# Non-Optical Methods for High Speed Protein Control

Canonical: https://abierto.us/opportunities/darpasn2689

- Solicitation number: DARPA-SN-26-89
- Notice type: Special notice
- Status: Closed. Deadline was December 31, 2026 at 11:59 PM EST
- Department: Department of Defense
- Agency: Defense Advanced Research Projects Agency
- Contracting office: Def Advanced Research Projects Agcy (HR0011)
- NAICS: 541714 Research and Development in Biotechnology (except Nanobiotechnology)
- Product or service code: AC12 National Defense R&D Services; Department Of Defense - Military; Applied Research
- First posted: July 21, 2026
- Last posted: July 21, 2026
- SAM.gov: https://sam.gov/workspace/contract/opp/834caaf2b61048afb84a252010027b34/view

## Description

**UPDATE:** The purpose of Amendment 1 to DARPA-SN-26-89, the Non-Optical Methods for High Speed Protein Control Special Notice (SN), is to clarify the notice deadline. DARPA BTO will be actively “shopping” the ERIS Marketplace for innovative, post-competitive, awardable solutions that address the need for a new class of rapidly switchable, non-optogenetic protein domains for real-time cellular control. This effort seeks to develop a robust and versatile molecular tool for massless information transfer across a cell membrane, intended to supplement existing synthetic biology platforms.

## Publications

- July 21, 2026: Special notice, due December 31, 2026. Notice 406c91d063494363aee2746d5fe476df. https://sam.gov/workspace/contract/opp/406c91d063494363aee2746d5fe476df/view
- July 21, 2026: Special notice, due December 31, 2026 at 11:59 PM EST. Notice 834caaf2b61048afb84a252010027b34. https://sam.gov/workspace/contract/opp/834caaf2b61048afb84a252010027b34/view

## Points of contact

- Dr. Jeffrey Zaleski, DARPA/BTO, ERIS@darpa.mil

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Source: SAM.gov Contract Opportunities bulk extract. Confirm deadlines on SAM.gov before responding. Cite https://abierto.us/opportunities/darpasn2689.