Title: Dynamic Light Scattering Instrument Upgrade
\n\nSolicitation No.: 75N98026Q01220
\n\nThis is a combined synopsis/solicitation for commercial products or commercial services prepared in accordance with the format in FAR Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; quotations are being requested, and a separate written solicitation will not be issued.
\n\nThe solicitation number is 75N98026Q01220. This solicitation is issued as a Notice of Intent (NOI) for a non-competitive acquisition and is intended to result in the award of a purchase order without providing for full and open competition.
\n\nThis acquisition is conducted under the authority of FAR 12.603, Streamlined Solicitation for Commercial Products or Commercial Services. The statutory authority for this non-competitive acquisition is 41 U.S.C. 1901, as implemented by FAR 6.302-3(a)(2)(ii), as applicable.
\n\nThe National Institutes of Health (NIH), Office of the Director, Office of Acquisitions, intends to negotiate and award a Firm-Fixed-Price Purchase Order on a non-competitive basis to:
\n\nWaters Technologies Corporation
\n34 Maple Street
\nMilford, MA 01757
for a Wyatt Systems DynaPro NanoStar II and associated upgrade/configuration, accessories, standards, installation, training, and technical support.
\n\nDESCRIPTION OF REQUIREMENT
\n\nThe purpose of this acquisition is to replace an aging and failing dynamic light scattering (DLS) instrument currently used by the NIH laboratory. The existing Wyatt DLS instrument is approximately 16 years old and is well beyond its expected service life. In addition, degradation of the instrument's laser has significantly reduced its performance and rendered it unsuitable for many protein samples.
\n\nThe Government requires a replacement system that provides reliable, high-sensitivity dynamic light scattering measurements while maintaining compatibility with the laboratory's existing Wyatt Systems infrastructure, workflows, and applications.
\n\nThe proposed Wyatt Systems DynaPro NanoStar II provides combined Dynamic Light Scattering (DLS) and Static Light Scattering (SLS) capabilities. These complementary measurements provide information regarding particle size and molecular mass and will support characterization of protein complexes and higher-order assemblies relevant to ongoing NIH research involving viral nucleocapsid proteins and other biomolecular systems.
\n\nThe system's broad measurement range, wide temperature range, small-volume sample capability, and rapid, non-destructive measurements are particularly important for research involving limited quantities of protein or samples that are difficult to produce. The ability to perform measurements using small sample volumes will help conserve valuable research materials and facilitate routine sample characterization.
\n\nThe replacement instrument will also support collaborative research projects by providing an accessible and standardized method for screening sample quality before more resource-intensive analyses are undertaken. This capability is expected to improve laboratory efficiency, maximize the use of shared research resources, and enhance the reliability and reproducibility of experimental results.
\n\nFailure to replace the existing instrument would adversely affect mission-critical research activities that rely on DLS characterization and could result in delays to ongoing studies and cascading impacts on collaborating laboratories that depend on access to this capability.
\n\nThe Government requires the complete system configuration, associated standards and consumables, installation, certification, training, and applicable technical support identified below.
\n\nCONTRACT TYPE
\n\nThe Government intends to issue a Firm-Fixed-Price Purchase Order.
\n\nLINE ITEM / PRODUCT REQUIREMENTS
\n\nCLIN 0001 – Wyatt Systems DynaPro NanoStar II
\n\nQuantity: 1 Each
\n\nPart/Model No.: 176850550 1 WYATT Systems
\n\nConfiguration shall include, at a minimum, the following:
\n\nThe offeror shall provide pricing for all required items and associated services, including any applicable tariff charges, shipping, handling, installation, training, certification, and other associated costs.
\n\nAPPLICABLE PROVISIONS AND CLAUSES
\n\nThe solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2026-01, dated March 13, 2026, unless otherwise stated in the resulting purchase order.
\n\nThe associated NAICS code is 334516 – Analytical Laboratory Instrument Manufacturing, and the applicable small business size standard is 1,000 employees.
\n\nThis requirement is not set aside for small business.
\n\nThe provision at FAR 52.212-1, Instructions to Offerors—Commercial Products and Commercial Services, applies to this acquisition.
