# OpenEye Software Annual Licenses

Canonical: https://abierto.us/opportunities/75n98026q00472

- Solicitation number: 75N98026Q00472
- Notice type: Combined synopsis and solicitation
- Status: Awarded to Openeye Scientific Software, Inc.
- Department: Department of Health and Human Services
- Agency: Office of the Assistant Secretary for Financial Resources
- Contracting office: Omas Strategic Buying Center - Information Technology (7571TE)
- NAICS: 541511 Custom Computer Programming Services
- Product or service code: 7A21 Business Application off-the-shelf software delivered by perpetual license, which also encompasses enterprise level software enabling mission capability and business operational support.
- Set-aside: Total small business set-aside
- Place of performance: Maryland
- County: Montgomery County (FIPS 24031). https://abierto.us/counties/montgomery-county-md-24031
- City: Bethesda. https://abierto.us/cities/bethesda-md-2407125
- First posted: May 29, 2026
- Last posted: June 5, 2026
- SAM.gov: https://sam.gov/workspace/contract/opp/79ce75fd25d94a4eb223b30ceeb3a05f/view

## Description

This requirement supports ongoing translational science and drug discovery activities conducted by Early Translation Branch (ETB), Chemical Genomics Branch (CGB), Informatics Core (IFX), and collaborating NCATS researchers. The requirement is for the OpenEye Non-Profit Package, including BROOD, EON, FILTER, OEChem TK, OEDocking, OMEGA, OMEGA DB, pKa Prospector, QUACPAC, ROCS, SITEHOPPER, SPRUCE, SZMAP, SZYBKI, and VIDA.

The software supports: • comparison of synthesized small molecules using NCATS-generated biological data • molecular modeling and virtual screening • structure-activity relationship analysis • molecular docking, conformer generation, and lead optimization • qHTS data mining and related cheminformatics workflows • continuity of in-house tools built on the OpenEye platform Salient characteristics: • Must provide reinstatement of the existing OpenEye software subscription environment currently used by NCATS • Must support molecular modeling, virtual screening, and structure-based and ligand-based computational chemistry workflows • Must support comparison of chemical structures by shape, electrostatics, and related molecular properties • Must support conformer generation, molecular preparation, docking, visualization, and analysis • Must support structure-activity relationship analysis and compound prioritization for follow-on testing • Must maintain compatibility with existing NCATS workflows and internally developed tools that rely on the OpenEye platform • Must support continuity of scientific operations with minimal disruption following lapse of coverage • Must include vendor licensing, updates, and support associated with the proprietary OpenEye package

## Award on USAspending

- Recipient: Openeye Scientific Software, Inc. (UEI NUUHK6HHEW91)
- Contract: 75N98026P00806, purchase order
- Obligated: $53,760.00
- Competition: Competed Under SAP, 1 offers received
- Link: solicitation number 75N98026Q00472 equals the FPDS solicitation identifier; awarding office not confirmed (medium confidence)
- Record: https://www.usaspending.gov/award/CONT_AWD_75N98026P00806_7529_-NONE-_-NONE-/


## Publications

- May 29, 2026: Combined synopsis and solicitation, due June 5, 2026 at 2:30 PM EDT. Notice 4f87a96ff83a4d5082daa5271ed03161. https://sam.gov/workspace/contract/opp/4f87a96ff83a4d5082daa5271ed03161/view
- June 5, 2026: Combined synopsis and solicitation, due June 5, 2026 at 2:30 PM EDT. Notice 79ce75fd25d94a4eb223b30ceeb3a05f. https://sam.gov/workspace/contract/opp/79ce75fd25d94a4eb223b30ceeb3a05f/view

## Points of contact

- Damian Hurge, Damian.Hurge@HHS.gov, 301-348-3519

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Source: SAM.gov Contract Opportunities bulk extract and USAspending.gov award data. Confirm deadlines on SAM.gov before responding. Cite https://abierto.us/opportunities/75n98026q00472.