# Systems for Phenotypic Evaluation, Clinical Trajectories, Response, and Agency (SPECTRA)

Canonical: https://abierto.us/opportunities/arpahsol26163

- Solicitation number: ARPA-H-SOL-26-163
- Notice type: Solicitation
- Status: Open. Offers due October 18, 2026 at 5:00 PM EDT
- Department: Department of Health and Human Services
- Agency: National Institutes of Health
- Contracting office: Advanced Research Projects Agency for Health (Arpa-H) (75N992)
- NAICS: 541715 Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
- Product or service code: AN13 Health R&D Services; Health Care Services; Experimental Development
- First posted: September 17, 2026
- Last posted: September 17, 2026
- SAM.gov: https://sam.gov/workspace/contract/opp/ae0ce5edc4c341afbf26a9413cfdae62/view

## Description

SPECTRA will identify and act on autism trajectories, the evolving developmental paths individuals follow across the lifespan from the prenatal period through aging, spanning autism characteristics, co-occurring conditions, and functional outcomes together with the genetic, biological, behavioral, iatrogenic (medical influences), environmental factors and their nonlinear interactions. Rather than examining these factors in isolation, SPECTRA will examine how they combine and interact, including their nonlinear interactions, to produce autism and its co-occurring conditions over time.

SPECTRA will also develop technologies that serve two purposes at once: extending reliable assessment beyond the clinic while improving everyday communication, function, and quality of life. The same tools people use to live more fully will also generate the data that drive measurement and personalized care.

## Attachments

- [SPECTRA_Attachment A1_TA4 Solution Summary Format and Instructions.pdf](https://sam.gov/api/prod/opps/v3/opportunities/resources/files/eac2836ff28943b0a916929af798e5a0/download)

## Publications

- September 17, 2026: Solicitation, due October 18, 2026 at 5:00 PM EDT. Notice ae0ce5edc4c341afbf26a9413cfdae62. https://sam.gov/workspace/contract/opp/ae0ce5edc4c341afbf26a9413cfdae62/view

## Points of contact

- SPECTRA Team, SPECTRA@arpa-h.gov

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Source: SAM.gov Contract Opportunities bulk extract. Confirm deadlines on SAM.gov before responding. Cite https://abierto.us/opportunities/arpahsol26163.