\n\nThe provision at FAR 52.212-2, Evaluation—Commercial Products and Commercial Services, applies to this acquisition. The Government will evaluate quotations based on technical acceptability, price, delivery, and the offeror's ability to provide the required equipment, proprietary software, accessories, updates, installation, training, warranty, maintenance, and technical support.
\n\nThe Government may make award based on the initial quotation received without conducting discussions.
\n\nA written notice of award or acceptance of an offer, issued to the successful offeror within the time specified in the offer, shall result in a binding contract without further action by either party.
\n\nThe Government reserves the right to accept an offer before the expiration date specified in the offer, whether or not discussions are conducted, unless a written notice of withdrawal is received prior to award.
\n\nOfferors shall include a completed copy of FAR 52.212-3, Offeror Representations and Certifications—Commercial Products and Commercial Services, with their quotation.
\n\nFAR 52.212-4, Contract Terms and Conditions—Commercial Products and Commercial Services, applies to this acquisition.
\n\nFAR 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders—Commercial Products and Commercial Services, applies to this acquisition.
\n\nThe Defense Priorities and Allocations System (DPAS) is not applicable to this requirement.
\n\nSUBMISSION REQUIREMENTS
\n\nResponses shall include sufficient information to demonstrate the respondent's capability to provide the required products and services. Quotations shall include, at a minimum:
\n\nBecause this requirement involves proprietary Wyatt Systems equipment and compatibility with the NIH laboratory's existing Wyatt System, respondents shall provide documentation establishing that the offered products and services are supplied by, authorized by, or otherwise supported by Waters Technologies Corporation/Wyatt Technology and are compatible with the Government's existing Wyatt instrumentation and laboratory workflow.
\n\nResponses shall include, as applicable:
\n\na. Product, catalog, model, and/or part number(s);
\n\nb. Product description;
\n\nc. Documentation demonstrating that the offered items meet the Government's required specifications and compatibility requirements;
\n\nd. Quantity;
\n\ne. Unit and extended pricing;
\n\nf. Shipping, handling, and installation charges;
\n\ng. Delivery timeframe after receipt of order;
\n\nh. Warranty and maintenance terms; and
\n\ni. Documentation establishing authorization to provide the specified proprietary Wyatt products and services if the respondent is not the manufacturer or authorized supplier.
\n\nResponses must also include the offeror's Unique Entity Identifier (UEI), Taxpayer Identification Number (TIN), and business size certification.
\n\nAll offerors must be actively registered in the System for Award Management (SAM) at the time of quotation submission and award.
\n\nRESPONSE DEADLINE
\n\nAll responses must be received no later than September 21, 2026, at 9:00 a.m. Eastern Time.
\n\nResponses shall reference Solicitation No. 75N98026Q01220.
\n\nResponses shall be submitted electronically to:
\n\npatricia.haun@nih.gov
\n\nThe Government intends to evaluate all information received in response to this notice and may make award based on the initial quotation without conducting discussions.
","text":"Title: Dynamic Light Scattering Instrument Upgrade\n\nSolicitation No.: 75N98026Q01220\n\nThis is a combined synopsis/solicitation for commercial products or commercial services prepared in accordance with the format in FAR Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; quotations are being requested, and a separate written solicitation will not be issued.\n\nThe solicitation number is 75N98026Q01220. This solicitation is issued as a Notice of Intent (NOI) for a non-competitive acquisition and is intended to result in the award of a purchase order without providing for full and open competition.\n\nThis acquisition is conducted under the authority of FAR 12.603, Streamlined Solicitation for Commercial Products or Commercial Services. The statutory authority for this non-competitive acquisition is 41 U.S.C. 1901, as implemented by FAR 6.302-3(a)(2)(ii), as applicable.\n\nThe National Institutes of Health (NIH), Office of the Director, Office of Acquisitions, intends to negotiate and award a Firm-Fixed-Price Purchase Order on a non-competitive basis to:\n\nWaters Technologies Corporation\n\n34 Maple Street\n\nMilford, MA 01757\n\nfor a Wyatt Systems DynaPro NanoStar II and associated upgrade/configuration, accessories, standards, installation, training, and technical support.