# Organoid Cytomorphic Intelligence Resulting from Convergent Understanding and Information Transfer (O-Circuit)

Canonical: https://abierto.us/opportunities/darpaps2628

- Solicitation number: DARPA-PS-26-28
- Notice type: Solicitation
- Status: Closed. Deadline was May 20, 2026
- Department: Department of Defense
- Agency: Defense Advanced Research Projects Agency
- Contracting office: Def Advanced Research Projects Agcy (HR0011)
- NAICS: 541714 Research and Development in Biotechnology (except Nanobiotechnology)
- Product or service code: AC12 National Defense R&D Services; Department Of Defense - Military; Applied Research
- First posted: May 1, 2026
- Last posted: May 1, 2026
- SAM.gov: https://sam.gov/workspace/contract/opp/6d28dbf9da1f4fe09c58d5ad7896fe9c/view

## Description

While semiconductor-based computation is readily deployed in well-resourced environments, it is challenged by sustained applications ‘at the edge’ due to inherent power inefficiencies. This is a particular limitation for the Department of War (DoW) when operating in austere environments, especially when using advanced artificial intelligence and machine learning (AI/ML) applications with high energy demands for both training and inference.

New unconventional computing concepts, such as synthetic biological intelligence, have the potential to fundamentally address these limitations but do not yet possess the necessary training and inference capabilities for practical applications.

To meet these needs, the O-Circuit program will explore methods for improving the learning, inference, and computational memory of neural tissue systems to develop an integrated biological processing unit (BPU) that establishes a new paradigm for sense-compute-act for edge applications.

## Publications

- May 1, 2026: Solicitation, due May 20, 2026. Notice 6d28dbf9da1f4fe09c58d5ad7896fe9c. https://sam.gov/workspace/contract/opp/6d28dbf9da1f4fe09c58d5ad7896fe9c/view

## Points of contact

- Dr. Jeffrey Zaleski, Program Manager, DARPA/BTO, O-circuit@darpa.mil

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Source: SAM.gov Contract Opportunities bulk extract. Confirm deadlines on SAM.gov before responding. Cite https://abierto.us/opportunities/darpaps2628.