# Final Innovative Solutions Opening (ISO) ARPA-H Rare Disease AI/ML for Precision Integrated Diagnostics (RAPID)

Canonical: https://abierto.us/opportunities/arpahsol25119

- Solicitation number: ARPA-H-SOL-25-119
- Notice type: Solicitation (first published as presolicitation)
- Status: Closed. Deadline was April 24, 2025 at 5:00 PM EDT
- Department: Department of Health and Human Services
- Agency: National Institutes of Health
- Contracting office: Advanced Research Projects Agency for Health (Arpa-H) (75N992)
- NAICS: 541715 Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
- Product or service code: AN13 Health R&D Services; Health Care Services; Experimental Development
- First posted: January 10, 2025
- Last posted: March 20, 2025
- SAM.gov: https://sam.gov/workspace/contract/opp/223414706694467e973cdfcb4041f05a/view

## Description

**20 MAR:**

**Note:** It is permissible to join as many proposals as you would like within each RAPID program TA or across TAs. While there is statutory language that may suggest ARPA-H is limited in the number of awards it may make to one entity, there are circumstances in which ARPA-H may make more than three awards to a particular person or organization. ARPA-H encourages organizations to submit their research ideas notwithstanding this perceived limitation.This guidance supersedes the limitation noted in an earlier version of the FAQs published on the RAPID program webpage and in the Proposers' Day video. Both resources have been updated accordingly.

**14 MAR:** The deadline for proposals to the RAPID program (ARPA-H-SOL-25-119) is extended to April 24, 2025 05:00 pm EDT. Feedback on Solution Summaries is expected to be sent out the week of March 17-21, 2025.

Amendment 1 changes: -The full proposal due date was extended to April 24, 2025 -All times were updated from EST to EDT Visit the RAPID Program Page for additional materials and program updates.

**21 FEB:** The RAPID Patients’ Day (ARPA-H-SN-25-127) event is now CANCELLED. The RAPID team will post a video and other information when possible. Questions sent to RAPID@arpa-h.gov will be answered as soon as the RAPID team is able to respond.

**23 JAN:** Due to circumstances outside of ARPA-H’s control, the RAPID Proposers’ Day event is now CANCELLED. Questions sent to RAPID@arpa-h.gov ARE UNABLE TO BE ANSWERED AT THIS TIME.

**22 JAN:** RAPID proposers intending to participate in the RAPID Proposers' Day are encouraged to review ARPA-H Special Notice ARPA-H-SN-25-124. Due to circumstances outside of ARPA-H’s control, the RAPID Proposers’ Day event will now occur only virtually. Verified/accepted participants are encouraged to verify they have received the Zoom link/invitation. Questions sent to RAPID@arpa-h.gov will be addressed as quickly as possible. The is the final ISO for the RAPID program.

RAPID aims to end or significantly reduce the prolonged diagnostic odysseys affecting millions of rare disease patients worldwide. RAPID seeks to develop novel diagnostic support tools for population-scale rare disease detection, systematically identifying and diagnosing rare disease patients more efficiently and accurately.

## Publications

- January 10, 2025: Presolicitation, due April 11, 2025 at 5:00 PM EDT. Notice c79e234252324d459a3081566d3bf3f8. https://sam.gov/workspace/contract/opp/c79e234252324d459a3081566d3bf3f8/view
- January 18, 2025: Solicitation, due April 11, 2025 at 5:00 PM EDT. Notice 382815eba6a34487a02bdbf8d871e842. https://sam.gov/workspace/contract/opp/382815eba6a34487a02bdbf8d871e842/view
- January 22, 2025: Solicitation, due April 11, 2025 at 5:00 PM EDT. Notice 1f44dcd191ab4855bcbe0f1e404be204. https://sam.gov/workspace/contract/opp/1f44dcd191ab4855bcbe0f1e404be204/view
- January 23, 2025: Solicitation, due April 11, 2025 at 5:00 PM EDT. Notice 472ba3f3e4f445ab826cc7bb5304984e. https://sam.gov/workspace/contract/opp/472ba3f3e4f445ab826cc7bb5304984e/view
- February 21, 2025: Solicitation, due April 11, 2025 at 5:00 PM EDT. Notice f50de9c3ce944957a9f90c64555f0e87. https://sam.gov/workspace/contract/opp/f50de9c3ce944957a9f90c64555f0e87/view
- March 14, 2025: Solicitation, due April 24, 2025 at 5:00 PM EDT. Notice bfbfc28293fc48de9911101a74206776. https://sam.gov/workspace/contract/opp/bfbfc28293fc48de9911101a74206776/view
- March 20, 2025: Solicitation, due April 24, 2025 at 5:00 PM EDT. Notice 223414706694467e973cdfcb4041f05a. https://sam.gov/workspace/contract/opp/223414706694467e973cdfcb4041f05a/view

## Points of contact

- RAPID Email Box, RAPID@ARPA-H.gov

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Source: SAM.gov Contract Opportunities bulk extract. Confirm deadlines on SAM.gov before responding. Cite https://abierto.us/opportunities/arpahsol25119.