{"canonical":"https://abierto.us/opportunities/darpasn2666","key":"DARPASN2666","url":"https://abierto.us/opportunities/darpasn2666","title":"Request for Information: Biomolecule Purification","solicitation_number":"DARPA-SN-26-66","notice_type":"s","open":false,"response_deadline":"2026-06-08","first_posted":"2026-05-15","last_posted":"2026-05-21","department":"DEPT OF DEFENSE","subagency":"DEFENSE ADVANCED RESEARCH PROJECTS AGENCY (DARPA)","office":"DEF ADVANCED RESEARCH PROJECTS AGCY","naics":"541715","psc":"AC12","set_aside":null,"place_state":null,"place_county":null,"place_county_name":null,"place_city":null,"place_city_name":null,"winner":null,"award_amount":null,"publications":[{"notice_id":"e69e8e0fd537432f81d23cf4d38faee5","title":"Request for Information: Biomolecule Purification","solicitation_number":"DARPA-SN-26-66","notice_type":"s","base_type":"s","posted":"2026-05-15","posted_at":null,"due_at":null,"due_date":"2026-06-08","cancelled":null,"archived":null,"archive_date":"2026-06-10","award_number":null,"awardee_name":null,"amount":null,"link_sam":"https://sam.gov/workspace/contract/opp/e69e8e0fd537432f81d23cf4d38faee5/view","enriched":false,"history":[]},{"notice_id":"b8e73bf9adcb4c62a0da544d64795ef9","title":"Request for Information: Biomolecule Purification","solicitation_number":"DARPA-SN-26-66","notice_type":"s","base_type":"s","posted":"2026-05-21","posted_at":null,"due_at":null,"due_date":"2026-06-08","cancelled":null,"archived":null,"archive_date":"2026-06-10","award_number":null,"awardee_name":null,"amount":null,"link_sam":"https://sam.gov/workspace/contract/opp/b8e73bf9adcb4c62a0da544d64795ef9/view","enriched":false,"history":[]}],"latest_notice_id":"b8e73bf9adcb4c62a0da544d64795ef9","first_type":"s","notices":[{"dates":{"posted":"2026-05-15","response_deadline":{"raw":"2026-06-08T17:00:00","date":"2026-06-08","time":"17:00:00"}},"links":{"sam":"https://sam.gov/workspace/contract/opp/e69e8e0fd537432f81d23cf4d38faee5/view"},"naics":{"codes":["541715"],"primary":"541715"},"title":"Request for Information: Biomolecule Purification","agency":{"office":{"code":"HR0011","name":"DEF ADVANCED RESEARCH PROJECTS AGCY"},"subtier":{"code":"97AE","name":"DEFENSE ADVANCED RESEARCH PROJECTS AGENCY (DARPA)"},"department":{"code":"097","name":"DEPT OF DEFENSE"},"office_address":{"zip":"222032114","city":"ARLINGTON","state":"VA","country":"USA"},"organization_type":"OFFICE"},"status":{"active":false,"archive_date":"2026-06-10","archive_type":"auto_custom"},"contacts":[{"name":"DARPA-SN-26-66 Coordinator","role":"primary","email":"DARPA-SN-26-66@darpa.mil"}],"base_type":{"code":"s","label":"Special Notice"},"notice_id":"e69e8e0fd537432f81d23cf4d38faee5","provenance":{"extract":{"url":"https://s3.amazonaws.com/falextracts/Contract%20Opportunities/Archived%20Data/FY2026_archived_opportunities.csv","etag":"\"d9374b90a938e9923d910594731b7b57-106\"","fetched_at":"2026-09-16T16:22:53.920682Z","row_sha256":"d494ee220d7a159d23eb89c98c96f6e946e431d722737b08f70864a67738d3c3","last_modified":"2026-09-13T14:50:39Z"},"updated_at":"2026-09-16T16:22:53.920682Z","first_seen_at":"2026-09-16T16:22:53.920682Z"},"description":{"text":"The Defense Advanced Research Projects Agency (DARPA) Microsystems Technology Office (MTO) seeks information on novel methods for the purification of large complex molecules that will enable the creation of a universal purification platform capable of separating and recovering multiple large and complex molecules with high specificity, purity, and yield from complex feedstock. It is anticipated that such a platform will decrease the time and complexity of purification and eliminate the need for multistep chromatography processes, which DARPA believes to be the state of the art. In addition, this RFI seeks to understand a) the current advances and challenges in the purification of biologically produced proteins, as well as of other critical biologically produced molecules that could benefit from a novel purification approach, and b) new operational capabilities enabled by novel purification approaches. Responses to this RFI will be used to inform the development of a new program.","origin":"extract"},"notice_type":{"code":"s","label":"Special