\n\nDESCRIPTION OF REQUIREMENT\n\nThe purpose of this acquisition is to replace an aging and failing dynamic light scattering (DLS) instrument currently used by the NIH laboratory. The existing Wyatt DLS instrument is approximately 16 years old and is well beyond its expected service life. In addition, degradation of the instrument's laser has significantly reduced its performance and rendered it unsuitable for many protein samples.\n\nThe Government requires a replacement system that provides reliable, high-sensitivity dynamic light scattering measurements while maintaining compatibility with the laboratory's existing Wyatt Systems infrastructure, workflows, and applications.\n\nThe proposed Wyatt Systems DynaPro NanoStar II provides combined Dynamic Light Scattering (DLS) and Static Light Scattering (SLS) capabilities. These complementary measurements provide information regarding particle size and molecular mass and will support characterization of protein complexes and higher-order assemblies relevant to ongoing NIH research involving viral nucleocapsid proteins and other biomolecular systems.\n\nThe system's broad measurement range, wide temperature range, small-volume sample capability, and rapid, non-destructive measurements are particularly important for research involving limited quantities of protein or samples that are difficult to produce. The ability to perform measurements using small sample volumes will help conserve valuable research materials and facilitate routine sample characterization.\n\nThe replacement instrument will also support collaborative research projects by providing an accessible and standardized method for screening sample quality before more resource-intensive analyses are undertaken. This capability is expected to improve laboratory efficiency, maximize the use of shared research resources, and enhance the reliability and reproducibility of experimental results.\n\nFailure to replace the existing instrument would adversely affect mission-critical research activities that rely on DLS characterization and could result in delays to ongoing studies and cascading impacts on collaborating laboratories that depend on access to this capability.\n\nThe Government requires the complete system configuration, associated standards and consumables, installation, certification, training, and applicable technical support identified below.\n\nCONTRACT TYPE\n\nThe Government intends to issue a Firm-Fixed-Price Purchase Order.\n\nLINE ITEM / PRODUCT REQUIREMENTS\n\nCLIN 0001 – Wyatt Systems DynaPro NanoStar II\n\nQuantity: 1 Each\n\nPart/Model No.: 176850550 1 WYATT Systems\n\nConfiguration shall include, at a minimum, the following:\n\n• WDN-0200 – Quantity 1\n\nDynaPro NanoStar II, 45 µL, Active USB.\n\n• 900113 – Quantity 2\n\n1 mL ampule of Bovine Serum Albumin with lot certification. Concentration: 2 mg/mL. Provides molar mass validation and normalization for DAWN, miniDAWN, and microDAWN systems using an aqueous mobile phase and provides molar mass and size validation for DynaPro NanoStar, DynaPro Plate Reader, and related Wyatt instrumentation.\n\n• 900174 – Quantity 1\n\n15 mL vial of aqueous suspension of polystyrene latex spheres for batch size and concentration validation for NanoStar, NanoStar II, ZetaStar, or Plate Reader. Certificates of Analysis and Safety Data Sheets are available through the manufacturer's documentation portal.\n\n• 900175 – Quantity 1\n\n15 mL vial of aqueous suspension of polystyrene latex spheres for batch size and concentration validation for NanoStar, NanoStar II, ZetaStar, or Plate Reader.\n\n• 900107 – Quantity 1\n\nInstrument Installation Kit.\n\n• 725000561 – Quantity 1\n\nEthernet Switch, 10/100/1000Base-T, 8-Port.\n\n• 900510 – Quantity 1\n\nDYNAMICS 8 with DYNAMICS Touch.\n\n• WZDMC – Quantity 1\n\nPackage of 30 disposable cuvettes with 3 reusable caps for NanoStar II and ZetaStar. Cuvettes require a minimum sample volume of approximately 4 µL and are constructed of cyclic olefin copolymer (COC).\n\n• 741000536 – Quantity 1\n\nWyatt System Installation Certification.\n\n• Y-LSU2G – Quantity 1\n\nTraining, LSU – 2 Days.\n\n• 740007188 – Quantity 1\n\nTAW DynaPro NS/NS with Online DLS.\n\nThe offeror shall provide pricing for all required items and associated services, including any applicable tariff charges, shipping, handling, installation, training, certification, and other associated costs.\n\nAPPLICABLE PROVISIONS AND CLAUSES\n\nThe solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2026-01, dated March 13, 2026, unless otherwise stated in the resulting purchase order.