# Critical Illness Immunological Reprogramming and Control Point Learning Engine (CIRCLE) Innovative Solutions Opening (ISO)

Canonical: https://abierto.us/opportunities/arpahsn26149

- Solicitation number: ARPA-H-SN-26-149
- Notice type: Special notice
- Status: Closed. Deadline was March 9, 2026 at 12:00 PM EDT
- Department: Department of Health and Human Services
- Agency: National Institutes of Health
- Contracting office: Advanced Research Projects Agency for Health (Arpa-H) (75N992)
- NAICS: 541715 Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
- Product or service code: AN13 Health R&D Services; Health Care Services; Experimental Development
- First posted: February 17, 2026
- Last posted: February 17, 2026
- SAM.gov: https://sam.gov/workspace/contract/opp/6db526c327794aeab818768578099e2a/view

## Description

This Special Notice (SN) provides information about the ARPA-H CIRCLE Program Proposers’ Day (PD) on Wednesday, March 11, 2026. ARPA-H published an Innovative Solutions Opening (ISO) solicitation for the CIRCLE program on February 17, 2026. The CIRCLE ISO (ARPA-H-SOL-26-139) is posted on SAM.gov and additional information about the program can be found on the ARPA-H website: https://solutions.arpa-h.gov/circle For additional PD details and registration information see the attached Special Notice (ARPA-H-SN-26-149).

## Publications

- February 17, 2026: Special notice, due March 9, 2026 at 12:00 PM EDT. Notice 4482984f537c4a958918734fe75e0b63. https://sam.gov/workspace/contract/opp/4482984f537c4a958918734fe75e0b63/view
- February 17, 2026: Special notice, due March 9, 2026 at 12:00 PM EDT. Notice 6db526c327794aeab818768578099e2a. https://sam.gov/workspace/contract/opp/6db526c327794aeab818768578099e2a/view

## Points of contact

- CIRCLE ISO Coordinator, CIRCLE@ARPA-H.gov

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Source: SAM.gov Contract Opportunities bulk extract. Confirm deadlines on SAM.gov before responding. Cite https://abierto.us/opportunities/arpahsn26149.