{"canonical":"https://abierto.us/opportunities/75f40124q00318","key":"75F40124Q00318","url":"https://abierto.us/opportunities/75f40124q00318","title":"Amendment Two: Lease of an add-on device capable of long-read length sequencing compatible with Oxford NanoPore GridION and purchase of consumables","solicitation_number":"75F40124Q00318","notice_type":"k","open":false,"response_deadline":"2024-08-29T14:00:00Z","first_posted":"2024-07-19","last_posted":"2024-08-25","department":"HEALTH AND HUMAN SERVICES, DEPARTMENT OF","subagency":"FOOD AND DRUG ADMINISTRATION","office":"FDA OFFICE OF ACQ GRANT SVCS","naics":"334516","psc":"6640","set_aside":null,"place_state":"MD","place_county":"24033","place_county_name":"Prince George's County","place_city":"2445900","place_city_name":"Laurel","winner":"OXFORD NANOPORE TECHNOLOGIES INC","award_amount":null,"publications":[{"notice_id":"52cede4f2a2c4fbe8c65961c30f9c298","title":"Lease of an add-on device capable of long-read length sequencing compatible with Oxford NanoPore GridION and purchase of consumables","solicitation_number":"75F40124Q00318","notice_type":"k","base_type":"k","posted":"2024-07-19","posted_at":null,"due_at":"2024-07-31T14:00:00Z","due_date":"2024-07-31","cancelled":null,"archived":null,"archive_date":"2024-08-15","award_number":null,"awardee_name":null,"amount":null,"link_sam":"https://sam.gov/workspace/contract/opp/52cede4f2a2c4fbe8c65961c30f9c298/view","enriched":false,"history":[]},{"notice_id":"1fe96aa810dd405e81d886b5b6518474","title":"Amendment One: Lease of an add-on device capable of long-read length sequencing compatible with Oxford NanoPore GridION and purchase of consumables","solicitation_number":"75F40124Q00318","notice_type":"k","base_type":"k","posted":"2024-07-27","posted_at":null,"due_at":"2024-08-12T14:00:00Z","due_date":"2024-08-12","cancelled":null,"archived":null,"archive_date":"2024-08-27","award_number":null,"awardee_name":null,"amount":null,"link_sam":"https://sam.gov/workspace/contract/opp/1fe96aa810dd405e81d886b5b6518474/view","enriched":false,"history":[]},{"notice_id":"7294bf9c798b4c0882bd1c140625f02f","title":"Amendment Two: Lease of an add-on device capable of long-read length sequencing compatible with Oxford NanoPore GridION and purchase of consumables","solicitation_number":"75F40124Q00318","notice_type":"k","base_type":"k","posted":"2024-08-25","posted_at":null,"due_at":"2024-08-29T14:00:00Z","due_date":"2024-08-29","cancelled":null,"archived":null,"archive_date":"2024-09-13","award_number":null,"awardee_name":null,"amount":null,"link_sam":"https://sam.gov/workspace/contract/opp/7294bf9c798b4c0882bd1c140625f02f/view","enriched":false,"history":[]}],"latest_notice_id":"7294bf9c798b4c0882bd1c140625f02f","first_type":"k","notices":[{"dates":{"posted":"2024-07-19","response_deadline":{"raw":"2024-07-31T10:00:00-04:00","utc":"2024-07-31T14:00:00Z","date":"2024-07-31","time":"10:00:00","utc_offset_seconds":-14400}},"links":{"sam":"https://sam.gov/workspace/contract/opp/52cede4f2a2c4fbe8c65961c30f9c298/view"},"naics":{"codes":["334516"],"primary":"334516"},"title":"Lease of an add-on device capable of long-read length sequencing compatible with Oxford NanoPore GridION and purchase of consumables","agency":{"office":{"code":"75F401","name":"FDA OFFICE OF ACQ GRANT SVCS"},"subtier":{"code":"7524","name":"FOOD AND DRUG ADMINISTRATION"},"department":{"code":"075","name":"HEALTH AND HUMAN SERVICES, DEPARTMENT OF"},"office_address":{"zip":"20852","city":"Rockville","state":"MD","country":"USA"},"organization_type":"OFFICE"},"status":{"active":false,"archive_date":"2024-08-15","archive_type":"auto15"},"contacts":[{"name":"PATRICIA NATIVIDAD","role":"primary","email":"PATRICIA.NATIVIDAD@FDA.HHS.GOV","phone":"3017968919"}],"base_type":{"code":"k","label":"Combined Synopsis/Solicitation"},"notice_id":"52cede4f2a2c4fbe8c65961c30f9c298","provenance":{"extract":{"url":"https://s3.amazonaws.com/falextracts/Contract%20Opportunities/Archived%20Data/FY2024_archived_opportunities.csv","etag":"\"d582488fe153a9f11bf629913d176ffc-137\"","fetched_at":"2026-09-16T19:07:39.720164Z","row_sha256":"8a7ca6a272e9064f902f4b736f9d9de30811af61b908f980c6df44fd68fb2040","last_modified":"2026-09-13T14:47:40Z"},"updated_at":"2026-09-16T19:07:39.720164Z","first_seen_at":"2026-09-16T19:07:39.720164Z"},"description":{"text":"This