\n\nThe associated NAICS code is 334516 – Analytical Laboratory Instrument Manufacturing, and the applicable small business size standard is 1,000 employees.\n\nThis requirement is not set aside for small business.\n\nThe provision at FAR 52.212-1, Instructions to Offerors—Commercial Products and Commercial Services, applies to this acquisition.\n\nThe provision at FAR 52.212-2, Evaluation—Commercial Products and Commercial Services, applies to this acquisition. The Government will evaluate quotations based on technical acceptability, price, delivery, and the offeror's ability to provide the required equipment, proprietary software, accessories, updates, installation, training, warranty, maintenance, and technical support.\n\nThe Government may make award based on the initial quotation received without conducting discussions.\n\nA written notice of award or acceptance of an offer, issued to the successful offeror within the time specified in the offer, shall result in a binding contract without further action by either party.\n\nThe Government reserves the right to accept an offer before the expiration date specified in the offer, whether or not discussions are conducted, unless a written notice of withdrawal is received prior to award.\n\nOfferors shall include a completed copy of FAR 52.212-3, Offeror Representations and Certifications—Commercial Products and Commercial Services, with their quotation.\n\nFAR 52.212-4, Contract Terms and Conditions—Commercial Products and Commercial Services, applies to this acquisition.\n\nFAR 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders—Commercial Products and Commercial Services, applies to this acquisition.\n\nThe Defense Priorities and Allocations System (DPAS) is not applicable to this requirement.\n\nSUBMISSION REQUIREMENTS\n\nResponses shall include sufficient information to demonstrate the respondent's capability to provide the required products and services. Quotations shall include, at a minimum:\n\n• Unit price;\n\n• List price, if applicable;\n\n• Shipping and handling costs;\n\n• Delivery timeframe after award;\n\n• Delivery terms;\n\n• Prompt payment discount terms;\n\n• F.O.B. point (destination or origin);\n\n• Product, model, catalog, and/or part numbers;\n\n• Product descriptions;\n\n• Warranty and maintenance information; and\n\n• Any other information relevant to the Government's evaluation.\n\nBecause this requirement involves proprietary Wyatt Systems equipment and compatibility with the NIH laboratory's existing Wyatt System, respondents shall provide documentation establishing that the offered products and services are supplied by, authorized by, or otherwise supported by Waters Technologies Corporation/Wyatt Technology and are compatible with the Government's existing Wyatt instrumentation and laboratory workflow.\n\nResponses shall include, as applicable:\n\na. Product, catalog, model, and/or part number(s);\n\nb. Product description;\n\nc. Documentation demonstrating that the offered items meet the Government's required specifications and compatibility requirements;\n\nd. Quantity;\n\ne. Unit and extended pricing;\n\nf. Shipping, handling, and installation charges;\n\ng. Delivery timeframe after receipt of order;\n\nh. Warranty and maintenance terms; and\n\ni. Documentation establishing authorization to provide the specified proprietary Wyatt products and services if the respondent is not the manufacturer or authorized supplier.\n\nResponses must also include the offeror's Unique Entity Identifier (UEI), Taxpayer Identification Number (TIN), and business size certification.\n\nAll offerors must be actively registered in the System for Award Management (SAM) at the time of quotation submission and award.\n\nRESPONSE DEADLINE\n\nAll responses must be received no later than September 21, 2026, at 9:00 a.m. Eastern Time.\n\nResponses shall reference Solicitation No. 75N98026Q01220.\n\nResponses shall be submitted electronically to:\n\npatricia.haun@nih.gov\n\nThe Government intends to evaluate all information received in response to this notice and may make award based on the initial quotation without conducting discussions.","origin":"detail"},"notice_type":{"code":"k","label":"Combined Synopsis/Solicitation"},"schema_version":1,"solicitation_number":"75N98026Q01220","place_of_performance":{"zip":"20892","city":{"code":"7125","name":"Bethesda"},"state":{"code":"MD","name":"Maryland"},"country":{"code":"USA","name":"UNITED STATES"}},"product_service_code":"6640"}],"due_at":"2026-09-21T13:00:00Z","due_date":"2026-09-21","closes_at":"2026-09-21T13:00:00Z","awardable":true,"dept_key":"d-075","dept_name":"HEALTH