOI"). Please review the amendment for details of each AOI, including closing dates: **AOI #15:** **ReDIRECT AOI #16:** **Lab at Home AOI #17:** **Digital MCMs AOI #18:** **Host-Directed Therapeutics AOI #19:** **Healing Lungs AOI #20:** **DRIVe Forward AOI #21:** **Vaccines on Demand AOI #22:** **ReBooT AOI #23:** Host-Based Diagnostics 11/8/22 - Please see Amendment 002 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Adding the the following Area of Interest (AOI): **AOI #24:** REPAIR 2. Clarifying an adminstrative error. 11/14/22 - Please see Amendment 003 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Revising the following Area of Interest (AOI): **AOI #19:** Healing Lungs 12/15/22 - Please see Amendment 004 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Updating the closing date for the following Area of Interest (AOI): **AOI #21:** Vaccines on Demand 1/11/23 - Please see Amendment 005 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Pausing the following Area of Interest (AOI) by establishing a new closing date of February 15, 2023 at 12:00PM ET: **AOI #15:** ReDIRECT 2/1/23 - Please see Amendment 006 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Updating the closing date for the following Area of Interest (AOI): **AOI #19:** Healing Lungs 2. Updating the closing date for the following Area of Interest (AOI): **AOI #17:** Digital MCMs 3. Updating the closing date for the following Area of Interest (AOI): **AOI #16:** Lab at Home 4. Revising the following Area of Interest (AOI): **AOI #16:** Lab at Home 2/3/23 - Please see Amendment 007 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Updating the closing date for the following Area of Interest (AOI): **AOI #24:** REPAIR 5/1/23 - Please see Amendment 008 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Adding the following Area of Interest (AOI): **AOI #25:** FASTx 2. Updating the language in Section III (F) of the Easy Broad Agency Announcement titled “Plus (+) Phase”. 5/18/23 - Please see Amendment 009 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Reopening the following Area of Interest (AOI), which is reopened to support project Next Gen: **AOI #21:** Vaccines on Demand 5/25/23 - Please see Amendment 010 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Revising the following Area of Interest (AOI): **AOI #24:** REPAIR 2. Updating the closing date for the following Area of Interest (AOI): **AOI #24:** REPAIR 6/27/23 - Please see Amendment 011 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Closing the following Area of Interest (AOI): **AOI #18:** Host-Directed Therapeutics 2. Closing the following Area of Interest (AOI): **AOI #23:** Host-Based Diagnostics 3. Updating the closing date for the following Area of Interest (AOI): **AOI #19:** Healing Lungs 9/13/23 - Please see Amendment 012 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Updating the closing date for the following Area of Interest (AOI): **AOI #16:** Lab at Home 2. Updating the closing date for the following Area of Interest (AOI): **AOI #17:** Digital MCMs 3. Updating the closing date for the following Area of Interest (AOI): **AOI #19:** Healing Lungs 4. Revising the following Area of Interest (AOI): AOI #16 Lab at Home 5. Adding the following Area of Interest (AOI): **AOI #26:** Agnostic Diagnostic 9/14/23 - Please see Amendment 013 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Pausing the following Area of Interest (AOI): **AOI #20:** DRIVe Forward 9/26/23 - Please see Amendment 014 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Pausing the following Area of Interest (AOI): **AOI #21:** Vaccines on Demand 10/26/23 - Please see Amendment 015 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Updating the closing date for the following Area of Interest (AOI): **AOI #22:** ReBoot 2. Updating the closing date for the following Area of Interest (AOI): **AOI #25:** FASTx 3. Revising the following Area of Interest (AOI): **AOI #22:** ReBoot 4. Revising the following Area of Interest (AOI): **AOI #25:** FASTx 10/30/23 - Please see Amendment 016 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Pausing the following Area of Interest (AOI): **AOI #24:** REPAIR 11/15/23 - Please see Amendment 017 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Reopening the following Area of Interest (AOI): **AOI #20:** DRIVe Forward 2. Revising the following Area of Interest (AOI): **AOI #20:** DRIVe Forward 12/13/23 - Please see Amendment 018 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Updating the closing date for the following Area of Interest (AOI): **AOI #16:** Lab at Home 2. Revising the following Area of Interest (AOI): **AOI #16:** Lab at Home 3. Pausing the