# Oligo CVV Production

Canonical: https://abierto.us/opportunities/75d30124q78627

- Solicitation number: 75D301-24-Q-78627
- Notice type: Solicitation
- Status: Closed. Deadline was September 16, 2024 at 3:00 PM EDT
- Department: Department of Health and Human Services
- Agency: Centers for Disease Control and Prevention
- Contracting office: CDC Office of Acquisition Services (75D301)
- NAICS: 325414 Biological Product (except Diagnostic) Manufacturing
- Product or service code: Q301 Reference Laboratory Testing
- Place of performance: Atlanta, Georgia
- City: Atlanta. https://abierto.us/cities/atlanta-ga-1304000
- First posted: August 15, 2024
- Last posted: September 11, 2024
- SAM.gov: https://sam.gov/workspace/contract/opp/1006693988424888b4174c8751a29920/view

## Description

**UPDATE (09/11/2024):** The Request for Quotes has been reopened and amended to clarify the quantity to be delivered. Quotes are now due 9/16/2024. See attached amended RFQ for details. See Attached RFQ for Details and Terms The Contractor shall provide the following:

Single-stranded DNA oligonucleotides: Length is understood to be a significant difference in the construction, processing, and pricing of oligos: For single-stranded DNA oligonucleotides of up to 60 nucleotides (nt) in length: The turnaround time (TAT) will be one (1) business day with an ordering cutoff of 10:00 a.m. EST (to be shipped same-day overnight for next-day delivery).

The expected minimum yield will be 25 nMole resuspended at 100 ?M in nuclease-free water in a 96-well plate format, with ordering volumes of up to 8 plates per day. For single-stranded DNA oligonucleotides of up to 80 nucleotides (nt) in length: The turnaround time (TAT) will be one (1) business day with an ordering cutoff of 9:00 a.m. EST (to be shipped same-day overnight for next-day delivery). The expected minimum yield will be 25 nMole resuspended in tubes at 100 ?M in nuclease-free water.

DNA/gene fragments: As with oligos, length is considered a significant factor in the manufacturing of gene fragments, and thus this task can be understood as having different expectations based on length. Double-stranded DNA gene fragments of 300-1,500bp (base pairs) in length with an error rate of less than 1 bp in 5,000bp. The turnaround time (TAT) will be three (3) business days with an ordering cutoff of 11:00 a.m. EST (with the ordering date being day 0).

The expected minimum yield will be 200ng delivered resuspended at 10 ng/µl in a minimum of 20 µl of nuclease-free water. Double-stranded DNA gene fragments of 1,501-2,000bp (base pairs) in length with an error rate of less than 1 bp in 5,000bp. The turnaround time (TAT) will be eight (8) business days with an expected minimum yield of 1,000ng delivered lyophilized in tubes (with the ordering date being day 0).

Double-stranded DNA gene fragments of 2,001-2,250bp (base pairs) in length with an error rate of less than 1 bp in 5,000bp. The turnaround time (TAT) will be eight (8) business days with an expected minimum yield of 1,000ng delivered lyophilized in tubes (with the ordering date being day 0).

## Publications

- August 15, 2024: Solicitation, due August 27, 2024 at 3:00 PM EDT. Notice 356e8ea489264dc89d205ee060ef19e6. https://sam.gov/workspace/contract/opp/356e8ea489264dc89d205ee060ef19e6/view
- September 10, 2024: Solicitation, due August 27, 2024 at 3:00 PM EDT. Notice 767b9922017c47309075dac0e638da68. https://sam.gov/workspace/contract/opp/767b9922017c47309075dac0e638da68/view
- September 11, 2024: Solicitation, due September 16, 2024 at 3:00 PM EDT. Notice 1006693988424888b4174c8751a29920. https://sam.gov/workspace/contract/opp/1006693988424888b4174c8751a29920/view

## Points of contact

- Timothy Joyce, xvf7@cdc.gov

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Source: SAM.gov Contract Opportunities bulk extract. Confirm deadlines on SAM.gov before responding. Cite https://abierto.us/opportunities/75d30124q78627.