# Toxicity evaluation of YC1 in hSULT1A1 and mSULT1A1 mice

Canonical: https://abierto.us/opportunities/75n95025q00237

- Solicitation number: 75N95025Q00237
- Notice type: Presolicitation
- Status: Awarded to Gempharmatech LLC
- Department: Department of Health and Human Services
- Agency: National Institutes of Health
- Contracting office: National Institutes of Health Nida (75N950)
- NAICS: 541380 Testing Laboratories and Services
- Product or service code: B504 Chemical/Biological Studies and Analysis
- Place of performance: Rockville, Maryland
- County: Montgomery County (FIPS 24031). https://abierto.us/counties/montgomery-county-md-24031
- City: Rockville. https://abierto.us/cities/rockville-md-2467675
- First posted: August 12, 2025
- Last posted: August 12, 2025
- SAM.gov: https://sam.gov/workspace/contract/opp/9297051a89bc4a30944a0f0465525a52/view

## Description

NCATS seeks to determine if YC1 which works with a unique mechanism of cytotoxicity towards cancer cells that express SULT1A1. In doing so, NCATS shall establish the therapeutic window for YC1. To that end NCATS requires head-to-head comparison on YC1 in mice that have humanized SULT1A1 (custom mice available at GemPharmaTech) and with mouse SULT1A1 (wild type).

## Award on USAspending

- Recipient: Gempharmatech LLC (UEI H42SCKKGRTU3)
- Contract: 75N95025P00413, purchase order
- Obligated: $58,936.00
- Competition: Not Competed Under SAP, 1 offers received
- Link: solicitation number 75N95025Q00237 equals the FPDS solicitation identifier; same awarding office 75N950 (high confidence)
- Record: https://www.usaspending.gov/award/CONT_AWD_75N95025P00413_7529_-NONE-_-NONE-/


## Publications

- August 12, 2025: Presolicitation, due August 18, 2025 at 12:00 PM EDT. Notice 9297051a89bc4a30944a0f0465525a52. https://sam.gov/workspace/contract/opp/9297051a89bc4a30944a0f0465525a52/view

## Points of contact

- Andrew Varley, andrew.varley@nih.gov, 3018275851
- Joshua T. Lazarus, Josh.Lazarus@nih.gov, 3018276923

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Source: SAM.gov Contract Opportunities bulk extract and USAspending.gov award data. Confirm deadlines on SAM.gov before responding. Cite https://abierto.us/opportunities/75n95025q00237.