# Future Program: Smart-Red Blood Cells (Smart-RBC)

Canonical: https://abierto.us/opportunities/darpasn25107

- Solicitation number: DARPA-SN-25-107
- Notice type: Special notice
- Status: Closed. Deadline was October 31, 2025
- Department: Department of Defense
- Agency: Defense Advanced Research Projects Agency
- Contracting office: Def Advanced Research Projects Agcy (HR0011)
- NAICS: 541714 Research and Development in Biotechnology (except Nanobiotechnology)
- Product or service code: AC12 National Defense R&D Services; Department Of Defense - Military; Applied Research
- First posted: September 10, 2025
- Last posted: September 10, 2025
- SAM.gov: https://sam.gov/workspace/contract/opp/bf64d14f7d764d979f327ed3b8de9e3b/view

## Description

The purpose of this Special Notice (SN) is to provide public notification of additional research areas of interest to the Defense Advanced Research Projects Agency (DARPA) Biological Technologies Office (BTO), specifically for the forthcoming Smart-Red Blood Cells (Smart-RBC) program. The DARPA Smart-RBC program aims to engineer red blood cells to contain novel biological features that can safely and reliably modify human physiology. Specifically, the Smart-RBC program seeks to revolutionize blood products by creating “smart red blood cells” (SRBCs).

## Publications

- September 10, 2025: Special notice, due October 31, 2025. Notice bf64d14f7d764d979f327ed3b8de9e3b. https://sam.gov/workspace/contract/opp/bf64d14f7d764d979f327ed3b8de9e3b/view

## Points of contact

- Dr. Christopher Bettinger, DARPA/BTO, Smart-RBC@darpa.mil

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Source: SAM.gov Contract Opportunities bulk extract. Confirm deadlines on SAM.gov before responding. Cite https://abierto.us/opportunities/darpasn25107.