is a combined synopsis/solicitation for commercial services prepared in accordance with the format in FAR 12.6 as supplemented with FAR 13 and additional information included in this notice. The incorporated provisions and clauses are those in effect through Federal Acquisition Circular (FAC) 2024-05. THIS ANNOUNCEMENT CONSTITUTES THE ONLY SOLICITATION AND A SEPARATE SOLICITATION WILL NOT BE ISSUED. The solicitation number for this acquisition is 75F40124Q00381 and is being issued as a Request for Quote (RFQ). The NAICS Code for this solicitation is 334516 and Full and Open Competition. This will be awarded as Firm-Fixed Price. Prospective Offerors are responsible for downloading the solicitation and any amendments from SAM.gov. The Government reserves the right to award an order without discussions if the Contracting Officer determines that the initial offer is providing the Best Value and discussions are not necessary. The Government intends to issue a Purchase Order. The U.S. Food and Drug Administration (FDA) has a need to Lease Oxford Nanopore PromethION 2 Solo long read sequencing instrument and purchase of consumables. ******************BRAND NAME OR EQUAL***************************** BACKGROUND AND OVERVIEW Traditional next generation sequencing of whole genomes is done in short 75bp – 150bp fragments. However, these short reads are not optimal for discovering large scale genomic changes, as they will not align to the reference genome using established pipelines. To ascertain whether large scale genomic rearrangements have occurred, an instrument with long read length sequencing technology is required. The Division of Applied Veterinary Research at the Center for Veterinary Medicine’s Office of Applied Science (CVM/OAS/DAVR) requires an instrument with long read length capability that can sequence a mammalian genome in a cost-effective manner to perform our studies on the safety of gene editing technologies in food and drug producing animals. In addition, the Division of Emerging Technologies at the Center for Veterinary Medicine’s Office of Applied Science (CVM/OAS/DET) needs specific Oxford Nanopore consumables in support of multiple studies. SCOPE This acquisition is for the lease of an Oxford Nanopore PromethION 2 Solo long read sequencing instrument and purchase of consumables. This SOW covers a device and consumables, which must be cross compatible with each other, and the device shall be compatible with an existing instrument in our laboratory, the Oxford Nanopore GridION. If the device is normally offered to other lessees in conjunction with consumables, the consumables should also be offered in the contract. See the Attachment for the Combined Synopsis Solicitation in full text.","origin":"extract"},"notice_type":{"code":"k","label":"Combined Synopsis/Solicitation"},"schema_version":1,"solicitation_number":"75F40124Q00318","place_of_performance":{"zip":"20708","city":{"name":"Laurel"},"state":{"code":"MD"},"country":{"code":"USA"}},"product_service_code":"6640"},{"dates":{"posted":"2024-07-27","response_deadline":{"raw":"2024-08-12T10:00:00-04:00","utc":"2024-08-12T14:00:00Z","date":"2024-08-12","time":"10:00:00","utc_offset_seconds":-14400}},"links":{"sam":"https://sam.gov/workspace/contract/opp/1fe96aa810dd405e81d886b5b6518474/view"},"naics":{"codes":["334516"],"primary":"334516"},"title":"Amendment One: Lease of an add-on device capable of long-read length sequencing compatible with Oxford NanoPore GridION and purchase of consumables","agency":{"office":{"code":"75F401","name":"FDA OFFICE OF ACQ GRANT SVCS"},"subtier":{"code":"7524","name":"FOOD AND DRUG ADMINISTRATION"},"department":{"code":"075","name":"HEALTH AND HUMAN SERVICES, DEPARTMENT OF"},"office_address":{"zip":"20852","city":"Rockville","state":"MD","country":"USA"},"organization_type":"OFFICE"},"status":{"active":false,"archive_date":"2024-08-27","archive_type":"auto15"},"contacts":[{"name":"PATRICIA NATIVIDAD","role":"primary","email":"PATRICIA.NATIVIDAD@FDA.HHS.GOV","phone":"3017968919"}],"base_type":{"code":"k","label":"Combined