# Notice of Intent to Sole Source - Chemistry Center for Combating Antibiotic-Resistant Bacteria (CC4CARB)

Canonical: https://abierto.us/opportunities/75n93024r00022

- Solicitation number: 75N93024R00022
- Notice type: Special notice (first published as presolicitation)
- Status: Closed. Deadline was May 8, 2026 at 3:00 PM EDT
- Department: Department of Health and Human Services
- Agency: National Institutes of Health
- Contracting office: National Institutes of Health Niaid (75N930)
- NAICS: 541714 Research and Development in Biotechnology (except Nanobiotechnology)
- Product or service code: AN12 Health R&D Services; Health Care Services; Applied Research
- Place of performance: Rockville, Maryland
- County: Montgomery County (FIPS 24031). https://abierto.us/counties/montgomery-county-md-24031
- City: Rockville. https://abierto.us/cities/rockville-md-2467675
- First posted: October 17, 2024
- Last posted: May 7, 2026
- SAM.gov: https://sam.gov/workspace/contract/opp/5c5234ac16114489a21098a4ce84d04c/view

## Description

The aim of this solicitation is to continue the Chemistry Center for Combating Antibiotic-Resistant Bacteria (CC4CARB) responsible for coordinating and conducting the design, synthesis, in vitro testing, and distribution of chemical libraries of discrete natural products and small-molecules with diverse physicochemical properties, specifically designed to target Gram-negative bacterial pathogens and other antibiotic-resistant bacteria identified as Antimicrobial Resistance threats.

The contract shall consist of requirements in four (4) key areas: 1) Library Design, 2) Compound Synthesis, 3) Compound Testing, and 4) Compound Management, and includes Project Management of all efforts across these requirements. Any responsible offeror may submit a proposal which will be considered by the Agency. This RFP will be available electronically on April 08, 2026, and may be accessed through https://sam.gov/.

Please note: After opening/downloading the solicitation in the Chrome browser, click the down arrow and select "Open with system viewer" to view the RFP in Adobe Acrobat. This process will allow the links in Section J of the RFP to work properly. This notice does not commit the Government to award a contract. No collect calls will be accepted. No facsimile transmissions will be accepted.

For this solicitation, the NIAID requires proposals to be submitted online via the NIAID electronic Contract Proposal Submission (eCPS) website. Submission of proposals by facsimile or e-mail is not acceptable. For directions on using eCPS, go to the website https://ecps.nih.gov/ and then click on "How to Submit."

## Publications

- October 17, 2024: Presolicitation, due November 1, 2024 at 3:00 PM EDT. Notice 605a4cd2137042be88f11a1a5f109e5b. https://sam.gov/workspace/contract/opp/605a4cd2137042be88f11a1a5f109e5b/view
- April 8, 2026: Solicitation, due May 8, 2026 at 3:00 PM EDT. Notice 28d776fea50c4710805eaf478bb029c5. https://sam.gov/workspace/contract/opp/28d776fea50c4710805eaf478bb029c5/view
- April 8, 2026: Solicitation, due May 8, 2026 at 3:00 PM EDT. Notice db49f8f3a5df457a8004c55dc0484540. https://sam.gov/workspace/contract/opp/db49f8f3a5df457a8004c55dc0484540/view
- April 9, 2026: Special notice, due May 8, 2026 at 3:00 PM EDT. Notice f5846a87729242f590136854b320b17d. https://sam.gov/workspace/contract/opp/f5846a87729242f590136854b320b17d/view
- April 27, 2026: Special notice, due May 8, 2026 at 3:00 PM EDT. Notice d9e04492f7964c81a313a4f44dbfb986. https://sam.gov/workspace/contract/opp/d9e04492f7964c81a313a4f44dbfb986/view
- April 27, 2026: Special notice, due May 8, 2026 at 3:00 PM EDT. Notice ea04f81ed319493e88e6797726a65103. https://sam.gov/workspace/contract/opp/ea04f81ed319493e88e6797726a65103/view
- May 7, 2026: Special notice, due May 15, 2026 at 3:00 PM EDT. Notice 5c5234ac16114489a21098a4ce84d04c. https://sam.gov/workspace/contract/opp/5c5234ac16114489a21098a4ce84d04c/view

## Points of contact

- Ignacio Reyes, Contracting Officer, ignacio.reyes@nih.gov, 3014357574
- Jonathan Bryan, jonathan.bryan@nih.gov, 2406695180

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Source: SAM.gov Contract Opportunities bulk extract. Confirm deadlines on SAM.gov before responding. Cite https://abierto.us/opportunities/75n93024r00022.