# Nanobody Affinity Maturation using Phage Display Selection

Canonical: https://abierto.us/opportunities/75n91025q00049

- Solicitation number: 75N91025Q00049
- Notice type: Justification (first published as presolicitation)
- Status: Awarded to Creative Biolabs Inc.
- Department: Department of Health and Human Services
- Agency: National Institutes of Health
- Contracting office: NIH NCI (75N910)
- NAICS: 541714 Research and Development in Biotechnology (except Nanobiotechnology)
- Product or service code: Q301 Reference Laboratory Testing
- Place of performance: Rockville, Maryland
- County: Montgomery County (FIPS 24031). https://abierto.us/counties/montgomery-county-md-24031
- City: Rockville. https://abierto.us/cities/rockville-md-2467675
- First posted: July 18, 2025
- Last posted: September 16, 2025
- SAM.gov: https://sam.gov/workspace/contract/opp/6c18c8f034864d38b989325e7b0e037d/view

## Description

The purpose of this purchase order is to acquire services to perform targeted affinity maturation of an anti-human BCMA nanobody via phage display library construction and selection. The objective is to deliver five affinity-optimized nanobody sequences along with sufficient purified protein for in vitro and in vivo testing.

## Award on USAspending

- Recipient: Creative Biolabs Inc. (UEI V595TMBX2117)
- Contract: 75N91025P00452, purchase order
- Obligated: $112,658.00
- Competition: Not Competed Under SAP, 1 offers received
- Link: award number 75N91025P00452 equals the contract number; same awarding office 75N910 (high confidence)
- Record: https://www.usaspending.gov/award/CONT_AWD_75N91025P00452_7529_-NONE-_-NONE-/


## Publications

- July 18, 2025: Presolicitation, due August 1, 2025 at 3:00 PM EDT. Notice f76f2ca07f184664be480c178daedfa0. https://sam.gov/workspace/contract/opp/f76f2ca07f184664be480c178daedfa0/view
- September 16, 2025: Justification. Notice 6c18c8f034864d38b989325e7b0e037d. https://sam.gov/workspace/contract/opp/6c18c8f034864d38b989325e7b0e037d/view

## Points of contact

- Michelle Nguyen, michelle.nguyen2@nih.gov, 3014017

---
Source: SAM.gov Contract Opportunities bulk extract and USAspending.gov award data. Confirm deadlines on SAM.gov before responding. Cite https://abierto.us/opportunities/75n91025q00049.