# Request for Information (RFI) on Identifying Basic Research Challenges to Accelerate United States Biotechnology Leadership

Canonical: https://abierto.us/opportunities/89243126rfi0003

- Solicitation number: 892431-26-RFI-0003
- Notice type: Special notice
- Status: Closed. Deadline was October 15, 2026 at 5:00 PM EDT
- Department: Department of Energy
- Contracting office: Department of Energy (n-ENERGYDEPARTMENTOF)
- NAICS: 541714 Research and Development in Biotechnology (except Nanobiotechnology)
- Product or service code: AJ11 General Science And Technology R&D Services; General Science And Technology; Basic Research
- Place of performance: Germantown, Maryland
- County: Montgomery County (FIPS 24031). https://abierto.us/counties/montgomery-county-md-24031
- City: Germantown. https://abierto.us/cities/germantown-md-2432025
- First posted: September 24, 2026
- Last posted: September 24, 2026
- SAM.gov: https://sam.gov/workspace/contract/opp/824d288d826b47609147a5b8db908c09/view

## Description

DOE seeks input on critical basic research challenges, bottlenecks, and missing capabilities needed to transition from descriptive biology to predictive biosystems design. This RFI solicits perspectives on advancing foundational science across biomolecules, cells, microbiomes, and plants to accelerate the production of bio-advantaged fuels, chemicals, and materials. Feedback is specifically requested on fundamental biodesign goals, high-priority biotechnology application areas, and effective collaboration models to help guide BER's strategic priorities, workshop planning, and future funding mechanisms.

## Attachments

- [892431-26-RFI-0003 Attachment.pdf](https://sam.gov/api/prod/opps/v3/opportunities/resources/files/c5b78463ec824cdd87bb59f83276b836/download)

## Publications

- September 24, 2026: Special notice, due October 15, 2026 at 5:00 PM EDT. Notice 824d288d826b47609147a5b8db908c09. https://sam.gov/workspace/contract/opp/824d288d826b47609147a5b8db908c09/view

## Points of contact

- DOE Biotech Input, Biotech.Input@doe.gov

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Source: SAM.gov Contract Opportunities bulk extract. Confirm deadlines on SAM.gov before responding. Cite https://abierto.us/opportunities/89243126rfi0003.