# NOI - A Non-Invasive Prognostic Biomarker - Circul

Canonical: https://abierto.us/opportunities/75n98027q00007

- Solicitation number: 75N98027Q00007
- Notice type: Combined synopsis and solicitation
- Status: Closed. Deadline was October 23, 2026 at 9:00 AM EDT
- Department: Department of Health and Human Services
- Agency: National Institutes of Health
- Contracting office: National Institutes of Health Olao (75N980)
- NAICS: 541380 Testing Laboratories and Services
- Product or service code: Q301 Reference Laboratory Testing
- Location read from: the notice's description: "T BIRMINGHAM, 701 S 20TH STREET, BIRMINGHAM, AL 35294-0001"
- First posted: October 13, 2026
- Last posted: October 13, 2026
- SAM.gov: https://sam.gov/workspace/contract/opp/66af16818b144456af1ddc0d52fc9378/view

## Description

(i)This is a combined synopsis/solicitation for commercial items prepared in accordancewith the format in FAR Subpart 12.6, as supplemented with additional information includedin this notice. This announcement constitutes the only solicitation; proposals are beingrequested, and a separate written solicitation will not be issued.
(ii)The solicitation number is 75N98027Q00007. This solicitation is issued as a Notice ofIntent (NOI) for a non-competitive combined synopsis/solicitation to award a contract orpurchase order without providing for full and open competition (including brand-name, ifapplicable).
This acquisition is conducted under the authority of FAR 12.603, Streamlined Solicitation for Commercial Products or Commercial Services, and is not expected to exceed the simplified acquisition threshold. Additional authority includes 41 U.S.C. 1901 and FAR 6.302-3(a)(2)(ii).
The National Institutes of Health (NIH), Office of the Director, Office of Acquisitions, intends to negotiate and award a firm-fixed-price purchase order on a non-competitive basis to University of Alabama at Birmingham, 701 S 20th Street, Birmingham, AL 35294-0001-0001, for research support to develop and validate circulating cell-free DNA (cfDNA) as a blood-based biomarker of chlorine-induced acute lung injury, using the Matalon Laboratory's sole-source validated murine chlorine inhalation injury model, established mechanistic expertise, access to its actively enrolling aspiration pneumonitis biorepository (human proxy cohort), existing collaborative infrastructure with the NHLBI Laboratory of Precision Omics, and continuity with peer-reviewed federal funding (NIH R01 HL031197). These capabilities are not available from any other source and are essential to the project's feasibility.
(iii)The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2026-01, effective 03/13/2026.
(iv)The associated NAICS code is 541380, Testing Laboratories and Services, and the small business size standard is $19.0 million. This requirement is not set aside for small business.

## Attachments

- [Sol_75N98027Q00007.pdf](https://sam.gov/api/prod/opps/v3/opportunities/resources/files/817a553017fb49bf9062ccb309d2722b/download)

## Open now in the same industry

23 open in NAICS 541380.

- VACCHCS Pharmacy Certification (36C26127Q0099), due November 2, 2026 at 1:00 PM EST. https://abierto.us/opportunities/36c26127q0099
- Troubleshooting, Calibration and as-needed Remedial Repair of Proof Test Machines (N32253-27-Q-0001), due November 2, 2026 at 4:00 PM EST. https://abierto.us/opportunities/n3225327q0001
- Full Scale Vehicle Crashworthiness Testing and Side Air Bag Out-of-Position Testing for the New Car Assessment Program (NCAP) (693JJ927RQ000049), due November 2, 2026 at 10:00 PM EST. https://abierto.us/opportunities/693jj927rq000049

## Publications

- October 13, 2026: Combined synopsis and solicitation, due October 23, 2026 at 9:00 AM EDT. Notice 66af16818b144456af1ddc0d52fc9378. https://sam.gov/workspace/contract/opp/66af16818b144456af1ddc0d52fc9378/view

## Points of contact

- CAPOBIANCO, NICHOLAS S, nicholas.capobianco@nih.gov, +1 000 000 0000

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Source: SAM.gov Contract Opportunities bulk extract. Confirm deadlines on SAM.gov before responding. Cite https://abierto.us/opportunities/75n98027q00007.
