# Title: Cellink BIO X Advanced Multi-Material 3D Bioprinting System for Cancer Biology and Organoid Research

Canonical: https://abierto.us/opportunities/75n98026q01018cellinknci09639

- Solicitation number: 75N98026Q01018CELLINKNCI09639
- Notice type: Presolicitation
- Status: Closed. Deadline was August 15, 2026 at 9:00 AM EDT
- Department: Department of Health and Human Services
- Agency: National Institutes of Health
- Contracting office: National Institutes of Health Olao (75N980)
- NAICS: 541714 Research and Development in Biotechnology (except Nanobiotechnology)
- Product or service code: 6640 Laboratory Equipment and Supplies
- Place of performance: Bethesda, Maryland
- County: Montgomery County (FIPS 24031). https://abierto.us/counties/montgomery-county-md-24031
- City: Bethesda. https://abierto.us/cities/bethesda-md-2407125
- First posted: August 15, 2026
- Last posted: August 15, 2026
- SAM.gov: https://sam.gov/workspace/contract/opp/5977b75460a2459693588d1d06748226/view

## Description

THE LABORATORY INVESTIGATES MECHANISMS FO TUMORS INITIATIONS PROGRESSION AND THERAPEUTIC RESPONSE USING ADVANCED THREE DIMENSIONAL(3d) CULTURE SYSTEMS ORGANID MODELS AND ENGINEERED TISSUE MICRONMENTS . CURRENT RESEARCH FOCUESES ON UNDERSTANDING INTERACTIONS BETWEEN TUMORS CELLS AND THERI SURROUNDING STROMAL AND EXTRACULLULAR MATRIX ENVIRONMENTS THAT INFLUENCE CANCER DEVELOPMENT AND TREATMENT RESPONSE.

EXISTING LABORATORY METHODS FOR GENERATING 3D TISSUEMODELS RELYON MANUAL PREPRATION TECHNIQUES THAT INTRODUCE VARIABILITY IN CONSTRUCT GEOMETRY, CELL DISTRUBUTION, AND EXTRACELLULAR MATRIX COMPOSITION. THESE LIMITATIONS REDUCE EXPERIMENTAL REPRODUCIBILITY AND RESTRICT THE COMPLEXITY OF TISSUE MODELS THAT CAN BE GENERATED.

TO SUPPORT ONGOING NIH-FUNDED RESEARCH, THEMUTHUSWAMY LABORATORY REQUIRES A HIGH-PRECISION 3DE BIOPRINTING PLATFORM CAPABLE OF REPRODUCIBLY FABRICATING MULTICELLULAR TISSUE CONSTRUCTS USING A VARIETY OF BIOMARKS AND BIOMATERIALS. THE SYSTEM MUST INTEGRATE WITH EXISTING CELL CULTURE, MICROSCOPY, AND DOWNSTREAM MOLECULAR ANALYSIS WORKFLOWS WHILE ENABLING STANDARDIZED PRODUCTION OF PHYSIOLOGICALLY RELEVENT INVITRO MODELS.

## Publications

- August 15, 2026: Presolicitation, due August 15, 2026 at 9:00 AM EDT. Notice 5977b75460a2459693588d1d06748226. https://sam.gov/workspace/contract/opp/5977b75460a2459693588d1d06748226/view

## Points of contact

- Vishnuvajjala Hanumanth Rao, vishnuh@mail.nih.gov

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Source: SAM.gov Contract Opportunities bulk extract. Confirm deadlines on SAM.gov before responding. Cite https://abierto.us/opportunities/75n98026q01018cellinknci09639.