AND HUMAN SERVICES, DEPARTMENT OF","sub_key":"s-7529","sub_name":"NATIONAL INSTITUTES OF HEALTH","office_key":"o-75N980","office_name":"NATIONAL INSTITUTES OF HEALTH OLAO","state":"MD","country":"USA","winner_key":null,"amount":null,"linked_awards":0,"cancelled":false,"archived":false,"updated_at":"2026-09-16T07:50:43.959643Z","principal_notice_id":"36fe55a93289425da1d94da32e3b5f68","description":{"text":"Title: Dynamic Light Scattering Instrument Upgrade\n\nSolicitation No.: 75N98026Q01220\n\nThis is a combined synopsis/solicitation for commercial products or commercial services prepared in accordance with the format in FAR Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; quotations are being requested, and a separate written solicitation will not be issued.\n\nThe solicitation number is 75N98026Q01220. This solicitation is issued as a Notice of Intent (NOI) for a non-competitive acquisition and is intended to result in the award of a purchase order without providing for full and open competition.\n\nThis acquisition is conducted under the authority of FAR 12.603, Streamlined Solicitation for Commercial Products or Commercial Services. The statutory authority for this non-competitive acquisition is 41 U.S.C. 1901, as implemented by FAR 6.302-3(a)(2)(ii), as applicable.\n\nThe National Institutes of Health (NIH), Office of the Director, Office of Acquisitions, intends to negotiate and award a Firm-Fixed-Price Purchase Order on a non-competitive basis to:\n\nWaters Technologies Corporation\n\n34 Maple Street\n\nMilford, MA 01757\n\nfor a Wyatt Systems DynaPro NanoStar II and associated upgrade/configuration, accessories, standards, installation, training, and technical support.\n\nDESCRIPTION OF REQUIREMENT\n\nThe purpose of this acquisition is to replace an aging and failing dynamic light scattering (DLS) instrument currently used by the NIH laboratory. The existing Wyatt DLS instrument is approximately 16 years old and is well beyond its expected service life. In addition, degradation of the instrument's laser has significantly reduced its performance and rendered it unsuitable for many protein samples.\n\nThe Government requires a replacement system that provides reliable, high-sensitivity dynamic light scattering measurements while maintaining compatibility with the laboratory's existing Wyatt Systems infrastructure, workflows, and applications.\n\nThe proposed Wyatt Systems DynaPro NanoStar II provides combined Dynamic Light Scattering (DLS) and Static Light Scattering (SLS) capabilities. These complementary measurements provide information regarding particle size and molecular mass and will support characterization of protein complexes and higher-order assemblies relevant to ongoing NIH research involving viral nucleocapsid proteins and other biomolecular systems.\n\nThe system's broad measurement range, wide temperature range, small-volume sample capability, and rapid, non-destructive measurements are particularly important for research involving limited quantities of protein or samples that are difficult to produce. The ability to perform measurements using small sample volumes will help conserve valuable research materials and facilitate routine sample characterization.\n\nThe replacement instrument will also support collaborative research projects by providing an accessible and standardized method for screening sample quality before more resource-intensive analyses are undertaken. This capability is expected to improve laboratory efficiency, maximize the use of shared research resources, and enhance the reliability and reproducibility of experimental results.\n\nFailure to replace the existing instrument would adversely affect mission-critical research activities that rely on DLS characterization and could result in delays to ongoing studies and cascading impacts on collaborating laboratories that depend on access to this capability.\n\nThe Government requires the complete system configuration, associated standards and consumables, installation, certification, training, and applicable technical support identified below.\n\nCONTRACT TYPE\n\nThe Government intends to issue a Firm-Fixed-Price Purchase Order.\n\nLINE ITEM / PRODUCT REQUIREMENTS\n\nCLIN 0001 – Wyatt Systems DynaPro NanoStar II\n\nQuantity: 1 Each\n\nPart/Model No.: 176850550 1 WYATT Systems\n\nConfiguration shall include, at a minimum, the following:\n\n• WDN-0200 – Quantity 1\n\nDynaPro NanoStar II, 45 µL, Active USB.\n\n• 900113 – Quantity 2\n\n1 mL ampule of Bovine Serum Albumin with lot certification. Concentration: 2 mg/mL. Provides molar mass validation and normalization for DAWN, miniDAWN, and microDAWN systems using an aqueous mobile phase and provides molar mass and size validation for DynaPro NanoStar, DynaPro Plate Reader, and related Wyatt instrumentation.