following Area of Interest (AOI): **AOI #17:** Digital MCMs 4. Updating the closing date for the following Area of Interest (AOI): **AOI #19:** Healing Lungs 01/03/24 - Please see Amendment 019 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Reopening the following Area of Interest (AOI): **AOI #15:** ReDIRECT 2. Revising the following Area of Interest (AOI): **AOI #15:** ReDIRECT 01/10/24 - Please see Amendment 020 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Pausing the following Area of Interest (AOI): **AOI #26:** Agnostic Diagnostic 2. Adding a topic to the following Area of Interest (AOI): **AOI #20:** DRIVe Forward 3. Updating the closing date for the following Area of Interest (AOI): **AOI #20:** DRIVe Forward 01/18/24 - Please see Amendment 021 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Adding the following Area of Interest (AOI): **AOI #27:** Stopping Secondary Spread 2/5/24 - Please see Amendment 022 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Pausing the following research Area of Interest (AOI): **AOI #27:** Stopping Secondary Spread 2. Revise topics for the following research Area of Interest (AOI): **AOI #20:** DRIVe Forward 02/12/24 - Please see Amendment 023 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Reopening the following Area of Interest (AOI): **AOI #26:** Agnostic Diagnostic 02/21/24 - Please see Amendment 024 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Updating the closing date for the following Area of Interest (AOI): **AOI #22:** ReBooT 2. Updating the closing date for the following Area of Interest (AOI): **AOI #25:** FASTx 03/04/24 - Please see Amendment 025 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Reopening the following Area of Interest (AOI): **AOI #24:** RePAIR 2. Revising the following Area of Interest (AOI): **AOI #24:** RePAIR 03/12/24 - Please see Amendment 026 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Updating the closing date for the following Area of Interest (AOI): **AOI #16:** Lab at Home 2. Updating the closing date for the following Area of Interest (AOI): **AOI #19:** Healing Lungs 04/22/24 - Please see Amendment 027 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Reopening the following Area of Interest (AOI): **AOI #20:** DRIVe Forward 2. Removing two topic areas and adding one topic area to the following Area of Interest (AOI): **AOI #20:** DRIVe Forward 05/01/24 - Please see Amendment 028 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Updating the closing date for the following Area of Interest (AOI): **AOI #15:** ReDIRECT 2. Updating the closing date for the following Area of Interest (AOI): **AOI #26:** Agnostic Diagnostic 3. Reopening the following Area of Interest (AOI): **AOI #17:** Digital MCMs 4. Revising the following Area of Interest (AOI): **AOI #17:** Digital MCMs 05/09/24 - Please see Amendment 029 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Pausing the following Area of Interest (AOI): **AOI #16:** Lab at Home 2. Updating the closing date for the following Area of Interest (AOI): **AOI #19:** Healing Lungs 3. Revising the following Area of Interest (AOI): **AOI #19:** Healing Lungs 4. Updating the closing date for the following Area of Interest (AOI): **AOI #24:** RePAIR 09/24/24 - Please see Amendment 030 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Adding the following Area of Interest (AOI): **AOI #28:** Influenza Vaccine Innovation 2. Pausing the following Area of Interest (AOI): **AOI #26:** Agnostic Diagnostic 09/30/24 - Please see Amendment 031 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Reopening the following Area of Interest (AOI): **AOI #24:** RePAIR 10/10/24 - Please see Amendment 032 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: Update the closing date for the following Area of Interest (AOI): **AOI #19:** Healing Lungs Pause the following Area of Interest (AOI) on 10/31/24: **AOI #17:** Digital MCMs 10/31/24 - Please see Amendment 033 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: Reopen the following Area of Interest (AOI) on 11/1/24: **AOI #15:** ReDIRECT 2. Remove language requiring a Rough Order of Magnitude (ROM) from the record 11/26/2024 - Please see Amendment 034 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1) Reopen the following Area of Interest (AOI): **AOI #22:** ReBooT 2) Revise the following Area of Interest (AOI): **AOI #22:** ReBooT 3) Pause the following Area of Interest (AOI): **AOI#24:** RePAIR 1/13/2025 - Please see Amendment 035 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1) Reopen the following Area of Interest (AOI) on 1/15/2025: **AOI #16:** Lab at Home 2) Open the following Area of Interest (AOI): **AOI #29:** Type