# National Cancer Institute (NCI) Small Business Innovation Research (SBIR) Innovative Concept Award Program – Fiscal Year 2025

Canonical: https://abierto.us/opportunities/75n91024r00013

- Solicitation number: 75N91024R00013
- Notice type: Solicitation (first published as presolicitation)
- Status: Awarded to Pathcision Medicine, Inc.
- Department: Department of Health and Human Services
- Agency: National Institutes of Health
- Contracting office: NIH NCI (75N910)
- NAICS: 54171 Research and Development in the Physical, Engineering, and Life Sciences
- Product or service code: AN12 Health R&D Services; Health Care Services; Applied Research
- Set-aside: Total small business set-aside
- County: Middlesex County (FIPS 25017). https://abierto.us/counties/middlesex-county-ma-25017
- First posted: March 28, 2024
- Last posted: April 12, 2024
- SAM.gov: https://sam.gov/workspace/contract/opp/43856fb93e9042b28c10e285d3aacb89/view

## Description

The National Cancer Institute is soliciting proposals from small business concerns to perform key activities to demonstrate technical feasibility and proof-of-concept for the development of highly innovative and potentially transformative technologies in the following areas: Development of therapeutic or preventative technologies for treatment or prevention of Pediatric Cancers and/or Rare Cancers.

Development of devices, diagnostic technologies, or digital health tools for treatment, detection, and diagnosis of Pediatric Cancers and/or Rare Cancers. For this solicitation rare cancers with a 5-year survival rate of less than 50 % are encouraged and rare cancers would be defined as including all the cancers listed by the NIH Genetics and Rare Diseases Information Center. The list can be found here: https://rarediseases.info.nih.gov/search-result?category=Cancer.

Access the NCI Surveillance, Epidemiology, and End Results Program (SEER) database (https://seer.cancer.gov/) for more information regarding 5-year cancer survival rates. Preliminary data is not required; however, the ideas should have sound scientific premise either based on the offeror’s own research or literature evidence. Proposals will need to identify an anticipated product that will be developed and clearly lay out the anticipated development path.

Proposals will need to clearly identify the clinical problem and cancer type(s) that the proposal will focus on with adequate justification. In addition, the offerors should propose experiments to obtain initial de-risking and proof-of-concept data. Awards will also include requirements to enhance entrepreneurship skills and to develop or refine a business model and commercialization plan.

This solicitation is a Concept Award program that could serve as a pipeline for the federal Small Business Innovation Research (SBIR) program. Background for the SBIR program can be found in the Small Business Administration’s policy directive found here: https://www.sbir.gov/sites/default/files/SBA%20SBIR_STTR_POLICY_DIRECTIVE_May2023.pdf

## Award on USAspending

- Recipient: Aso Therapeutics, Inc. (UEI K8R9YHMX6Q31)
- Contract: 75N91025C00011, definitive contract
- Obligated: $299,991.00
- Competition: Full and Open Competition After Exclusion of Sources, 55 offers received
- Link: solicitation number 75N91024R00013 equals the FPDS solicitation identifier; same awarding office 75N910 (high confidence)
- Record: https://www.usaspending.gov/award/CONT_AWD_75N91025C00011_7529_-NONE-_-NONE-/

- Recipient: Tenaci-T Therapeutics LLC (UEI MTRTYVL8N717)
- Contract: 75N91025C00012, definitive contract
- Obligated: $297,621.00
- Competition: Full and Open Competition After Exclusion of Sources, 55 offers received
- Link: solicitation number 75N91024R00013 equals the FPDS solicitation identifier; same awarding office 75N910 (high confidence)
- Record: https://www.usaspending.gov/award/CONT_AWD_75N91025C00012_7529_-NONE-_-NONE-/

- Recipient: Pathcision Medicine, Inc. (UEI CK6QRF2GLBT1)
- Contract: 75N91025C00018, definitive contract
- Obligated: $299,981.00
- Competition: Full and Open Competition After Exclusion of Sources, 55 offers received
- Link: solicitation number 75N91024R00013 equals the FPDS solicitation identifier; same awarding office 75N910 (high confidence)
- Record: https://www.usaspending.gov/award/CONT_AWD_75N91025C00018_7529_-NONE-_-NONE-/

- Recipient: Cloverleaf Bio, Inc. (UEI NR4GYWZ66HM5)
- Contract: 75N91025C00020, definitive contract
- Obligated: $300,000.00
- Competition: Full and Open Competition After Exclusion of Sources, 55 offers received
- Link: solicitation number 75N91024R00013 equals the FPDS solicitation identifier; same awarding office 75N910 (high confidence)
- Record: https://www.usaspending.gov/award/CONT_AWD_75N91025C00020_7529_-NONE-_-NONE-/

- Recipient: Tippingpoint Biosciences, Inc. (UEI SECRMGV8SX87)
- Contract: 75N91025C00021, definitive contract
- Obligated: $300,000.00
- Competition: Full and Open Competition After Exclusion of Sources, 52 offers received
- Link: solicitation number 75N91024R00013 equals the FPDS solicitation identifier; same awarding office 75N910 (high confidence)
- Record: https://www.usaspending.gov/award/CONT_AWD_75N91025C00021_7529_-NONE-_-NONE-/

- Recipient: Merlin Biotech Inc. (UEI U33SZN8R3966)
- Contract: 75N91025C00025, definitive contract
- Obligated: $300,000.00
- Competition: Full and Open Competition After Exclusion of Sources, 55 offers received
- Link: solicitation number 75N91024R00013 equals the FPDS solicitation identifier; same awarding office 75N910 (high confidence)
- Record: https://www.usaspending.gov/award/CONT_AWD_75N91025C00025_7529_-NONE-_-NONE-/

- Recipient: Syzonc, Inc. (UEI JRJ6JNJ2CHF3)
- Contract: 75N91025C00027, definitive contract
- Obligated: $299,878.00
- Competition: Full and Open Competition After Exclusion of Sources, 55 offers received
- Link: solicitation number 75N91024R00013 equals the FPDS solicitation identifier; same awarding office 75N910 (high confidence)
- Record: https://www.usaspending.gov/award/CONT_AWD_75N91025C00027_7529_-NONE-_-NONE-/


## Publications

- March 28, 2024: Presolicitation, due April 12, 2024 at 5:00 PM EDT. Notice 56789d3538e44d668456532c5766c190. https://sam.gov/workspace/contract/opp/56789d3538e44d668456532c5766c190/view
- April 12, 2024: Solicitation, due September 23, 2024 at 5:00 PM EDT. Notice 43856fb93e9042b28c10e285d3aacb89. https://sam.gov/workspace/contract/opp/43856fb93e9042b28c10e285d3aacb89/view

## Points of contact

- Tanya Renwick, ncioasbir@mail.nih.gov

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Source: SAM.gov Contract Opportunities bulk extract and USAspending.gov award data. Confirm deadlines on SAM.gov before responding. Cite https://abierto.us/opportunities/75n91024r00013.