Synopsis/Solicitation"},"notice_id":"1fe96aa810dd405e81d886b5b6518474","provenance":{"extract":{"url":"https://s3.amazonaws.com/falextracts/Contract%20Opportunities/Archived%20Data/FY2024_archived_opportunities.csv","etag":"\"d582488fe153a9f11bf629913d176ffc-137\"","fetched_at":"2026-09-16T19:07:39.720164Z","row_sha256":"0463dbad5f75680644ca1017558514758dc49cdeb0b139f79cfc6e36e686e4fb","last_modified":"2026-09-13T14:47:40Z"},"updated_at":"2026-09-16T19:07:39.720164Z","first_seen_at":"2026-09-16T19:07:39.720164Z"},"description":{"text":"Amendment One 75F40124Q00318_00001 1. The resaon for the following amendment is to extend the Combined Synopsis Solicitation till August 12, 2024 at 10 am Eastern Time. 2. All other terms and conditions remain the same. ************************************************************************************************************************************************ This is a combined synopsis/solicitation for commercial services prepared in accordance with the format in FAR 12.6 as supplemented with FAR 13 and additional information included in this notice. The incorporated provisions and clauses are those in effect through Federal Acquisition Circular (FAC) 2024-05. THIS ANNOUNCEMENT CONSTITUTES THE ONLY SOLICITATION AND A SEPARATE SOLICITATION WILL NOT BE ISSUED. The solicitation number for this acquisition is 75F40124Q00381 and is being issued as a Request for Quote (RFQ). The NAICS Code for this solicitation is 334516 and Full and Open Competition. This will be awarded as Firm-Fixed Price. Prospective Offerors are responsible for downloading the solicitation and any amendments from SAM.gov. The Government reserves the right to award an order without discussions if the Contracting Officer determines that the initial offer is providing the Best Value and discussions are not necessary. The Government intends to issue a Purchase Order. The U.S. Food and Drug Administration (FDA) has a need to Lease Oxford Nanopore PromethION 2 Solo long read sequencing instrument and purchase of consumables. ******************BRAND NAME OR EQUAL***************************** BACKGROUND AND OVERVIEW Traditional next generation sequencing of whole genomes is done in short 75bp – 150bp fragments. However, these short reads are not optimal for discovering large scale genomic changes, as they will not align to the reference genome using established pipelines. To ascertain whether large scale genomic rearrangements have occurred, an instrument with long read length sequencing technology is required. The Division of Applied Veterinary Research at the Center for Veterinary Medicine’s Office of Applied Science (CVM/OAS/DAVR) requires an instrument with long read length capability that can sequence a mammalian genome in a cost-effective manner to perform our studies on the safety of gene editing technologies in food and drug producing animals. In addition, the Division of Emerging Technologies at the Center for Veterinary Medicine’s Office of Applied Science (CVM/OAS/DET) needs specific Oxford Nanopore consumables in support of multiple studies. SCOPE This acquisition is for the lease of an Oxford Nanopore PromethION 2 Solo long read sequencing instrument and purchase of consumables. This SOW covers a device and consumables, which must be cross compatible with each other, and the device shall be compatible with an existing instrument in our laboratory, the Oxford Nanopore GridION. If the device is normally offered to other lessees in conjunction with consumables, the consumables should also be offered in the contract. See the Attachment for the Combined Synopsis Solicitation in full text.","origin":"extract"},"notice_type":{"code":"k","label":"Combined Synopsis/Solicitation"},"schema_version":1,"solicitation_number":"75F40124Q00318","place_of_performance":{"zip":"20708","city":{"name":"Laurel"},"state":{"code":"MD"},"country":{"code":"USA"}},"product_service_code":"6640"},{"dates":{"posted":"2024-08-25","response_deadline":{"raw":"2024-08-29T10:00:00-04:00","utc":"2024-08-29T14:00:00Z","date":"2024-08-29","time":"10:00:00","utc_offset_seconds":-14400}},"links":{"sam":"https://sam.gov/workspace/contract/opp/7294bf9c798b4c0882bd1c140625f02f/view"},"naics":{"codes":["334516"],"primary":"334516"},"title":"Amendment Two: Lease of an add-on device capable of long-read length sequencing compatible with Oxford NanoPore