Notice"},"schema_version":1,"solicitation_number":"DARPA-SN-26-66","product_service_code":"AC12"},{"dates":{"posted":"2026-05-21","response_deadline":{"raw":"2026-06-08T17:00:00","date":"2026-06-08","time":"17:00:00"}},"links":{"sam":"https://sam.gov/workspace/contract/opp/b8e73bf9adcb4c62a0da544d64795ef9/view"},"naics":{"codes":["541715"],"primary":"541715"},"title":"Request for Information: Biomolecule Purification","agency":{"office":{"code":"HR0011","name":"DEF ADVANCED RESEARCH PROJECTS AGCY"},"subtier":{"code":"97AE","name":"DEFENSE ADVANCED RESEARCH PROJECTS AGENCY (DARPA)"},"department":{"code":"097","name":"DEPT OF DEFENSE"},"office_address":{"zip":"222032114","city":"ARLINGTON","state":"VA","country":"USA"},"organization_type":"OFFICE"},"status":{"active":false,"archive_date":"2026-06-10","archive_type":"auto_custom"},"contacts":[{"name":"DARPA-SN-26-66 Coordinator","role":"primary","email":"DARPA-SN-26-66@darpa.mil"}],"base_type":{"code":"s","label":"Special Notice"},"notice_id":"b8e73bf9adcb4c62a0da544d64795ef9","provenance":{"extract":{"url":"https://s3.amazonaws.com/falextracts/Contract%20Opportunities/Archived%20Data/FY2026_archived_opportunities.csv","etag":"\"d9374b90a938e9923d910594731b7b57-106\"","fetched_at":"2026-09-16T16:22:53.920682Z","row_sha256":"02f27c303c97f75776d579e8e7ced300f1b0e4cdf70ddba6e4fde29681270b19","last_modified":"2026-09-13T14:50:39Z"},"updated_at":"2026-09-16T16:22:53.920682Z","first_seen_at":"2026-09-16T16:22:53.920682Z"},"description":{"text":"The Defense Advanced Research Projects Agency (DARPA) Multi X Office (MXO) seeks information on novel methods for the purification of large complex molecules that will enable the creation of a universal purification platform capable of separating and recovering multiple large and complex molecules with high specificity, purity, and yield from complex feedstock. It is anticipated that such a platform will decrease the time and complexity of purification and eliminate the need for multistep chromatography processes, which DARPA believes to be the state of the art. In addition, this RFI seeks to understand a) the current advances and challenges in the purification of biologically produced proteins, as well as of other critical biologically produced molecules that could benefit from a novel purification approach, and b) new operational capabilities enabled by novel purification approaches. Responses to this RFI will be used to inform the development of a new program.","origin":"extract"},"notice_type":{"code":"s","label":"Special Notice"},"schema_version":1,"solicitation_number":"DARPA-SN-26-66","product_service_code":"AC12"}],"due_at":null,"due_date":"2026-06-08","closes_at":"2026-06-09T00:00:00Z","awardable":false,"dept_key":"d-097","dept_name":"DEPT OF DEFENSE","sub_key":"s-97AE","sub_name":"DEFENSE ADVANCED RESEARCH PROJECTS AGENCY (DARPA)","office_key":"o-HR0011","office_name":"DEF ADVANCED RESEARCH PROJECTS AGCY","state":null,"county":null,"county_name":null,"city":null,"city_name":null,"country":null,"winner_key":null,"amount":null,"linked_awards":0,"cancelled":false,"archived":false,"updated_at":"2026-09-16T21:18:12.857524Z","principal_notice_id":"b8e73bf9adcb4c62a0da544d64795ef9","description":{"text":"The Defense Advanced Research Projects Agency (DARPA) Multi X Office (MXO) seeks information on novel methods for the purification of large complex molecules that will enable the creation of a universal purification platform capable of separating and recovering multiple large and complex molecules with high specificity, purity, and yield from complex feedstock. It is anticipated that such a platform will decrease the time and complexity of purification and eliminate the need for multistep chromatography processes, which DARPA believes to be the state of the art. In addition, this RFI seeks to understand a) the current advances and challenges in the purification of biologically produced proteins, as well as of other critical biologically produced molecules that could benefit from a novel purification approach, and b) new operational capabilities enabled by novel purification approaches. Responses to this RFI will be used to inform the development of a new program.","html":null,"origin":"extract"},"contacts":[{"name":"DARPA-SN-26-66 