# ADAPT Contract Research Organization - Sources Sought

Canonical: https://abierto.us/opportunities/75n99224rfi103

- Solicitation number: 75N992-24-RFI-103
- Notice type: Sources sought
- Status: Closed. Deadline was September 26, 2024 at 6:00 PM EDT
- Department: Department of Health and Human Services
- Agency: National Institutes of Health
- Contracting office: Advanced Research Projects Agency for Health (Arpa-H) (75N992)
- NAICS: 541715 Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
- Product or service code: AN11 Health R&D Services; Health Care Services; Basic Research
- Place of performance: Bethesda, Maryland
- County: Montgomery County (FIPS 24031). https://abierto.us/counties/montgomery-county-md-24031
- City: Bethesda. https://abierto.us/cities/bethesda-md-2407125
- First posted: August 22, 2024
- Last posted: September 19, 2024
- SAM.gov: https://sam.gov/workspace/contract/opp/00e802d1098c44beb1a090a0a16b061c/view

## Description

The Advanced Research Projects Agency for Health (ARPA-H) Resilient Systems Office seeks to support the procurement of Contract Research Organization (CRO) services for the ADvanced Analysis for Precision cancer Therapy (ADAPT) program. The ADAPT Program aims to revolutionize cancer treatment by developing new adaptive strategies targeting the evolution of cancer. The program will examine a tumor’s behavior as it changes and will then match each patient’s evolving cancer with the best available therapy.

ADAPT will revolutionize cancer care by bringing new science and medicine together to map and target tumor changes that improve survival for patients with metastatic cancer. Key objectives include development of biomarkers of treatment response that can inform and improve patient care decisions, and a clinical trial infrastructure that supports adaptation of therapies iteratively using biomarkers. The ADAPT Program will include linked evolutionary clinical trials undertaken in breast, colon, and lung cancers.

The Contractor will provide Clinical Trial Management, Oversight, Operations, and Research support services to accomplish the mission. The Contractor will provide ARPA-H and its performers with management and research support services, including, but not limited to, systems and tools to assist in the effective oversight and administration of its clinical research program.

In addition, the Contractor will provide adjunct expertise and resources to assure rigorous and efficient clinical study documentation, clinical site monitoring, data and safety monitoring, data management support, and regulatory compliance. This RFI serves to request feedback on the draft tasks within the PWS. Specifically, ARPA-H is looking for feedback, questions, or areas of clarification on tasks within the PWS.

## Publications

- August 22, 2024: Sources sought, due September 5, 2024 at 3:00 PM EDT. Notice 94ace6eed5174a4eac3205d98b3189d6. https://sam.gov/workspace/contract/opp/94ace6eed5174a4eac3205d98b3189d6/view
- September 19, 2024: Sources sought, due September 26, 2024 at 6:00 PM EDT. Notice 00e802d1098c44beb1a090a0a16b061c. https://sam.gov/workspace/contract/opp/00e802d1098c44beb1a090a0a16b061c/view

## Points of contact

- Steven Snyder, steven.snyder@arpa-h.gov
- Elaine Wong, elaine.wong@arpa-h.gov

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Source: SAM.gov Contract Opportunities bulk extract. Confirm deadlines on SAM.gov before responding. Cite https://abierto.us/opportunities/75n99224rfi103.