\n\n• 900174 – Quantity 1\n\n15 mL vial of aqueous suspension of polystyrene latex spheres for batch size and concentration validation for NanoStar, NanoStar II, ZetaStar, or Plate Reader. Certificates of Analysis and Safety Data Sheets are available through the manufacturer's documentation portal.\n\n• 900175 – Quantity 1\n\n15 mL vial of aqueous suspension of polystyrene latex spheres for batch size and concentration validation for NanoStar, NanoStar II, ZetaStar, or Plate Reader.\n\n• 900107 – Quantity 1\n\nInstrument Installation Kit.\n\n• 725000561 – Quantity 1\n\nEthernet Switch, 10/100/1000Base-T, 8-Port.\n\n• 900510 – Quantity 1\n\nDYNAMICS 8 with DYNAMICS Touch.\n\n• WZDMC – Quantity 1\n\nPackage of 30 disposable cuvettes with 3 reusable caps for NanoStar II and ZetaStar. Cuvettes require a minimum sample volume of approximately 4 µL and are constructed of cyclic olefin copolymer (COC).\n\n• 741000536 – Quantity 1\n\nWyatt System Installation Certification.\n\n• Y-LSU2G – Quantity 1\n\nTraining, LSU – 2 Days.\n\n• 740007188 – Quantity 1\n\nTAW DynaPro NS/NS with Online DLS.\n\nThe offeror shall provide pricing for all required items and associated services, including any applicable tariff charges, shipping, handling, installation, training, certification, and other associated costs.\n\nAPPLICABLE PROVISIONS AND CLAUSES\n\nThe solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2026-01, dated March 13, 2026, unless otherwise stated in the resulting purchase order.\n\nThe associated NAICS code is 334516 – Analytical Laboratory Instrument Manufacturing, and the applicable small business size standard is 1,000 employees.\n\nThis requirement is not set aside for small business.\n\nThe provision at FAR 52.212-1, Instructions to Offerors—Commercial Products and Commercial Services, applies to this acquisition.\n\nThe provision at FAR 52.212-2, Evaluation—Commercial Products and Commercial Services, applies to this acquisition. The Government will evaluate quotations based on technical acceptability, price, delivery, and the offeror's ability to provide the required equipment, proprietary software, accessories, updates, installation, training, warranty, maintenance, and technical support.\n\nThe Government may make award based on the initial quotation received without conducting discussions.\n\nA written notice of award or acceptance of an offer, issued to the successful offeror within the time specified in the offer, shall result in a binding contract without further action by either party.\n\nThe Government reserves the right to accept an offer before the expiration date specified in the offer, whether or not discussions are conducted, unless a written notice of withdrawal is received prior to award.\n\nOfferors shall include a completed copy of FAR 52.212-3, Offeror Representations and Certifications—Commercial Products and Commercial Services, with their quotation.\n\nFAR 52.212-4, Contract Terms and Conditions—Commercial Products and Commercial Services, applies to this acquisition.\n\nFAR 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders—Commercial Products and Commercial Services, applies to this acquisition.\n\nThe Defense Priorities and Allocations System (DPAS) is not applicable to this requirement.\n\nSUBMISSION REQUIREMENTS\n\nResponses shall include sufficient information to demonstrate the respondent's capability to provide the required products and services. Quotations shall include, at a minimum:\n\n• Unit price;\n\n• List price, if applicable;\n\n• Shipping and handling costs;\n\n• Delivery timeframe after award;\n\n• Delivery terms;\n\n• Prompt payment discount terms;\n\n• F.O.B. point (destination or origin);\n\n• Product, model, catalog, and/or part numbers;\n\n• Product descriptions;\n\n• Warranty and maintenance information; and\n\n• Any other information relevant to the Government's evaluation.\n\nBecause this requirement involves proprietary Wyatt Systems equipment and compatibility with the NIH laboratory's existing Wyatt System, respondents shall provide documentation establishing that the offered products and services are supplied by, authorized by, or otherwise supported by Waters Technologies Corporation/Wyatt Technology and are compatible with the Government's existing Wyatt instrumentation and laboratory workflow.