# DIABETES MOLECULAR GENETICS SECTION CELL SORTER

Canonical: https://abierto.us/opportunities/75n98026q00841bdbio

- Solicitation number: 75N98026Q00841BDBIO
- Notice type: Presolicitation
- Status: Closed. Deadline was July 30, 2026 at 9:00 AM EDT
- Department: Department of Health and Human Services
- Agency: National Institutes of Health
- Contracting office: National Institutes of Health Olao (75N980)
- NAICS: 334516 Analytical Laboratory Instrument Manufacturing
- Product or service code: 6505 Drugs and Biologicals
- Place of performance: Bethesda, Maryland
- First posted: July 21, 2026
- Last posted: July 21, 2026
- SAM.gov: https://sam.gov/workspace/contract/opp/afad10912be74bbebb338a8517653829/view

## Description

THE DIABETES MILECULAR GENETICS SECTION OF THE PHOENIX EPIDEMOLOGY AND CLINICAL RESEARCH BRANCH AT THE NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES STUDIES STEM CELL DERIVED PANCREATIC ISLET ORGANOIDS COMPOSE OF MULTIPLE CELL. MANY EXPERIMENTS REQUIRE ISOLATION AND ANALYSIS OF SPECIFIC CELL POPULATIONS BECAUSE MIXED CELL POPULATIONS CAN PRODUCE UNCLEAR OR MISLEADING RESULTS. ALTHOUGH SINGLE-CELL SEQUENCING CAN IDENTIFY INDIVIDUAL CELL TYPES, IT IS COSTLY AND NOT PRACTICAL FOR ROUTING USES.

AMORE EFFICIENT APPROACH IS TO SEPARATE CELLS BASED ON PROTEINS EXPRESSED ON THE CELL SURFACE. THE BD FACSMELODY CELL SORTGER WITH THREE LASERS AND NINE-COLOR CAPABILITY WILL ALLOW RESEARCHERS TO ANALYZE AND ISOLATE SPECIFIC CELL POPULATIONS FROM ORGANOIDS USING FLUORESCENT MARKERS. THIS CAPABILITY WITH SUPPORT DOWNSTREAM EXPERIMENTS FOCUSED ON CELL IDENTITY, MATURATION, AND RESPOSE TO EXPERIMENTAL CONDITIONS WHILE REDUCING RELIANCE ON MORE EXPENSIVE SINGLE-CELL SEQUENCING METHODS

## Publications

- July 21, 2026: Presolicitation, due July 30, 2026 at 9:00 AM EDT. Notice afad10912be74bbebb338a8517653829. https://sam.gov/workspace/contract/opp/afad10912be74bbebb338a8517653829/view

## Points of contact

- Vishnuvajjala Hanumanth Rao, vishnuh@mail.nih.gov

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Source: SAM.gov Contract Opportunities bulk extract. Confirm deadlines on SAM.gov before responding. Cite https://abierto.us/opportunities/75n98026q00841bdbio.