Coordinator","role":"primary","email":"DARPA-SN-26-66@darpa.mil"}],"place_of_performance":null,"office_address":{"zip":"222032114","city":"ARLINGTON","state":"VA","country":"USA"},"naics_codes":["541715"],"award":null,"attachments":[],"awards":[],"related":[{"key":"DARPAPS26127","latest_notice_id":"8b8a67ca341440198bb3e5d8c4786454","title":"Perrseus","solicitation_number":"DARPA-PS-26-127","notice_type":"o","first_type":"o","first_posted":"2026-07-15","last_posted":"2026-09-14","notices":15,"due_at":null,"due_date":"2026-09-23","closes_at":"2026-09-24T00:00:00Z","awardable":true,"open":true,"dept_key":"d-097","dept_name":"DEPT OF DEFENSE","sub_key":"s-97AE","sub_name":"DEFENSE ADVANCED RESEARCH PROJECTS AGENCY (DARPA)","office_key":"o-HR0011","office_name":"DEF ADVANCED RESEARCH PROJECTS AGCY","naics":"541715","psc":"AC12","set_aside":null,"state":null,"county":null,"county_name":null,"city":null,"city_name":null,"country":null,"winner":null,"winner_key":null,"amount":null,"linked_awards":0,"cancelled":false,"archived":false,"updated_at":"2026-09-16T21:18:12.857524Z"},{"key":"HR001126S0003","latest_notice_id":"8d403582edfd409795560247e8d229b7","title":"Biological Technologies","solicitation_number":"HR001126S0003","notice_type":"o","first_type":"o","first_posted":"2025-10-01","last_posted":"2025-10-01","notices":1,"due_at":null,"due_date":"2026-09-30","closes_at":"2026-10-01T00:00:00Z","awardable":true,"open":true,"dept_key":"d-097","dept_name":"DEPT OF DEFENSE","sub_key":"s-97AE","sub_name":"DEFENSE ADVANCED RESEARCH PROJECTS AGENCY (DARPA)","office_key":"o-HR0011","office_name":"DEF ADVANCED RESEARCH PROJECTS AGCY","naics":"541714","psc":"AC11","set_aside":null,"state":null,"county":null,"county_name":null,"city":null,"city_name":null,"country":null,"winner":null,"winner_key":null,"amount":null,"linked_awards":0,"cancelled":false,"archived":false,"updated_at":"2026-09-16T21:18:12.857524Z"},{"key":"HR001126S0016","latest_notice_id":"5b497934e0474b72bbf7e03d8babb571","title":"Precision Inertial Navigation & Positioning On an Integrated Tesseract (PINPOINT)","solicitation_number":"HR001126S0016","notice_type":"o","first_type":"o","first_posted":"2026-08-06","last_posted":"2026-09-10","notices":3,"due_at":null,"due_date":"2026-10-02","closes_at":"2026-10-03T00:00:00Z","awardable":true,"open":true,"dept_key":"d-097","dept_name":"DEPT OF DEFENSE","sub_key":"s-97AE","sub_name":"DEFENSE ADVANCED RESEARCH PROJECTS AGENCY (DARPA)","office_key":"o-HR0011","office_name":"DEF ADVANCED RESEARCH PROJECTS AGCY","naics":"541715","psc":"AC12","set_aside":null,"state":null,"county":null,"county_name":null,"city":null,"city_name":null,"country":null,"winner":null,"winner_key":null,"amount":null,"linked_awards":0,"cancelled":false,"archived":false,"updated_at":"2026-09-16T21:18:12.857524Z"},{"key":"DARPAPA250706","latest_notice_id":"3ac25ac710fb438e8d25d99783cee845","title":"Selective Harnessing of Intrinsic Neuroplasticity Engineering (SHINE)","solicitation_number":"DARPA-PA-25-07-06","notice_type":"o","first_type":"o","first_posted":"2026-08-28","last_posted":"2026-09-03","notices":2,"due_at":null,"due_date":"2026-10-09","closes_at":"2026-10-10T00:00:00Z","awardable":true,"open":true,"dept_key":"d-097","dept_name":"DEPT OF DEFENSE","sub_key":"s-97AE","sub_name":"DEFENSE ADVANCED RESEARCH PROJECTS AGENCY (DARPA)","office_key":"o-HR0011","office_name":"DEF ADVANCED RESEARCH PROJECTS AGCY","naics":"541715","psc":"AC11","set_aside":null,"state":null,"county":null,"county_name":null,"city":null,"city_name":null,"country":null,"winner":null,"winner_key":null,"amount":null,"linked_awards":0,"cancelled":false,"archived":false,"updated_at":"2026-09-16T21:18:12.857524Z"},{"key":"DARPAPA250704","latest_notice_id":"f0e3e0d303254053922d9b2c7a67e878","title":"Resilient","solicitation_number":"DARPA-PA-25-07-04","notice_type":"o","first_type":"o","first_posted":"2026-08-20","last_posted":"2026-09-04","notices":3,"due_at":null,"due_date":"2026-10-19","closes_at":"2026-10-20T00:00:00Z","awardable":true,"open":true,"dept_key":"d-097","dept_name":"DEPT OF DEFENSE","sub_key":"s-97AE","sub_name":"DEFENSE ADVANCED RESEARCH PROJECTS AGENCY (DARPA)","office_key":"o-HR0011","office_name":"DEF ADVANCED RESEARCH PROJECTS AGCY","naics":"541715","psc":"AC12","set_aside":null,"state":null,"county":null,"county_name":null,"city":null,"city_name":null,"country":null,"winner":null,"winner_key":null,"amount":null,"linked_awards":0,"cancelled":false,"archived":false,"updated_at":"2026-09-16T21:18:12.857524Z"}]}