\n\nResponses shall include, as applicable:\n\na. Product, catalog, model, and/or part number(s);\n\nb. Product description;\n\nc. Documentation demonstrating that the offered items meet the Government's required specifications and compatibility requirements;\n\nd. Quantity;\n\ne. Unit and extended pricing;\n\nf. Shipping, handling, and installation charges;\n\ng. Delivery timeframe after receipt of order;\n\nh. Warranty and maintenance terms; and\n\ni. Documentation establishing authorization to provide the specified proprietary Wyatt products and services if the respondent is not the manufacturer or authorized supplier.\n\nResponses must also include the offeror's Unique Entity Identifier (UEI), Taxpayer Identification Number (TIN), and business size certification.\n\nAll offerors must be actively registered in the System for Award Management (SAM) at the time of quotation submission and award.\n\nRESPONSE DEADLINE\n\nAll responses must be received no later than September 21, 2026, at 9:00 a.m. Eastern Time.\n\nResponses shall reference Solicitation No. 75N98026Q01220.\n\nResponses shall be submitted electronically to:\n\npatricia.haun@nih.gov\n\nThe Government intends to evaluate all information received in response to this notice and may make award based on the initial quotation without conducting discussions.","html":"Title: Dynamic Light Scattering Instrument Upgrade
\n\nSolicitation No.: 75N98026Q01220
\n\nThis is a combined synopsis/solicitation for commercial products or commercial services prepared in accordance with the format in FAR Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; quotations are being requested, and a separate written solicitation will not be issued.
\n\nThe solicitation number is 75N98026Q01220. This solicitation is issued as a Notice of Intent (NOI) for a non-competitive acquisition and is intended to result in the award of a purchase order without providing for full and open competition.
\n\nThis acquisition is conducted under the authority of FAR 12.603, Streamlined Solicitation for Commercial Products or Commercial Services. The statutory authority for this non-competitive acquisition is 41 U.S.C. 1901, as implemented by FAR 6.302-3(a)(2)(ii), as applicable.
\n\nThe National Institutes of Health (NIH), Office of the Director, Office of Acquisitions, intends to negotiate and award a Firm-Fixed-Price Purchase Order on a non-competitive basis to:
\n\nWaters Technologies Corporation
\n34 Maple Street
\nMilford, MA 01757
for a Wyatt Systems DynaPro NanoStar II and associated upgrade/configuration, accessories, standards, installation, training, and technical support.
\n\nDESCRIPTION OF REQUIREMENT
\n\nThe purpose of this acquisition is to replace an aging and failing dynamic light scattering (DLS) instrument currently used by the NIH laboratory. The existing Wyatt DLS instrument is approximately 16 years old and is well beyond its expected service life. In addition, degradation of the instrument's laser has significantly reduced its performance and rendered it unsuitable for many protein samples.
\n\nThe Government requires a replacement system that provides reliable, high-sensitivity dynamic light scattering measurements while maintaining compatibility with the laboratory's existing Wyatt Systems infrastructure, workflows, and applications.
\n\nThe proposed Wyatt Systems DynaPro NanoStar II provides combined Dynamic Light Scattering (DLS) and Static Light Scattering (SLS) capabilities. These complementary measurements provide information regarding particle size and molecular mass and will support characterization of protein complexes and higher-order assemblies relevant to ongoing NIH research involving viral nucleocapsid proteins and other biomolecular systems.
\n\nThe system's broad measurement range, wide temperature range, small-volume sample capability, and rapid, non-destructive measurements are particularly important for research involving limited quantities of protein or samples that are difficult to produce. The ability to perform measurements using small sample volumes will help conserve valuable research materials and facilitate routine sample characterization.
\n\nThe replacement instrument will also support collaborative research projects by providing an accessible and standardized method for screening sample quality before more resource-intensive analyses are undertaken. This capability is expected to improve laboratory efficiency, maximize the use of shared research resources, and enhance the reliability and reproducibility of experimental results.
\n\nFailure to replace the existing instrument would adversely affect mission-critical research activities that rely on DLS characterization and could result in delays to ongoing studies and cascading impacts on collaborating laboratories that depend on access to this capability.