to Treat 2/14/2025 - Please see Amendment 036 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: Updating the closing date for the following Area of Interest (AOI): **AOI #19:** Healing Lung 4/22/2025 - Please see Amendment 037 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this amendment, BARDA is revising the following Areas of Interest (AOI) to close effective immediately: **AOI #19:** **Healing Lungs AOI #20:** **ReBooT AOI #29:** Type to Treat Additional details can be found in the corresponding Amendment 037. ## Publications - January 4, 2024: Solicitation, due October 18, 2027 at 4:30 PM EDT. Notice 722c80b5e171433b9f4747a6fdd64320. https://sam.gov/workspace/contract/opp/722c80b5e171433b9f4747a6fdd64320/view - January 8, 2024: Solicitation, due October 18, 2027 at 4:30 PM EDT. Notice 6e928b9606d24e37b65a6751b69559df. https://sam.gov/workspace/contract/opp/6e928b9606d24e37b65a6751b69559df/view - January 10, 2024: Solicitation, due October 18, 2027 at 4:30 PM EDT. Notice f7252d9bd4c146dcb16014a5e33b6564. https://sam.gov/workspace/contract/opp/f7252d9bd4c146dcb16014a5e33b6564/view - January 19, 2024: Solicitation, due October 18, 2027 at 4:30 PM EDT. Notice f356e2d2aa384a998e3c3e461e279416. https://sam.gov/workspace/contract/opp/f356e2d2aa384a998e3c3e461e279416/view - February 5, 2024: Solicitation, due October 18, 2027 at 4:30 PM EDT. Notice ab3583fbb9b248a7b0889bf02050b441. https://sam.gov/workspace/contract/opp/ab3583fbb9b248a7b0889bf02050b441/view - February 12, 2024: Solicitation, due October 18, 2027 at 4:30 PM EDT. Notice d9a40e124a8c4c5f8efa8fc1ad31703f. https://sam.gov/workspace/contract/opp/d9a40e124a8c4c5f8efa8fc1ad31703f/view - February 26, 2024: Solicitation, due October 18, 2027 at 4:30 PM EDT. Notice 859f6ff8f02b4000919c396c3dab5946. https://sam.gov/workspace/contract/opp/859f6ff8f02b4000919c396c3dab5946/view - March 4, 2024: Solicitation, due October 18, 2027 at 4:30 PM EDT. Notice ca58787ca10b4ee281524f1e6f805ed9. https://sam.gov/workspace/contract/opp/ca58787ca10b4ee281524f1e6f805ed9/view - March 12, 2024: Solicitation, due October 18, 2027 at 4:30 PM EDT. Notice acb2fc60fc434f239241bfc63e2e97a6. https://sam.gov/workspace/contract/opp/acb2fc60fc434f239241bfc63e2e97a6/view - April 24, 2024: Solicitation, due October 18, 2027 at 4:30 PM EDT. Notice 9bdcae8d320040fa9b074dc3bd7752d8. https://sam.gov/workspace/contract/opp/9bdcae8d320040fa9b074dc3bd7752d8/view - May 1, 2024: Solicitation, due October 18, 2027 at 4:30 PM EDT. Notice 4ab24f470f6f4cad84ad1bb2065d35ea. https://sam.gov/workspace/contract/opp/4ab24f470f6f4cad84ad1bb2065d35ea/view - May 9, 2024: Solicitation, due October 18, 2027 at 4:30 PM EDT. Notice 5d6a4e1582c444b196dbef185231f74e. https://sam.gov/workspace/contract/opp/5d6a4e1582c444b196dbef185231f74e/view - September 24, 2024: Solicitation, due October 18, 2027 at 4:30 PM EDT. Notice d146d63996b84d08a4cd963ef5bf2bd4. https://sam.gov/workspace/contract/opp/d146d63996b84d08a4cd963ef5bf2bd4/view - September 30, 2024: Solicitation, due October 18, 2027 at 4:30 PM EDT. Notice a01f0468716d4a6f82befdc0838c8d77. https://sam.gov/workspace/contract/opp/a01f0468716d4a6f82befdc0838c8d77/view - October 11, 2024: Solicitation, due October 18, 2027 at 4:30 PM EDT. Notice 3881960689394a409a4421f993f8ab82. https://sam.gov/workspace/contract/opp/3881960689394a409a4421f993f8ab82/view - October 31, 2024: Solicitation, due October 18, 2027 at 4:30 PM EDT. Notice 1af712dc77c347e2841eff3bb91f6331. https://sam.gov/workspace/contract/opp/1af712dc77c347e2841eff3bb91f6331/view - November 26, 2024: Solicitation, due October 18, 2027 at 4:30 PM EDT. Notice 8f4d63db541c46ff9e339d8c43d0ad86. https://sam.gov/workspace/contract/opp/8f4d63db541c46ff9e339d8c43d0ad86/view - January 13, 2025: Solicitation, due October 18, 2027 at 4:30 PM EDT. Notice a6d9e0f6955b416183030a3c742d895f. https://sam.gov/workspace/contract/opp/a6d9e0f6955b416183030a3c742d895f/view - February 14, 2025: Solicitation, due October 18, 2027 at 4:30 PM EDT. Notice 6684d4a2734047d58d6cbf7e50bdd00a. https://sam.gov/workspace/contract/opp/6684d4a2734047d58d6cbf7e50bdd00a/view - April 22, 2025: Solicitation, due October 18, 2027 at 4:30 PM EDT. Notice 42afa51fe02949309a6bdd4ce111f1c4. https://sam.gov/workspace/contract/opp/42afa51fe02949309a6bdd4ce111f1c4/view - April 22, 2025: Solicitation, due October 18, 2027 at 4:30 PM EDT. Notice e9c36b10ee634987ae95d8918a728e37. https://sam.gov/workspace/contract/opp/e9c36b10ee634987ae95d8918a728e37/view ## Points of contact - BARDA DCMA DRIVe Team, DRIVeAcquisitions@hhs.gov --- Source: SAM.gov Contract Opportunities bulk extract. Confirm deadlines on SAM.gov before responding. Cite https://abierto.us/opportunities/driveezbaa22100sol00003.