# Center for Biologics Evaluation and Research (CBER) DBPAP/ Amb a 1-Specific Aptamers

Canonical: https://abierto.us/opportunities/75f40124q00548

- Solicitation number: 75F40124Q00548
- Notice type: Solicitation
- Status: Awarded to Aptagen LLC
- Department: Department of Health and Human Services
- Agency: Food and Drug Administration
- Contracting office: FDA Office of Acq Grant SVCS (75F401)
- NAICS: 325414 Biological Product (except Diagnostic) Manufacturing
- Product or service code: B504 Chemical/Biological Studies and Analysis
- Set-aside: Total small business set-aside
- Place of performance: Silver Spring, Maryland
- County: Montgomery County (FIPS 24031). https://abierto.us/counties/montgomery-county-md-24031
- City: Silver Spring. https://abierto.us/cities/silver-spring-md-2472450
- First posted: September 19, 2024
- Last posted: September 25, 2024
- SAM.gov: https://sam.gov/workspace/contract/opp/d56340726c714a0194e1707063a30f69/view

## Description

PER AMENDMENT 1 - Proposal Receipt date/time extended to 9/27/2024 at 12:00 pm EST.

Introduction Development of Amb a 1- Specific capture and biotin-labeled detection Aptamers for use in Enzyme Linked Immunosorbent Assay (ELISA)/ImmunoEnzymetric Assay (IEMA) Background In the United States ragweed allergen extracts are standardized, which means that their potencies are determined in comparison to a US Reference Standard. Potency of the extract is determined by measuring Amb a 1 content.

The Laboratory of Immunobiochemistry (LIB) needs to develop reference standard Amb a 1-specific capture and biotin-labeled detection monoclonal aptamers suitable for use in Enzyme Linked Immunosorbent Assay (ELISA)/ImmunoEnzymetric Assay (IEMA) to measure biological potencies of commercial ragweed pollen extracts marketed in the United States. Scope Amb a 1-specific capture and biotin-labeled detection monoclonal antibodies suitable for use in Enzyme Linked Immunosorbent Assay (ELISA)/ImmunoEnzymetric Assay (IEMA).

## Award on USAspending

- Recipient: Aptagen LLC (UEI HEK9BF17MKL3)
- Contract: 75F40124P00523, purchase order
- Obligated: $100,000.00
- Competition: Competed Under SAP, 3 offers received
- Link: solicitation number 75F40124Q00548 equals the FPDS solicitation identifier; same awarding office 75F401 (high confidence)
- Record: https://www.usaspending.gov/award/CONT_AWD_75F40124P00523_7524_-NONE-_-NONE-/


## Publications

- September 19, 2024: Solicitation, due September 26, 2024 at 2:00 PM EDT. Notice f629c2ee7e9e49769976bf57c26ec2dc. https://sam.gov/workspace/contract/opp/f629c2ee7e9e49769976bf57c26ec2dc/view
- September 25, 2024: Solicitation, due September 27, 2024 at 12:00 PM EDT. Notice 6f6bce7e8f58444b8332c459b3df41bd. https://sam.gov/workspace/contract/opp/6f6bce7e8f58444b8332c459b3df41bd/view
- September 25, 2024: Solicitation, due September 27, 2024 at 12:00 PM EDT. Notice d56340726c714a0194e1707063a30f69. https://sam.gov/workspace/contract/opp/d56340726c714a0194e1707063a30f69/view

## Points of contact

- Nicholas Bisher, Nicholas.Bisher@fda.hhs.gov

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Source: SAM.gov Contract Opportunities bulk extract and USAspending.gov award data. Confirm deadlines on SAM.gov before responding. Cite https://abierto.us/opportunities/75f40124q00548.