# Self-Administration System

Canonical: https://abierto.us/opportunities/75n95025q00203

- Solicitation number: 75N95025Q00203
- Notice type: Sources sought
- Status: Closed. Deadline was July 17, 2025 at 3:00 PM EDT
- Department: Department of Health and Human Services
- Agency: National Institutes of Health
- Contracting office: National Institutes of Health Nida (75N950)
- NAICS: 334516 Analytical Laboratory Instrument Manufacturing
- Product or service code: 6640 Laboratory Equipment and Supplies
- First posted: July 7, 2025
- Last posted: July 7, 2025
- SAM.gov: https://sam.gov/workspace/contract/opp/3f6e50ab3df24ce08355e70538b39f43/view

## Description

NRB previously identified that change in brain regions using the non-invasive imaging technique called functional magnetic resonance imaging (fMRI) associated with addiction vulnerability. This vulnerability can be measured by drug-taking behavior despite foot shock in rats. Early social experiences, including peer interactions, are critical for brain development and behavioral regulation. Disruptions in these experiences have been linked to increased risk of substance use disorders.

However, it is unclear how social experiences affect vulnerability to substance used disorders. To shed light on this issue, the proposed self-administration system will allow researchers to evaluate social interaction behavior, drug self-administration and compulsive drug-taking behaviors. These behavioral assessments are essential for understanding how social experiences modulate brain-behavior relationships involved in substance used disorders.

This finding is expected to inform future prevention strategies and supports the development of more effective therapeutic interventions for substance use disorders. Please see notice attached.

## Publications

- July 7, 2025: Sources sought, due July 17, 2025 at 3:00 PM EDT. Notice 3f6e50ab3df24ce08355e70538b39f43. https://sam.gov/workspace/contract/opp/3f6e50ab3df24ce08355e70538b39f43/view

## Points of contact

- Scott Duernberger, scott.duernberger@nih.gov, 3015940670
- Josh Lazarus, josh.lazarus@nih.gov, 3018276923

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Source: SAM.gov Contract Opportunities bulk extract. Confirm deadlines on SAM.gov before responding. Cite https://abierto.us/opportunities/75n95025q00203.