\n\nThe Government requires the complete system configuration, associated standards and consumables, installation, certification, training, and applicable technical support identified below.
\n\nCONTRACT TYPE
\n\nThe Government intends to issue a Firm-Fixed-Price Purchase Order.
\n\nLINE ITEM / PRODUCT REQUIREMENTS
\n\nCLIN 0001 – Wyatt Systems DynaPro NanoStar II
\n\nQuantity: 1 Each
\n\nPart/Model No.: 176850550 1 WYATT Systems
\n\nConfiguration shall include, at a minimum, the following:
\n\nThe offeror shall provide pricing for all required items and associated services, including any applicable tariff charges, shipping, handling, installation, training, certification, and other associated costs.
\n\nAPPLICABLE PROVISIONS AND CLAUSES
\n\nThe solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2026-01, dated March 13, 2026, unless otherwise stated in the resulting purchase order.
\n\nThe associated NAICS code is 334516 – Analytical Laboratory Instrument Manufacturing, and the applicable small business size standard is 1,000 employees.
\n\nThis requirement is not set aside for small business.
\n\nThe provision at FAR 52.212-1, Instructions to Offerors—Commercial Products and Commercial Services, applies to this acquisition.
\n\nThe provision at FAR 52.212-2, Evaluation—Commercial Products and Commercial Services, applies to this acquisition. The Government will evaluate quotations based on technical acceptability, price, delivery, and the offeror's ability to provide the required equipment, proprietary software, accessories, updates, installation, training, warranty, maintenance, and technical support.
\n\nThe Government may make award based on the initial quotation received without conducting discussions.
\n\nA written notice of award or acceptance of an offer, issued to the successful offeror within the time specified in the offer, shall result in a binding contract without further action by either party.
\n\nThe Government reserves the right to accept an offer before the expiration date specified in the offer, whether or not discussions are conducted, unless a written notice of withdrawal is received prior to award.
\n\nOfferors shall include a completed copy of FAR 52.212-3, Offeror Representations and Certifications—Commercial Products and Commercial Services, with their quotation.
\n\nFAR 52.212-4, Contract Terms and Conditions—Commercial Products and Commercial Services, applies to this acquisition.
\n\nFAR 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders—Commercial Products and Commercial Services, applies to this acquisition.
\n\nThe Defense Priorities and Allocations System (DPAS) is not applicable to this requirement.
\n\nSUBMISSION REQUIREMENTS
\n\nResponses shall include sufficient information to demonstrate the respondent's capability to provide the required products and services. Quotations shall include, at a minimum:
\n\nBecause this requirement involves proprietary Wyatt Systems equipment and compatibility with the NIH laboratory's existing Wyatt System, respondents shall provide documentation establishing that the offered products and services are supplied by, authorized by, or otherwise supported by Waters Technologies Corporation/Wyatt Technology and are compatible with the Government's existing Wyatt instrumentation and laboratory workflow.
\n\nResponses shall include, as applicable:
\n\na. Product, catalog, model, and/or part number(s);
\n\nb. Product description;
\n\nc. Documentation demonstrating that the offered items meet the Government's required specifications and compatibility requirements;
\n\nd. Quantity;
\n\ne. Unit and extended pricing;
\n\nf. Shipping, handling, and installation charges;
\n\ng. Delivery timeframe after receipt of order;
\n\nh. Warranty and maintenance terms; and
\n\ni. Documentation establishing authorization to provide the specified proprietary Wyatt products and services if the respondent is not the manufacturer or authorized supplier.
\n\nResponses must also include the offeror's Unique Entity Identifier (UEI), Taxpayer Identification Number (TIN), and business size certification.
\n\nAll offerors must be actively registered in the System for Award Management (SAM) at the time of quotation submission and award.
\n\nRESPONSE DEADLINE
\n\nAll responses must be received no later than September 21, 2026, at 9:00 a.m. Eastern Time.
\n\nResponses shall reference Solicitation No. 75N98026Q01220.
\n\nResponses shall be submitted electronically to:
\n\npatricia.haun@nih.gov
\n\nThe Government intends to evaluate all information received in response to this notice and may make award based on the initial quotation without conducting discussions.
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