GridION and purchase of consumables","agency":{"office":{"code":"75F401","name":"FDA OFFICE OF ACQ GRANT SVCS"},"subtier":{"code":"7524","name":"FOOD AND DRUG ADMINISTRATION"},"department":{"code":"075","name":"HEALTH AND HUMAN SERVICES, DEPARTMENT OF"},"office_address":{"zip":"20852","city":"Rockville","state":"MD","country":"USA"},"organization_type":"OFFICE"},"status":{"active":false,"archive_date":"2024-09-13","archive_type":"auto15"},"contacts":[{"name":"PATRICIA NATIVIDAD","role":"primary","email":"PATRICIA.NATIVIDAD@FDA.HHS.GOV","phone":"3017968919"}],"base_type":{"code":"k","label":"Combined Synopsis/Solicitation"},"notice_id":"7294bf9c798b4c0882bd1c140625f02f","provenance":{"extract":{"url":"https://s3.amazonaws.com/falextracts/Contract%20Opportunities/Archived%20Data/FY2024_archived_opportunities.csv","etag":"\"d582488fe153a9f11bf629913d176ffc-137\"","fetched_at":"2026-09-16T19:07:39.720164Z","row_sha256":"e8fcf0a9b2ba42ab1ce7613d4ef88f12ce056b8b1575d82614d52ae04d869ee7","last_modified":"2026-09-13T14:47:40Z"},"updated_at":"2026-09-16T19:07:39.720164Z","first_seen_at":"2026-09-16T19:07:39.720164Z"},"description":{"text":"The following amendment 2 is for the following reasons: Extent the response date till 8/29/2024 at 10:00 am ET, to add option periods to the Request for Quote. All other terms and conditions remain unchanged. *************************************************************************************** This is a combined synopsis/solicitation for commercial services prepared in accordance with the format in FAR 12.6 as supplemented with FAR 13 and additional information included in this notice. The incorporated provisions and clauses are those in effect through Federal Acquisition Circular (FAC) 2024-05. THIS ANNOUNCEMENT CONSTITUTES THE ONLY SOLICITATION AND A SEPARATE SOLICITATION WILL NOT BE ISSUED. The solicitation number for this acquisition is 75F40124Q00381 and is being issued as a Request for Quote (RFQ). The NAICS Code for this solicitation is 334516 and Full and Open Competition. This will be awarded as Firm-Fixed Price. Prospective Offerors are responsible for downloading the solicitation and any amendments from SAM.gov. The Government reserves the right to award an order without discussions if the Contracting Officer determines that the initial offer is providing the Best Value and discussions are not necessary. The Government intends to issue a Purchase Order. The U.S. Food and Drug Administration (FDA) has a need to Lease Oxford Nanopore PromethION 2 Solo long read sequencing instrument and purchase of consumables. See the Attachment for the AMENDMENT 2 RFQ 75F40124Q00318 in full text.","origin":"extract"},"notice_type":{"code":"k","label":"Combined Synopsis/Solicitation"},"schema_version":1,"solicitation_number":"75F40124Q00318","place_of_performance":{"zip":"20708","city":{"name":"Laurel"},"state":{"code":"MD"},"country":{"code":"USA"}},"product_service_code":"6640"}],"due_at":"2024-08-29T14:00:00Z","due_date":"2024-08-29","closes_at":"2024-08-29T14:00:00Z","awardable":false,"dept_key":"d-075","dept_name":"HEALTH AND HUMAN SERVICES, DEPARTMENT OF","sub_key":"s-7524","sub_name":"FOOD AND DRUG ADMINISTRATION","office_key":"o-75F401","office_name":"FDA OFFICE OF ACQ GRANT SVCS","state":"MD","county":"24033","county_name":"Prince George's County","city":"2445900","city_name":"Laurel","country":"USA","winner_key":"FM6MMNBM2TQ5","amount":null,"linked_awards":3,"cancelled":false,"archived":false,"updated_at":"2026-09-16T21:18:12.857524Z","principal_notice_id":"7294bf9c798b4c0882bd1c140625f02f","description":{"text":"The following amendment 2 is for the following reasons: Extent the response date till 8/29/2024 at 10:00 am ET, to add option periods to the Request for Quote. 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The Government reserves the right to award an order without discussions if the Contracting Officer determines that the initial offer is providing the Best Value and discussions are not necessary. The Government intends to issue a Purchase Order. The U.S. Food and Drug Administration (FDA) has a need to Lease Oxford Nanopore PromethION 2 Solo long read sequencing instrument and purchase of consumables. 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